This ForgottenIbogaine Psychedelic Could Revolutionize Traumatic Brain Injury Treatment


Ibogaine is currently among the buzziest psychedelics, promising to upend the landscape of mental health care and support. First discovered to curb addiction in the 1960s, the drug was declared an illegal substance by the 1970s. Now, ibogaine is making a comeback not only for treating addiction but anxiety, depression, and now traumatic brain injuries.

In a study published Friday in the journal Nature Medicine, military veterans with mostly mild traumatic brain injuries underwent a combination treatment of magnesium and ibogaine in Mexico, where the psychedelic is legal. One month following their treatment, the individuals reported feeling immense relief from symptoms associated with post-traumatic stress disorder (PTSD), anxiety, and depression, as well as improved cognition.

“No other drug has ever been able to alleviate the functional and neuropsychiatric symptoms of traumatic brain injury,” Nolan Williams, an associate professor of psychiatry and behavioral sciences at Stanford University School of Medicine, who led the study, said in a press release. “The results are dramatic, and we intend to study this compound further.”

“Living in a blizzard”

Ibogaine is a naturally occurring compound found in the roots of a shrub called Tabernanthe iboga, which is native to Central Africa and has been used for centuries for ceremonial practices.

Ibogaine acts as a stimulant in small doses but is a powerful psychedelic in large doses. What it does in the brain, however, isn’t well understood. Studies in rats show that ibogaine may increase proteins that encourage neuroplasticity, which could explain how it helps the brain rewire itself, overcoming seemingly hard-set neural patterns of addiction.

While ibogaine isn’t legal in the U.S., that hasn’t deterred a growing number of individuals from flocking to clinics in Mexico (where the substance is unregulated) seeking treatment for addiction and other mental health issues.

“There were a handful of veterans who had gone to this clinic in Mexico and were reporting anecdotally that they had great improvements in all kinds of areas of their lives after taking ibogaine,” Williams said. “Our goal was to characterize those improvements with structured clinical and neurobiological assessments.”

To do this, Williams and his colleagues at Stanford recruited 30 military veterans who had been in special operations with a history of traumatic brain injuries — a condition causing other mental health issues like PTSD, depression, and anxiety — and repeated blast or combat exposures. The participants first underwent neuro- and psychological evaluations at Stanford and, a few days later, traveled by themselves to the Ambio Treatment Clinic located in Tijuana, Mexico.

At the clinic, the group took an oral dose of ibogaine paired with an intravenous drip of magnesium to prevent any side effects to the heart and cardiovascular system, which the psychedelic is known to do. Participants also participated in some wellness activities while at the clinic, such as reiki, meditation, yoga, and massage. They were then re-evaluated at Stanford four to five days and one month after the ibogaine treatment.

The results were significant. The average disability score for the participants before the treatment was equivalent to mild to moderate disability. This changed to no disability on the one-month follow-up. The veterans also reported, on average, an 88 percent reduction in symptoms associated with PTSD, 87 percent for depression, and 81 percent in anxiety relative to before the ibogaine treatment. They also did much better on their cognitive tests with respect to overall concentration, information processing, memory, and impulse control.

“Before the treatment, I was living life in a blizzard with zero visibility and a cold, hopeless, listless feeling,” Sean, a 51-year-old veteran from Arizona with six combat deployments who participated in the study, said in the press release. “After ibogaine, the storm lifted.”

A new frontier

These findings complement other studies involving military veterans that, similarly, have found ibogaine vastly improved cognitive impairment, PTSD, anxiety, and depression.

In light of the promising research thus far, pharmaceutical companies are already gearing up to develop drugs from ibogaine. German-based atai Life Sciences made an ibogaine formulation to treat opioid-use disorder that completed an early phase clinical trial in the U.K. At the University of California, San Francisco, researchers developed an antidepressant that mimics ibogaine’s impact on the protein that transports the neurotransmitter serotonin.

Since this study was purely observational, Williams and his colleagues are interested in expanding their research to include brain imaging to see exactly what sort of structural changes or otherwise are going on. The researchers believe ibogaine could be a veritable game-changer not just for traumatic brain injuries but a whole laundry list of neurological and psychiatric conditions.

“In addition to treating [traumatic brain injury], I think this may emerge as a broader neuro-rehab drug,” Williams said. “I think it targets a whole host of different brain areas and can help us better understand how to treat other forms of PTSD, anxiety, and depression that aren’t necessarily linked to TBI.”

Psychoactive Ibogaine and Magnesium Show Promise for PTSD


Summary: Ibogaine, a plant-based psychoactive drug combined with magnesium, effectively reduces PTSD, anxiety, and depression in veterans with traumatic brain injuries (TBI). The study, involving 30 U.S. special forces veterans, showed significant and lasting improvements in mental health and functioning post-treatment.

Ibogaine’s potential extends beyond TBI, offering hope for broader applications in neuropsychiatric conditions like PTSD and depression. The drug’s safety profile and positive results suggest a promising avenue for veterans’ mental health treatment.

Key Fact:

  1. Ibogaine, in combination with magnesium, leads to significant and lasting improvements in veterans’ mental health and functioning.
  2. This research offers hope for treating traumatic brain injuries (TBI) and broader neuropsychiatric conditions such as PTSD and depression.
  3. Ibogaine’s safety profile and effectiveness suggest potential benefits for veterans’ mental health treatment.

Source: Stanford

For military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head trauma or blast explosions are a leading cause of post-traumatic stress disorder, anxiety, depression and suicide among veterans. Few treatments have been effective at diminishing the long-term effects of TBI, leaving many veterans feeling hopeless. 

