Research shows Lion’s mane mushroom can combat dementia and cognitive decline


Currently, there are more than 55 million people who suffer from dementia worldwide, and nearly 10 million new cases of dementia are diagnosed each year. Cognitive decline has become such a pervasive issue in modern society; it has become normalized across the political spectrum. Some of today’s government officials show serious cognitive decline, and even the de facto President of the United States routinely stumbles around in a stupor, taking cues from handlers and mumbling incoherently at times.

Cognitive decline is a serious health issue worldwide, but in many cases, there are ways to reverse the damage, prevent the death of neurons and regenerate neuronal pathways. Lion’s mane mushroom is an important medicinal food that can promote the biosynthesis of nerve growth factor and effectively combat dementia.

Lion’s mane mushroom promotes the biosynthesis of nerve growth factor

A study published in Mycology finds that Lion’s mane mushroom (Hericium erinaceus) synthesizes two very important compounds for nerve growth – Hericenones and erinacines. These compounds are derived from the fruiting body and mycelium of the mushroom. Both compounds promote the biosynthesis of nerve growth factor (NGF) and therefore have value in the prevention and treatment of dementia.

Scientists have isolated two erinacine derivatives and two erinacine diterpenoids (Cyatha-3 and 12-diene with isomer) that promote NGF. Scientists have also demonstrated NGF-stimulating activity from three other compounds in Lion’s mane – Hericenones C, D and E. One of the compounds, 3-Hydroxyhericenone F, showed protective activity against endoplasmic reticulum stress-dependent Neuro2a cell death.

Two other species of the mushroom contained several compounds that promote nerve growth factor. Sarcodon scabrosus (A-F) and Sarcodon cyrneus (A-I, P, Q, J, R, K) all show promise for prevention and treatment of cognitive decline.

Interestingly, both the Hericenones and erinacines are low-molecular weight compounds that cross the blood-brain barrier with ease. The lion’s mane mushroom was designed at the molecular level to positively affect the brain and heal the nervous system, promoting peripheral nerve regeneration and advancing learning abilities into old age.

High blood sugar levels harden arteries, increasing risk of dementia

While there are ways to reverse cognitive decline through medicinal foods, the prevention of dementia should always be approached through a holistic perspective. When treating dementia, it’s equally important to eliminate the chemicals that are promoting cognitive decline. High blood sugar levels are known to harden the arteries, increasing the risk of blockages in the brain. Obstruction of blood flow to the brain can inhibit blood supply to the nerve cells, resulting in impaired brain function.

A study published in the Nutrition Journal found an association between regular consumption of sugary beverages and dementia risk. The study found that free sugars in beverages can increase dementia risk by upwards of 39 percent. The study included a dietary analysis from 186,622 participants from the UK Biobank cohort. The analysis spanned 206 types of food and 32 types of beverages consumed over the course of 10.6 years. The analysis found a correlation between fructose, glucose and sucrose (table sugar) and dementia risk. The free sugars in soda, fruit drinks and milk-based drinks were strongly related to dementia risk, while the sugars in tea and coffee showed minimal risk.

Herbal teas – including but not limited to: green tea, chamomile, lavender and lemon balm – are all wonderful alternatives to sugar-laden drinks. These beverages, when sweetened with plant-based stevia extract, also provide the body with antioxidants, polyphenols and theaflavins that fight free radicals and therefore protect the brain.

Dementia doesn’t have to plague the population and dumb down the people who are running our government and institutions. Advanced learning can continue into old age. Herbal teas can replace sugary beverages in the diet, thus protecting the brain. Medicinal foods like lion’s mane mushroom can heal damaged neurons while promoting new neuron growth.

17 Medicinal plants you can grow indoors year-round


Here is a list of medicinal plants, herbs and spices that you can grow indoors throughout the year. You only need a windowsill, vertical spaces on walls that get enough sunlight or a gardening table set up beneath grow lights to grow these medicinal plants in your home.

These plants are the same ones that you would snip off a sprig or two in an outdoor garden to toss into your casseroles, homemade sauces, salads or soups. Use these plants for their essential oils or to make poultices, salves, teas and tinctures for your medicinal needs.