Now, Stanford researchers have discovered that the plant-based psychoactive drug ibogaine, when combined with magnesium to protect the heart, safely and effectively reduces PTSD, anxiety and depression and improves functioning in veterans with TBI.

Their new study, to be published online Jan. 5 in Nature Medicine, includes detailed data on 30 veterans of U.S. special forces.

“No other drug has ever been able to alleviate the functional and neuropsychiatric symptoms of traumatic brain injury,” said Nolan Williams, MD, an associate professor of psychiatry and behavioral sciences. “The results are dramatic, and we intend to study this compound further.”

Alternative options

Traumatic brain injury is defined as a disruption in the normal functioning of the brain resulting from external forces — such as explosions, vehicle collisions or other bodily impacts. The trauma associated with TBI can lead to changes in the function and/or structure of the brain, which, in turn, contributes to neuropsychiatric symptoms.

Hundreds of thousands of troops serving in Afghanistan and Iraq have sustained TBIs in recent decades, and these injuries are suspected of playing a role in the high rates of depression and suicide seen among military veterans. With mainstream treatment options not fully effective for some veterans, researchers have sought therapeutic alternatives.

Ibogaine is a naturally occurring compound found in the roots of the African shrub iboga, and it has been used for centuries in spiritual and healing ceremonies.

More recently, it has gained interest from the medical and scientific communities for its potential to treat opioid and cocaine addiction, and research has suggested that it increases signaling of several important molecules within the brain, some of which have been linked to drug addiction and depression.

Since 1970 ibogaine has been designated as a Schedule I drug, preventing its use within the U.S., but clinics in both Canada and Mexico offer legal ibogaine treatments.

“There were a handful of veterans who had gone to this clinic in Mexico and were reporting anecdotally that they had great improvements in all kinds of areas of their lives after taking ibogaine,” Williams said. “Our goal was to characterize those improvements with structured clinical and neurobiological assessments.”

Capturing ‘before and after’

Williams and his colleagues at Stanford teamed up with VETS, Inc., a foundation that helps facilitate psychedelic-assisted therapies for veterans. With support from VETS, 30 special operations veterans with a history of TBI and repeated blast exposures, almost all of whom were experiencing clinically severe psychiatric symptoms and functional disabilities, had independently scheduled themselves for treatment with magnesium and ibogaine at a clinic in Mexico.

Before the treatment, Stanford researchers gauged the participants’ levels of PTSD, anxiety, depression and functioning based on a combination of self-reported questionnaires and clinician-administered assessments.

Participants then traveled to a clinic in Mexico run by Ambio Life Sciences, where under medical monitoring they received oral ibogaine along with magnesium to help prevent heart complications that have been associated with ibogaine. The veterans then returned to Stanford for post-treatment assessments.

“These men were incredibly intelligent, high-performing individuals who experienced life-altering functional disability from TBI during their time in combat,” Williams said. “They were all willing to try most anything that they thought might help them get their lives back.”

At the beginning of the study, participants were experiencing clinically significant levels of disability as measured by the World Health Organization Disability Assessment Scale 2.0, which assesses disability in six functional domains, including cognition, mobility, self-care, getting along, life activities and community participation. In addition, 23 met the criteria for PTSD, 14 for an anxiety disorder and 15 for alcohol use disorder. In their lifetimes, 19 participants had been suicidal and seven had attempted suicide.

Life-changing results

On average, treatment with ibogaine immediately led to significant improvements in functioning, PTSD, depression and anxiety. Moreover, those effects persisted until at least one month after treatment — the endpoint of the study.

Before treatment, the veterans had an average disability rating of 30.2 on the disability assessment scale, equivalent to mild to moderate disability. One month after treatment, that rating improved to 5.1, indicating no disability.

Similarly, one month after treatment participants experienced average reductions of 88% in PTSD symptoms, 87% in depression symptoms and 81% in anxiety symptoms relative to how they were before ibogaine treatment. Formal cognitive testing also revealed improvements in participants’ concentration, information processing, memory and impulsivity.

“I wasn’t willing to admit I was dealing with any TBI challenges. I just thought I’d had my bell rung a few times — until the day I forgot my wife’s name,” said Craig, a 52-year-old study participant from Colorado who served 27 years in the U.S. Navy.

“Since [ibogaine treatment], my cognitive function has been fully restored. This has resulted in advancement at work and vastly improved my ability to talk to my children and wife.”

“Before the treatment, I was living life in a blizzard with zero visibility and a cold, hopeless, listless feeling,” said Sean, a 51-year-old veteran from Arizona with six combat deployments who participated in the study and says ibogaine saved his life. “After ibogaine, the storm lifted.”

Importantly, there were no serious side effects of ibogaine and no instances of the heart problems that have occasionally been linked to ibogaine. During treatment, veterans reported only typical symptoms such as headaches and nausea.

Lessons for PTSD, depression and anxiety

Williams and his team are planning further analysis of additional data collected on the veterans but not included in the current study, including brain scans that could help reveal how ibogaine led to improvements in cognition. They also hope to launch future studies to further understand how the drug might be used to treat TBI.

However, they think ibogaine’s drastic effects on TBI also suggest that it holds broader therapeutic potential for other neuropsychiatric conditions.

“In addition to treating TBI, I think this may emerge as a broader neuro-rehab drug,” Williams said. “I think it targets a whole host of different brain areas and can help us better understand how to treat other forms of PTSD, anxiety and depression that aren’t necessarily linked to TBI.”

The Dose Will See You Now: The Astonishing Life-Saving Potential of Psychedelic Therapy in Modern Medicine


What is your impression after reading the results of this recent study on the potential of a promising new treatment for depression?