Basil

Mothers can use basil both before and after giving birth to enhance blood circulation and facilitate the flow of breast milk. Native Americans use basil to treat insect bites and draw out venom from snake bites. Basil can also be used as a natural deworming aid for both humans and animals.

When applied topically, basil can treat minor burns and wounds and help remove warts. It can also help with kidney issues, loss of appetite and stomach spasms, as well as reduce swelling due to fluid retention. Basil can also help relieve cold symptoms.

Chamomile

This medicinal herb can be used to treat ulcers, hay fever, rheumatic discomfort, muscle spasms, minor wounds, muscle and tendon inflammation, menstrual pain, hemorrhoids, insomnia and gastrointestinal disorders.

Chamomile is an excellent natural base ingredient for salves, creams and lotions for dry skin and sunburn.

Chives

Boasting high amounts of vitamins A and C, chives are great for supporting bone and immune health. Chives also contain folate and choline, which can promote good-quality sleep.

Research has found that the phytochemicals in chives, such as ajoene, flavonoids, quercetin and S-allylmercaptocysteine, have potent anticancer properties.

Echinacea

Echinacea is a medicinal plant with brightly colored flowers that can easily brighten up any room in your house. You can use echinacea to make an herbal tea that can prevent and treat respiratory illnesses and boost your immune system.

Garlic

An active base ingredient in many home remedies, garlic is excellent for removing toxins from the body. Garlic can naturally prevent and treat gum disease, respiratory issues and symptoms associated with the common cold and flu, cold sores and yeast infections. It can also help draw out venom from spider bites.

Lavender

Known as a calming and relaxing herb, lavender has been shown to help relieve anxiety and other mood issues. Lavender can also be used as a natural remedy for fungal infections, hair loss, insomnia and skin problems like acne, dry skin, minor wounds and eczema.

Lemon balm

A medicinal herb from the mint family known for its lemon scent, lemon balm is commonly used as a natural medicine for liver and bile issues as well as gastrointestinal problems. When combined with valerian, lemon balm can help relieve restlessness and can even be used as a natural sleep aid. (Related: Lemon balm helps improve gut motility, says research.)

Marjoram

An aromatic herb from the mint family, marjoram has been used to make home remedies for thousands of years. Marjoram has medicinal properties that can be used to treat cough, depression, dizziness, gallbladder problems, muscle and nerve pains, nervous headaches and migraines, runny nose, stomach cramps and many more. (Related: Marjoram can prevent gastric ulcers while showing promise in fighting breast cancer.)

Oregano

Another potent medicinal herb with a long history of use as medicine, oregano can be used as a natural remedy for skin sores, aching muscles, asthma, cramps, diarrhea, indigestion and the common cold. Studies have shown that oregano can also help relieve inflammation, treat bacterial infections, regulate blood sugar and blood cholesterol levels, and fight cancer.

Parsley

A flowering plant whose leaves are widely used as a culinary herb, parsley is a great source of antioxidant vitamins, such as vitamins A and C. It is also rich in vitamin K, which is needed for blood clotting and maintaining strong bones. Parsley boasts powerful antibacterial, antifungal and anticancer properties, the latter of which is thanks to the flavonoids, myricetin and apigenin.

The antioxidant carotenoids in parsley, namely, lutein, beta carotene and zeaxanthin, can also support optimal eye health and prevent age-related macular degeneration. (Related: Parsley is a blood purifying superfood.)

Rosemary

Aside from seasoning food, rosemary can be used to fight halitosis and naturally freshen one’s breath. Because of its beneficial properties, rosemary is often added to all-natural homemade toothpastes and mouthwash solutions. According to studies, rosemary can also enhance brain performance and helps improve digestion, mood and sleep quality. It has natural pain-relieving properties and can also help boost immune function.

Sage

This herb from the mint family can be used to treat bloating, dyspepsia or stomach upset, diarrhea, flatulence, heartburn, hot flashes and memory loss. When used to make tea, sage can also help reduce inflammation, lower blood sugar levels and even fight cancer. Gargling with sage tea is also said to be a good remedy for mouth wounds, sore throats and bad breath.