‘The main takeaway is that the effects are well-tolerated in this population, and not just that—the antidepressant potential of the treatment seems to be pretty considerable,’ […] ‘All 12 of the patients reported a reduction in the severity of their depression for one week after the psilocybin experience, and for most this was true after three months. At week one, eight patients met standard criteria for remission, with five remaining in remission at three months.’

Encouraging results, no? On the surface, it seems like more people could benefit from a treatment like this.

Unfortunately, at this point in time, they can’t. They’d be considered criminals, for the chosen treatment in this study is currently illegal. In fact, it’s a Schedule 1 substance as classified by the DEA, with “no accepted medical value,” “a lack of accepted safety for use under medical supervision,” and “a high potential for abuse”.

The study was conducted using psilocybin, the active ingredient in magic mushrooms, when given to patients suffering from treatment-resistant depression.

Despite seeing encouraging results such as the above study more frequently, psychedelic therapy remains a taboo topic in both general society and the medical community at large, partially due to the many myths still surrounding the psychedelic experience.

Why is this the case? Let’s dig deeper.

What Is Psychedelic Therapy?

Psychedelic-assisted psychotherapy offers us an unparalleled medical opportunity. Currently, it is typically reserved for ‘treatment-resistant’ illnesses (when standard methods of therapy or medical treatment have previously proven unsuccessful).

The term ‘psychedelic’ comes from a Greek term, essentially translating to ‘mind-revealing’. For anyone suffering from unfamiliar mental illness or trauma, the definition is seemingly self-explanatory.

However, for the uninitiated, it’s helpful to refer to N. Crowley’s definition of ‘psychedelics’ as noted in The British Journal of Psychiatry (“A role for psychedelics in psychiatry?”):

The difference between psychedelics (entheogens) and other psychotropic drugs is that entheogens work as ‘non-specific amplifiers of the psyche,’ inducing an altered or non-ordinary state of consciousness (Grof, 2000). The content and nature of the experiences are not thought to be artificial products of their pharmacological interaction with the brain (‘toxic psychoses’) but authentic expressions of the psyche revealing its functioning on levels not ordinarily available for observation and study.

Psychedelic therapy combines traditional psychotherapy sessions with a trained practitioner, and injects selected sessions with a measured, monitored dose of a psychoactive substance. A placebo is used for some sessions if necessary, and not all sessions are paired with a psychedelic experience.

As with all entheogenic experiences, preparation and post-experience integration are just as, if not more important, than the experience itself.

A typical treatment may look like:

  1. 2-3 regular therapeutic sessions with the doctor.
  2. Preparation (discussion or low-dose introduction) for the experience.
  3. 1 session with a measured dose, under medical supervision/guidance with therapeutic discussion using points derived from preparation stage.
  4. Post-experience discussion and integration.
  5. The cycle of psychedelic session > integration session, can continue as necessary based on the therapist’s recommendation. This is also called psycholytic therapy.
  6. Post-treatment follow-up and monitoring of habits/insights integrated into daily life afterward.

The value of psychedelic therapy is that it can induce in patients a state of being where they can make genuine progress with their struggles. That might mean being able to discuss deep-rooted trauma without judgment or fear, feeling self-compassion for the first time, or removing the general anxieties associated with mental illness.

Remember that at this point in time, these treatments are being used only on patients who have already resisted all other forms of treatments, such as medication, therapy, or some combination thereof.

Psychedelic therapy is proving itself to provide effective treatment for patients who have already been deemed untreatable.

Many patients of these experiences have rated them “the most important [of their lives], or if not, in the top 5 most important experiences of their lives.”

The Unorthodox State of Psychedelic Therapy In Modern Medicine

The state of psychedelic therapy in modern medicine can best be summarized in one word: Taboo.

Taboo as defined as ‘a social or religious custom prohibiting or forbidding discussion of a particular practice or forbidding association with a particular person, place, or thing.’

In many countries around the world, particularly North America, entheogens are classified as a ‘Schedule 1’ substance. This means that they are considered “highly dangerous to user/society” and have “no applicable medical value”.

As we’ll continue to see, nothing could be further from the truth. In fact, studies have shown that psychedelics are not linked to the development of mental health issues or suicidal behavior.

As a result, it’s deceptively difficult to begin studies into any potentially applicable values. Scientists, doctors, and therapists, excitedly exploring these treatments, can be ostracized, shunned, disbanded, or fired.

Without valid study opportunities, psychedelic therapy cannot move away from its current taboo state into a more socially and medically viable option to increase a patient’s overall quality of life.

As a result, previous work has happened in the shadows—in therapists’ homes for private, under-the-table sessions.

This coercion to the outer edges paints psychedelic therapy as a dark art, akin to voodoo from witch doctors, instead of the valid and tangible treatment it should be recognized as.

Recently, however, psychedelic therapy has begun to move out of the shadows and into the spotlight. Recognition from notable figures and interest from major institutions like John Hopkins Universityhave started to emerge. One organization at the forefront of these efforts is MAPS (The Multidisciplinary Association of Psychedelic Studies), which is spearheading fundraising and medically-valid studies into the value and treatment of entheogens as a whole. The New York Times, Vice, The Guardian, and many others have begun to openly analyze the practice, and a more general discussion is emerging.

Early-stage results have come to fruition from initial studies, with outstanding results. Treatments are being shown as successful, and patients are retaining the benefits long-term.

Patients are getting their lives back.

No accepted medical value?

The successful treatment of ‘treatment-resistant’ patients should be considered outstanding medical value.