Spearmint

A pleasantly sweet-tasting herb from the mint family, spearmint is a common ingredient in chewing gums and oral care products. Spearmint is high in antioxidant compounds and is a great natural remedy for digestive issues, such as indigestion and gas. It can also help treat symptoms of hormonal imbalance in women, such as excessive hair growth, or hirsutism.

According to studies, spearmint has antibacterial properties that can help get rid of bacteria in your mouth that cause bad breath. Drinking spearmint tea is also said to help lower blood sugar levels in diabetics.

Stevia

A healthy natural sweetener, stevia, or candyleaf, is an herb from the daisy family that is said to be eight to 150x sweeter than sugar. Stevia is low in calories and has a negligible effect on blood sugar, making it an ideal alternative to table sugar and other unhealthy sweeteners. Studies show that certain glycosides in stevia could help lower blood pressure by helping dilate blood vessels.

Stevia also contains an abundance of antioxidants, such as kaempferol, which has been found to inhibit the growth of pancreatic cancer cells.

Tarragon

Tarragon is an herb from the sunflower family that has long been used in Traditional Asian Medicine. Research suggests that tarragon is an anti-inflammatory, antiepileptic and antipyretic (reduces fever) agent that can also be used to relieve pain naturally. Tarragon is also effective for treating helminthiasis, or infestation of parasitic worms.

Studies show that tarragon also has antioxidant, antitumor, liver-protective and blood sugar-lowering effects. (Related: Tarragon and its many surprising health benefits.)

Thyme

A versatile herb from the mint family, thyme can be used as a substitute for salt in the kitchen. Thyme is well-known for having antiseptic, disinfectant and antibacterial properties, and for its history of use as a food preservative. During World War I, thyme was burned as a fumigator and was even used by ancient doctors to protect them from the Black Plague.

When used for cooking, thyme can help stimulate the appetite and promote good digestion. Its active components, thymol and carvacrol, are often added to mouthwashes, toothpastes, soaps, creams, salves, lotions, liniments, throat lozenges and cold remedies.

Turmeric

Widely known for its many health benefits, turmeric is the spice that gives curry its yellow color. Curcumin, the main active compound in turmeric is a potent anti-inflammatory and antioxidant agent that can help lower your risks of brain and heart disease and cancer. Aptly called the “Golden Spice,” this medicinal herb is traditionally used to heal wounds and treat a variety of ailments, such as rheumatoid arthritis, conjunctivitis, small pox, chicken pox, urinary tract infections and liver issues.

Plants are versatile gifts from Nature that can serve you well either as food or medicine when SHTF. Learn more about useful plants to grow in your home garden at GrowYourMedicine.com.

A Visual Guide to Acupuncture


What Is Acupuncture?

What Is Acupuncture?

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Acupuncture is an age-old healing practice of traditional Chinese medicine in which thin needles are placed at specific points in the body. It’s primarily used to relieve pain but also has been used to treat other conditions. More than 3 million Americans use acupuncture, but it is even more popular in other countries. In France, for example, one in five people has tried acupuncture.

How Acupuncture Works

How Acupuncture Works

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Acupuncture seeks to release the flow of the body’s vital energy or “chi” by stimulating points along 14 energy pathways. Some scientists believe that the needles cause the body to release endorphins — natural painkillers — and may boost blood flow and change brain activity. Skeptics say acupuncture works only because people believe it will, an effect called the placebo effect.

Does Acupuncture Hurt?

Does Acupuncture Hurt?

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Acupuncture needles are very thin, and most people feel no pain or very little pain when they are inserted. They often say they feel energized or relaxed after the treatment. However, the needles can cause temporary soreness.

Acupoint: Low-Back Pain

Acupoint: Low-Back Pain

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If standard treatments don’t relieve your chronic low-back pain, acupuncture may do the job, and two respected medical groups suggest that people in this situation give it a try. One large study found that both actual and “fake” acupuncture worked better than conventional treatments for back pain that had lasted more than three months. The jury’s still out on acupuncture for short-term (acute) pain in the low back.

Acupoint: Headaches

Acupoint: Headaches

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Acupuncture may help relieve migraines or tension headaches. Two large studies found that people receiving acupuncture had fewer days with tension headaches than those receiving conventional care.