Of course, the psychedelic community at large has been saying this for years. Impressive anecdotal reports can be found by the hundreds from psychonauts online and in-person. Users who have effectively combatted depression, OCD, and persistent negative thought patterns.

So what exactly are these entheogens patients are using? How are they administered, and what do they address? The following are some of the substances being studied or advocated for in the psychedelic community currently.

Psychedelic Therapy

The Psychedelic Family and Their Therapeutic Applications

There are a plethora of entheogens with promising practical applications. The entheogens in point include psilocybin, ibogaine, LSD, and ayahuasca.

There are other, less prominent, psychedelics also being looked into on a smaller scale. These include DMT, mescaline, and 2C-B.

As each substance is unique in its biochemical composition, it fits that they each have their own neuropsychological effects. We can take a closer look at the proposed or proven benefits of each psychedelic in its therapeutic context.

Psilocybin

Psilocybin is the active ingredient in magic mushrooms. It is quickly claiming its stake as one of the most important substances to pair with traditional therapeutic techniques, due to its proven success at tackling treatment-resistant cases.

 Promising scientific and anecdotal evidence is emerging promoting the ability of psilocybin to alleviate or lessen the symptoms of depression, general anxiety, end-of-life anxiety, and trauma.

Coincidentally, psilocybin can also be effective in the context of couples therapy. It may be possible to save a marriage, or provide a deeper connection to your loved one if this was re-scheduled and introduced to society properly.

Who knew, magic mushrooms might just save your marriage!

Psilocybin is the focus of many emerging studies, and the results are beyond promising (see image below). The quote shared at the beginning of this article was in reference to terminal patients who had undergone their first treatment sessions with psilocybin.

Many ranked it as their most important life experience to date, with some putting on the same level or above the birth of their own child.

Psilocybin-assisted psychotherapy has helped to reduce symptoms and onset of chronic depression, with the effects for most patients lasting between 6-12 months after the experience. This can be extended with effective post-experience integration techniques and follow-up sessions.

Ibogaine

Ibogaine hasn’t had it’s big break yet. It remains on the outer edges to this day, even in the psychedelic community. However, ibogaine is shaping up to be one of the most promising treatments available for patients suffering from opiate addiction or withdrawals.

A single treatment of ibogaine can eradicate the addiction completely, with little to no withdrawal symptoms.

This is something no medical treatment or pharmacological approach has been able to replicate to date.

Ibogaine outperforms any approach to intense addiction currently known to modern science.

And yet it remains a Schedule 1 drug.

Let that sink in.

Despite its unparalleled efficacy, the persistent unpopularity of ibogaine may be due to the fact that the experience is intense. A visceral, multi-day exploration that surfaces key decisions and moments of an addict’s life can be profoundly jarring; it is not something to be taken lightly.

This isn’t your average club drug or even a casual full-day trip in the forest with your friends.

Specifics of the trip aside, the profound efficacy of ibogaine should not be passed up, and fortunately, there are a few organizations (here and here) around the world working to surface these incredible results. Ibogaine is not illegal around the world and is, in fact, a right of passage for some youth in select African countries.

With effective post-experience integration and therapy, addicts who just a few weeks ago had succumbed to the sensual allure of serious drugs are now able to move forward successfully and reclaim the life they may have lost.

Ibogaine can help a user take their lives back from the deathly, devilish clutches of addiction.

LSD

LSD (lysergic acid diethylamide), more commonly referred to as acid, has been in the spotlight for some time. Known to most people as a substance that brings beautiful visual benefits and a deep sense of interconnectedness, when applied in a therapeutic setting, LSD can overhaul cemented opinion structures, altering the individual’s outlook on life and the potential they have in the future.

Due to the incredible introspection, openness, and lucidity LSD provides, there are a plethora of illnesses or vindications that LSD-assisted psychotherapy can effectively combat.

Among these illnesses are: alcoholism, quitting smoking, depression, and general/end-of-life anxiety.

As with the aforementioned substances, LSD is proving both in scientific studies and anecdotal reports to offer profound, life-altering benefits to the user.

Follow the white rabbit, reclaim your life.

A pretty good trade-off if you ask me.

A common report of LSD is its ability to offer a ‘third-person’ perspective on yourself. To sit outside of yourself as a spectator, rather than exist as the voice inside your head. Viewing life from this perspective can pull you away from self-destructive patterns, open your eyes to new ways of living, and bring about a level of acceptance you may not have experienced before.

To dismiss psychedelic experiences as childish, or without practical medical applications, is to say that reclaiming a firm hold on your life has no value.

All life has value. We should enable everyone to take hold of it again.

Ayahuasca

Ayahuasca is finding its footing now in modern culture. This ‘jungle juice’ has been growing in popularity amongst psychonauts, consciousness explorers, or even just the ever-explorative startup employee on their vacation to South America.

The active ingredient in Ayahuasca is DMT, commonly referred to as the ‘God molecule.’ In a similar fashion to the ibogaine experience we discussed earlier, Ayahuasca teleports users back to critical moments in their lives, often in their formative years of childhood, to come to terms with and face highly traumatic or unresolved issues in their lives.

In being able to approach highly traumatic experiences with love, sensibility, and receptiveness, patients can quite literally change their past.

What does this mean?

Jason Silva does a great job at explaining this. Your past, your personality, your life story, are made up of two things: the memories you have, and the language you use to describe them.

Ayahuasca, and the psychedelic experience in general, allows you to revisit experiences of your past and change the internal dialogue of these moments. In re-framing trauma as a catalyst for growth, or being able to view abuse as misdirected love, patients can heal deep-seated wounds that they could not tackle through traditional therapy.