Acupoint: Fibromyalgia

Acupoint: Fibromyalgia

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Studies that test how well acupuncture works against the pain of fibromyalgia have had mixed results. Some showed that it provided temporary pain relief, but others did not. A small study by the Mayo Clinic suggested that acupuncture may reduce two other problems of fibromyalgia: fatigue and anxiety. But overall, there’s not enough evidence yet to prove that acupuncture works for fibromyalgia.

Acupoint: Arthritis Pain

Acupoint: Arthritis Pain

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Acupuncture can be a helpful addition to conventional treatment for osteoarthritis, says the National Institute of Arthritis and Musculoskeletal and Skin Diseases. And some of the most promising, early research has shown acupuncture eased arthritis pain in the knee. However, more research is needed to prove without a doubt that it’s effective for osteoarthritis.

Acupoint: Carpal Tunnel Syndrome

Acupoint: Carpal Tunnel Syndrome

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Acupuncture was tested and compared with steroid pills for the hand and arm pain of carpal tunnel syndrome. Researchers in Taiwan gave one group eight acupuncture treatments, over about a month, and those patients reported more relief, for a longer time, than the group taking medicine. While studies like this have been promising, more evidence is still needed to confirm that acupuncture is effective for carpal tunnel syndrome.

Acupoint: Dental Pain

Acupoint: Dental Pain

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Acupuncture provides relief from the pain of tooth extraction or dental surgery, but so does fake acupuncture, some studies show. Still, dental pain is considered by many to be one of the conditions that responds to acupuncture.

Acupoint: Other Pain

Acupoint: Other Pain

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People have tried acupuncture for neck pain, muscle pain, tennis elbow, and menstrual cramps, hoping to avoid medications and their side effects. The World Health Organization lists 28 different conditions that are sometimes treated with acupuncture. In the U.S., a review by the National Institutes of Health called for robust research to verify the promise that acupuncture holds for many different conditions.

A Boost for Pain Medicine

A Boost for Pain Medicine

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Acupuncture may provide added pain relief when it’s used along with pain medicine or another therapy, such as massage. Acupuncture may reduce the need for drugs and improve the quality of life of some people with chronic pain.

Acupoint: Nausea

Acupoint: Nausea

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Acupuncture at the pericardium (P6) acupuncture point on the wrist can reduce the symptoms of nausea and vomiting, even after cancer drug treatments or surgery. Studies compared 10 different acupuncture methods — including needles, electrical stimulation, and acupressure — to drugs that block nausea or vomiting and found the acupuncture treatments worked.

Acupuncture and Cancer Care

Acupuncture and Cancer Care

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Because acupuncture can lessen pain, nausea, and vomiting, it is sometimes used to help people cope with symptoms of cancer or chemotherapy. It also can help manage hot flashes associated with breast cancer. Be sure to talk to your doctor first and seek a practitioner who has experience working with cancer patients.

Acupuncture and Fertility

Acupuncture and Fertility

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Celebrities such as singers Celine Dion and Mariah Carey credited acupuncture — used along with infertility treatments — with helping them get pregnant. A review of medical studies backs up this view, suggesting that acupuncture may boost the effectiveness of fertility treatments. One theory holds that acupuncture helps by reducing stress and increasing blood flow to the ovaries.

Acupuncture to Quit Smoking?

Acupuncture to Quit Smoking?

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Acupuncture has been used for a variety of other conditions, including smoking cessation, insomnia, fatigue, depression, and allergies. The evidence is mixed at best for some uses of acupuncture. For example, acupuncture needles placed in the outer ear to help people stop smoking do not work, studies found.

Acupuncture and Children

Acupuncture and Children

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Acupuncture is generally considered to be safe for children, as long as you are using a licensed practitioner who follows recommended standards of practice. It is primarily used to control pain or nausea and vomiting after surgery or cancer drug treatment. Scientific evidence does not support the use of acupuncture to treat attention deficit hyperactivity disorder.

When to Consider Acupuncture

When to Consider Acupuncture

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Because acupuncture rarely causes more than mild side effects, it is a potential alternative to pain medications or steroid treatments. It is also considered a “complementary” medicine that can be used along with other treatments. It is best to discuss the use of acupuncture with your health care provider.