Why are users able to do this in psychedelic therapy, but not in traditional sessions? Because the experiences are often blocked off, regressed, or the individual is hesitant to reopen these wounds through discussion. They are unable to arrive at an appropriate emotional state to effectively re-frame the problem and re-direct these misplaced emotions. Through no fault of the individual or the therapy structure, this is just a limitation we as a society face.

Psychedelics offer us a solution.

By inducing a state of profound love and tolerance, incredibly damaging experiences can be reframed and addressed at a level significant enough to allow for true therapeutic breakthroughs to occur.

This is the value of Ayahuasca, and this is why it is quickly becoming so popular in Western psychonautic culture. As a result, Ayahuasca is being studied in the treatment of PTSD (post-traumatic stress disorder), persistent negative thought patterns, and chronic depression/suicidal tendencies.

Being able to re-frame personal problems and come to a place of unconditional self-acceptance is a goal of most therapy. Why then, are entheogens that are being proven to allow this, still so taboo in modern and medical culture?

Everyday Improvement: The Magic of Micro-dosing

Closely related to the value of psychedelic therapy are the potential upsides presented by micro-dosing.

 Micro-dosing is the act of taking sub-perceptual doses of a psychedelic substance on a recurring schedule to promote overall vitality and quality of life. You can read more on micro-dosing here.

Just as important, if not more important than the experience itself, is being able to integrate the learning and progress made on the psychedelic journey into everyday life.

One of the incredible potential upsides to psychedelic therapy is that unlike modern pharmacological approaches, the user need not take a daily pill or participate in the experience on a recurring schedule.

One or two single experiences can provide enough revelatory insight to fundamentally change the habits and performance of the patient.

There is, however, a way to derive the profound benefits of the psychedelic experience on a smaller scale in everyday life: micro-dosing.

Simply, micro-dosing is taking a sub-perceptual dose and going about your day as normal. Sub-perceptual means the experience does not cross the threshold of conscious perception. Though you experience the benefits of the substance, you do not ‘feel’ different than your default state.

The benefits of micro-dosing are endless; you can read some of the effects on users here.

Reports from users who have been micro-dosing on a set schedule indicate elevated mood, increased strength, a deeper connection to others, increased endurance, lessened anxiety/fear, and improved communication, just to name a few benefits. Although the direct experience is sub-perceptual, its benefits find their way into everyday life when applied correctly.

Micro-dosing is incredibly important because it can help maintain euthymia or what is known as ‘normal mood’ in the medical community.

In addition to micro-dosing, meditation and mindfulness training can help you maintain a regular, consistent mood. For patients suffering from mental illness, reaching a normal, functional state is the end goal of therapy and treatment, as depression and anxiety are negative deviations from this norm.

Once again, post-experience integration and maintenance are just as important as the experience itself, micro-dosing can be a valuable tool for self-regulation and sustaining the benefits derived from psychedelic therapy.

MDMA: A Notable, Non-Psychedelic Opportunity

As we know, “psychedelic” refers to the altered state of consciousness reached by ingesting or imbibing these different entheogens. MDMA does not fall into the psychedelic category, as it only amplifies existing characteristics, behaviors, and biochemical levels. It is often included by many publications as a psychedelic, but renowned psychedelic explorer James Fadiman, when speaking with Tim Ferriss, offers a succinct differentiation here:

It’s not exactly a psychedelic because you don’t leave your identity behind, but it is the single best way to overcome intractable post-traumatic stress disorder.

Known on the street as the ‘love drug’, MDMA can put users into an unconditional state of love and respect for themselves and for others. Legalization could be a pivotal moment. As we noted with Ayahuasca, this can be instrumental when working to address traumatic experiences, from depression, to rape, to PTSD.

MAPS is also funding research into MDMA, and it is currently moving into Stage 3 trials. Successful Stage 3 trials allow the drug to be administered by credentialed parties, a monumental leap for patients and therapists alike. This is incredibly promising, and users who have participated in the early trial studies came out with remarkable results.

Integrating Psychedelic-Assisted Psychotherapy Into Current Psychiatric Care

We’ve shown that there are multiple entheogens available today that are proving, under scientific scrutiny, that they provide value and effective treatment to patients and situations that have already been deemed ‘treatment-resistant.’

According to the authoritative definition of “Schedule 1 drug,”, these experiences have “no applicable medical value.”

Really?

Do we, as a society, consider the effective treatment of treatment-resistant illnesses lacking any practical value?

At the very least, this should be up for discussion and intelligent debate in academia and modern psychiatric care.

Now, of course, we aren’t advocating to make these available at every corner store in each major city. No, not at all. We are discussing psychedelic therapy, and the use of psychedelics to augment therapeutic treatment when administered by an accredited, accomplished therapist or doctor.

In these environments, studies are showing that psychedelic therapy can be incredibly effective, and in the case of ibogaine, able to accomplish things previously unseen in the medical community.

If it is worth giving psychedelics their well-deserved shot in society, how do we go about doing this? MAPS can point you in the right direction here. What we need is for psychedelics to be re-scheduled away a Schedule 1 substance. This indicates that there are applicable medical values. This is similar to what is happening with marijuana across various states right now.

Additionally, we need entheogens to enter the rigorous scientific study and scrutiny that all other therapeutic treatments and drugs receive.

Why?

We need to validate and replicate the original studies that are happening now and move them along the stages of scientific and medical study to the point where they can be prescribed and administered by the appropriate parties. Just like you can be prescribed Lithium if you are diagnosed with depression, we should move entheogens to the point where you can be prescribed MDMA-assisted psychotherapy if you are diagnosed with PTSD.

To make a tangible impact in these initiatives, you can refer to the resources at MAPS, make a donation, and even consider hosting your own psychedelic dinner!

We must move quickly to bring the medical community up to speed, and to be able to provide patients with the care that could truly save their lives.

Being a superhero isn’t difficult. Sometimes it’s as simple as correcting a mistake that has been made in the past. Helping the past to catch up with the present.

Source:highexistence.com

Learn About the Legal Status of Ibogaine In Your Country


Disclaimer: ibogaine is a potentially illegal substance, and we do not encourage or condone the use of this substance where it is against the law. However, we accept that illegal drug use occurs, and believe that offering responsible harm reduction information is imperative to keeping people safe. For that reason, this guide is designed to ensure the safety of those who decide to use the substance. We do not encourage using this drug outside of a legal or traditional context.

Ibogaine is a psychoactive compound found in several different plants, most commonly the Tabernathe iboga found in parts of Africa. It has been used traditionally by people in certain regions of West Africa for thousands of years, where it is used for its medicinal and psychoactive properties.

In the modern world, ibogaine is becoming popular as an effective treatment of addiction and withdrawal symptoms. It has been used to help people addicted to substances such as opioids, cocaine, amphetamines and alcohol. Treatment centers have started to appear in their hundreds, offering addicts a chance to recover using a natural treatment.

This is how one heroin addict described his treatment with ibogaine:

“As it starts to take effect I feel an intense wave of energy emanating from the centre of my chest that permeates my entire body. This euphoric state also brings me instantaneous relief from the discomfort I was feeling after going without heroin for almost 24 hours.

With my withdrawal symptoms completely gone, I am perplexed by the state of clarity I am in while seeing the most profound stream of visual phenomena. I am also filled with a sense of awe at the potential for a life free of heroin. Emotional memories force me to deal with some of the deep subconscious guilt I have repressed for years.

This powerful state persisted for over 12 hours. After remaining at the clinic for a week I was allowed to return home and over the next six months felt almost no cravings whatsoever.”

Despite ibogaine’s unique potential for the treatment of withdrawal and addiction, its legal status varies worldwide. In this guide, we’ll tell you everything you need to know about the legality of ibogaine, and where you can go for treatment.

WHY IS IBOGAINE ILLEGAL?

Studies have shown that ibogaine is an effective treatment for addiction: one study from 2000 showed that when a single dose (500-800mg) of ibogaine was administered to 27 cocaine- and opioid-addicts, it resulted in a significant decrease of cravings and depressed symptoms. A preliminary observational studyby MAPS also suggests that ibogaine can prevent most patients from relapsing within two months of treatment.

So why then is ibogaine illegal in many countries?

It could be because of its potential harm: high doses can cause heart failure in people with preexisting heart conditions. However it’s most likely ibogaine’s hallucinogenic properties that have made it a victim of Nixon’s war on drugs, much like LSD and magic mushrooms.

If you’re desperate to try ibogaine, or visit a treatment center, there are still many options. Most countries do not specifically prohibit ibogaine, leaving it in a legal grey area for many treatment centers.

Here we group countries based on the legality of ibogaine:

NOTE: This information is curated to be as accurate as possible at the time of writing, but should not be treated as a ‘green light’ to perform potentially illegal activities. Always check your local laws.

COUNTRIES WHERE IBOGAINE IS COMPLETELY ILLEGAL

UNITED STATES

Ibogaine has been a schedule I drug in the US since 1970, and it looks like it won’t change anytime soon. As such it’s illegal to possess or distribute ibogaine – so you won’t find any legal treatment centers in the US.

There’s hope on the horizon – in both New York and Vermont, bills are being considered to encourage the use of ibogaine in research and in the treatment of addiction.

BELGIUM

Ibogaine was banned as early as 1998 in Belgium by Royal Decree, where ibogaine and its isomers are specifically mentioned. Possession and distribution are illegal.

DENMARK

It’s illegal to possess or distribute ibogaine under the Executive Order on Euphoric Substances of 1993; however it’s possible that medical professionals could be given special permission to administer ibogaine in the future.

FRANCE

Ibogaine is illegal to possess and distribute, and has been since 2007. You’ll find it difficult to get treatment here.

HUNGARY

Ibogaine is listed under a law that prevents the distribution of psychoactive substances without a license – you probably won’t find any legal treatment centers here.

IRELAND

Ibogaine probably falls under Ireland’s Psychoactive Substances Act, which makes pretty much everything illegal. However it leaves doors open for potential future research of ibogaine, allowing an exemption for substances that are “medicinal products intended for research and development trials.”

ITALY

Possession or distribution of ibogaine is illegal in Italy, as it was added to the Schedule I list fairly recently.

NORWAY

All tryptamine derivatives are illegal in Norway – and ibogaine will fall into this category. It is probably illegal to possess and distribute.

SWITZERLAND

It’s illegal to possess or distribute ibogaine in Switzerland, as it is specifically listed as a prohibited substance.

SWEDEN

Ibogaine has been illegal to possess or distribute since 1985. The law was brought up for review in 2007, but ibogaine’s status was not changed.

UNITED KINGDOM

Ibogaine technically falls under the UK’s bizarre Psychoactive Substances Act, issued in May 2016, which makes it illegal to produce or distribute “any substance with a psychoactive effect.” Although there are no cases of people being prosecuted for providing ibogaine, the government could absolutely take you to court for doing so.

Thankfully, possession of ibogaine for personal use is still legal; although buying it would be breaking the law.

COUNTRIES WHERE IBOGAINE IS SOMEWHAT PROHIBITED

AUSTRALIA

Ibogaine has been a Schedule IV drug in Australia for several years now, meaning it can’t be distributed without a license – and it doesn’t appear that the government have been handing out any ibogaine licenses…

CANADA

Although ibogaine falls under the category of “Natural Healthcare Products” in Canada, and there are many treatment centers to be found there, its legal status is uncertain. Recently, ibogaine has been seized from several providers, amid concerns over heart risks.

ISRAEL

In 2015, ibogaine was prohibited for distribution under an emergency declaration for 12 months. Since then, it’s unclear what ibogaine’s legal status has become, as information is murky.

COUNTRIES WHERE IBOGAINE IS LEGAL

BRAZIL

In Brazil, ibogaine is legal to possess and distribute. A recent law in Sao Paolo has decreed that ibogaine be administered in a medical environment with adequate protections for the patient.

COSTA RICA

Ibogaine is legal in Costa Rica, and one of the most famous ibogaine treatment centers resides here. However there are some negative reviews out there, and it’s best to do your research before making a choice of treatment center.

GABON

This is the spiritual home of ibogaine. In Gabon, iboga plants are protected by law. However, approval must be given for any export of ibogaine.

MEXICO

Ibogaine is unregulated in Mexico, and is a popular location for treatment centers. Be aware that a good treatment center should always adhere to clinical guidelines and be extremely safety conscious.

NETHERLANDS

There is no specific prohibition of ibogaine in the Netherlands, and there are a variety of treatment centers available.

NEW ZEALAND

Since 2009, ibogaine has been legal by prescription in New Zealand. As such, you can find treatment centers that will offer you ibogaine from a medical professional.

SOUTH AFRICA

Ibogaine is legal in South Africa – but you have to be granted a license to distribute it due to its potential heart risks. We’re not sure how difficult it is to obtain a license.

DON’T SEE A COUNTRY?

Ibogaine is a relatively new drug to the Western world… as such, many countries have no specific laws to deal with ibogaine. If you don’t see a country on our list, it either has no specific prohibition of ibogaine, or we haven’t been able to find one. Always check with your local authority if you’re unsure.

WHAT’S NEXT?

If you’re interested in ibogaine treatment, read our full guide on what to expect at a treatment center. Remember that some centers aren’t legitimate, and make sure your chosen center adheres to clinical guidelines.

If you want to read more general information about ibogaine, read our ultimate guide!

The purpose of this guide is to help you find somewhere you can access ibogaine. Please don’t break the law… and please be careful with ibogaine – it can be harmful if misused.

Ibogaine could end up as an accepted and effective treatment for addiction… but only if we treat it with respect! More stories of irresponsible use and deaths in the media will only delay the approval of ibogaine as a medicine.

Be sensible and be safe!

Source:thethirdwave.com

How Ibogaine Fights Stubborn Prescription Painkiller Addictions.


When he was 13 years old, Jeremy Sutton’s* mother passed away, and he began drinking alcohol to help cope with the trauma. Liquor became cocaine and cocaine became prescription drugs including oxycontin, Hydrocodone and methadone. By the time he turned 18, Sutton was fully addicted to prescription painkillers. His days were designed around getting a fix.

“Opiates were the ones that really stuck with me,” he says, “because they gave me a sort of superpower to deal with the void of being alive.”

While Sutton and a friend who also abused prescription opiates continually made plans to get clean, these plans never stuck. The friend mentioned an alternativeaddiction therapy he had heard called ibogaine, but they had no access to the underground treatment. When he was 25, Sutton checked into rehab. It was here that he met a fellow patient who told him about her experience with ibogaine.

“Obviously this person was in rehab, meaning that they had relapsed,” Sutton says, “but their testimonial was incredible.”

Tabernanthe iboga shrub

Ibogaine is a naturally occurring substance that causes users to experience an intense psychedelic experience that lasts for 24-36 hours, sometimes longer. This treatment clears the brain of addictive cravings while offering deep psycho-spiritual insights. “They made it clear that there’s still a lot of work afterwards,” Sutton says, “but the experience can be profound and can give you the chance to make changes for yourself.”

Derived from the root bark of Tabernanthe iboga shrub, ibogaine is an alkaloid ¾a group of naturally occurring chemical compounds¾ that has been used as a ceremonial sacrament by the Bwiti tribe of Western Central Africa for thousands of years. It has also been used as a treatment for various addictions since roughly 1962, when latemedical researcher and former heroin addict Howard Lotsof, often referred to as the “father of ibogaine” discovered its usefulness as what he called an “addiction interrupter.”

Ibogaine has proven particularly effective in treating opiate addiction, with the majority patients requiring only one session. It not only useful in removing the symptoms of drug withdrawal and reducing drug-cravings, but it has also been shown to help users understand and reverse their drug-using behaviors.

Sutton’s fellow rehab patient gave him the phone number of Beverly Weaver, an ibogaine facilitator at a treatment center in Baja, Mexico. Weaver has guided roughly 200 people through treatments during the past six years. Mexico is home to many such centers, as ibogaine is illegal in the United States, as well as various European countries, Brazil and Australia.

While it’s U.S. classification as a Schedule I drug categorizes ibogaine as a highly addictive substance with no medical properties, there is no scientific evidence that it is habit forming. The Internet offers thousands of anecdotal accounts regarding people successfully overcoming drug addictions via ibogaine. Controlled studies of its medicinal properties have taken place in New Zealand and Canada, the documentary Ibogaine: Rite of Passage chronicles its use, and author Daniel Pinchbeck wrote about traveling to Africa for ceremonial work with Iboga in his book 2002 bookBreaking Open the Head: A Psychedelic Journey into the Heart of Contemporary Shamanism.

In 2012, the then 26-year-old Sutton flew from his native Houston to San Diego, where a representative from the treatment center picked him up and drove him across the border to Mexico. It was his first time leaving the country, and he was to stay for six days at a total cost of $3,000. (“Most places were pretty pricey,” he says. “This one was the cheapest I could find.”)

Before arriving in Mexico, Sutton had gotten an EKG and a liver panel to determine the health of his heart and liver. Such tests are critical, as ibogaine can kill patients with compromised cardiac and liver function. It’s also vital that patients are displaying visible signs of withdrawal such as pulse increase and sweating.

After settling in at the center, Sutton took a walk on the beach and began his treatment at 4pm. He was first given a small dose to test his tolerance. Within an hour, this dose had alleviated his withdrawals.

Beverly Weaver

 

“That’s a really lovely experience, Weaver says, “because in about 45 minutes the withdrawal symptoms go away and the person relaxes. It instills confidence in the person that what’s going to happen is actually going to work.”

Weaver emphasizes that it is essential to have a group of facilitators for each patient, as treatments are long and demanding, often multi-day ordeals. “Not just for sleep relief,” she says, “but energetically, if everyone is together rooting for this person, it has a big impact.” Surrounded by facilitators, Sutton ingested gradually higher doses of ibogaine, administered via capsules, until a predetermined dose based on his weight was reached.

“The first thing I experienced was anxiety and a feeling of electricity going through my whole body. It felt like my heart was beating out of my chest, but they took my blood pressure and everything was in order.”

Sutton then descended into the journey. After taking his third and final capsule, he began losing his motor skills. “I couldn’t lift up my head and was very light sensitive. I noticed a buzzing sound, and it felt like someone had plugged me into an electrical socket. My vision became static, like a static television, when my eyes were shut. I became very nauseous and even more scared. I was starting to lose sensation in my body.”

At this point, however, this period of electricity and frantic thinking to a slowed to a visionary state.

“The vision aspect seemed like I was traveling through the corridors of my own brain. The whole time there was a voice saying, ‘It’s okay; we don’t care what you did. We love you. We’ve always loved you.’ It was very frightening because of the circumstances, but there was always something in the back of my head telling me it was okay, and to relax.

Sutton continues: “The vision tapered down into this experience where I could ask myself any question and get an immediate answer that was crystal clear. Seven hours after I took [the ibogaine], I entered the reflective state and felt like I was getting all of the questions I had answered very clearly.” He laid in contemplative silence for another 12 hours.

21 hours after the ordeal began, Sutton emerged from the journey and found that “there was nothing in my head that was bothering me anymore. I cried a lot too. I remember very specifically that the reason I started crying was because I was not being nice to myself. I realized that I needed to start loving myself, and how much I had not been loving myself up until that point.”

Sutton then drifted to sleep. “I felt like I was floating above my body watching myself lay in bed. I woke up the next day feeling sort of beat up and tired, but in the best place I ever had been in up until that point.”

Tabernanthe iboga bark powder

While there is limited scientific research about how ibogaine works, evidence suggests that the substance resets neurotransmitters that have been programmed for addiction via consistent drug use.

“The simple way I like to explain it,” Weaver says, “is that when you do opiates, they touch receptors in your brain. You do them enough to grow an addiction and you form more of those receptors. When there’s no opiates on those receptors, you’ve got a lot of hungry little mouths yelling ‘I want opiates!’ Iboga goes in and heals all of those hungry little mouths and takes them back to their original state so they’re not hungry anymore.”

Weaver emphasizes that ibogaine does not just treat the addiction, but addresses underlying reasons for the addiction such as abuse and trauma. While profound personal insights are gained, it is vital for users to set themselves up for success after the treatment. “Ibogaine will take care of 49 percent of what you have going on,” Weaver says, “and you’re responsible for the other 51 percent.” Twelve step programs, creative endeavors and overall lifestyle changes are all encouraged.

“It’s not going to make you not an addict anymore,” Sutton says. “It’s going to scramble your brain and reset your head in a way that gives you insight into who you are.

Sutton had struggled with depression and anxiety his entire life, and found that his ibogaine session had alleviated these issues along with his cravings for opiates. After another few days in Mexico, Sutton returned home and began the work of incorporating the lessons ibogaine had taught him. He moved into a new house, cut out unhealthy relationships and focused on his passion for making music.

Four months later, though, his anxiety and depression returned. He found, however, that ibogaine had provided him with new tools to deal with these challenges. “I was able to look back on my experience and saw that my brain operated differently when I was done. I was able to think things through clearer.”

The success rates for ibogaine treatment is still largely unknown, as most of the work is done underground. Weaver says that 70 percent of her patients kick their addictions, and that the overall success rate is 40-50 percent. Comparatively, the success rates for opiate addiction treatment at standard rehab facilities remain low.

Despite its usefulness, Ibogaine is still rare. Weaver believes that on any given night, there are, outside of Africa, 3-5 people in the world doing ibogaine. Still, the small areas of forests in Africa which ibogaine producing trees grow are being harvested at an unsustainable rate. Ibogaine can also be extracted from an African tree called Voacangawhich grows abundantly and is easier to plant.

Sutton’s craving for opiates returned five months after his treatment, and which point he did a second session on his own at home, under the supervision of a family member. Such self-treatment is highly dangerous and not recommended. “I know people who have done it DIY,” Weaver says, “and now they’re dead.”

While Sutton admits that these actions were “horrifying”, they seemed to work. He has been clean for two years and is now in Mexico training to be an ibogaine facilitator.

“The problem that was eating my life up is pretty much gone. Ibogaine was a teacher that told me what needed to be done and to do with the knowledge it gave me what I would.”