Acupuncture Risks

Acupuncture Risks

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Although acupuncture is generally safe and serious problems are rare, there are some risks. Needles that are not sterile can cause infection. Make sure that your practitioner uses sterile needles that are thrown away after one use.  In some acupuncture points, needles inserted too deeply can puncture the lungs or gallbladder or cause problems with your blood vessels. That is why it is important to use a practitioner who is well-trained in acupuncture.

Who Shouldn't Use Acupuncture

Who Shouldn’t Use Acupuncture

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People with bleeding disorders or who take blood thinners may have increased risk of bleeding. Electrical stimulation of the needles can cause problems for people with pacemakers or other electrical devices. Pregnant women should talk with their health care provider before having acupuncture. It’s important not to skip conventional medical care or rely on acupuncture alone to treat diseases or severe pain.

Choosing a Practitioner

Choosing a Practitioner

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It is important to receive treatment from someone who has met standards for education and training in acupuncture. States vary in their licensing requirements. There are national organizations that maintain standards, such as the American Academy of Medical Acupuncture (a physician group) or the National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM).  

Acupuncture Variations

Acupuncture Variations

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Several other therapies use a different way of stimulating the acupuncture points. Moxibustion involves the burning of moxa, a bundle of dried mugwort and wormwood leaves, which can then be used to heat the acupuncture needles or warm the skin. Electroacupuncture adds electrical stimulation to the needles. Another recent variation uses laser needles that are placed on (but not in) the skin.

Acupressure vs. Acupuncture

Acupressure vs. Acupuncture

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If you are afraid of needles, you may be able to get much of the same effect from acupressure. Acupressure involves pressing or massaging the acupuncture points to stimulate energy pathways. Scientific comparisons of acupressure and acupuncture are limited, but acupressure has been shown to be effective in reducing nausea and lessening labor pain.

Food GOLD: Turmeric is just as effective as 14 pharma drugs but suffers from NONE of the side effects


Image: Food GOLD: Turmeric is just as effective as 14 pharma drugs but suffers from NONE of the side effects

What if you could replace all the pills in your medicine cabinet with just one herb? Depending on what you take and why, that may be possible with turmeric. Its main component, curcumin, boasts enough health-enhancing properties to keep pharmaceutical execs up at night.

In fact, this herb is so powerful that it has been at the heart of more than 12,000 peer-reviewed biomedical studies. Researchers have found more than 800 different therapeutic and preventive uses for curcumin. Here is a look at just a few of the drugs to which it compares favorably, as outlined by Green Med Info.

Metformin (for diabetes)

Diabetes numbers continue to climb as Americans grapple with obesity, and that means more and more people are taking Metformin – and taking on its scary risks as well. However, a study in the journal Biochemistry and Biophysical Research Community found that curcumin has value in treating diabetes; it is between 500 and 100,000 times more powerful than Metformin when it comes to activating AMPK, which raises glucose uptake. Studies have also shown that it has a 100 percent efficacy rate in preventing those with pre-diabetes from developing full-fledged diabetes.

Lipitor (for cholesterol)

A 2008 study revealed that curcumin compares favorably to atorvastatin, which you may know as Lipitor, when it comes to dealing with the endothelial dysfunction behind atherosclerosis while reducing inflammation and oxidative stress. Other studies have shown that it can impact triglyceride levels, LDL cholesterol, and total cholesterol. While most of the studies so far have been done in animals, it is believed that it could have the same effect in humans, although the right levels have yet to be established.

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Prozac (for depression)

A study in 2011 found that curcumin compares favorably to the antidepressants fluoxetine (Prozac) and imipramine when it comes decreasing depressive behavior. Best of all, it doesn’t carry the serious side effects that Prozac does, which include sleep problems, tremors, headaches, nausea, a lower sex drive, and suicidal ideation. In addition, it’s well-tolerated by patients.

Researchers believe it works on depression by inhibiting monoamine oxidase, the enzyme that has been linked to depression when it’s present in high amounts in the brain. It also raises levels of calmness-inducing serotonin and dopamine.

Oxaliplatin (for chemotherapy)

A study published in the International Journal of Cancer looked at curcumin’s effects in stopping colorectal cell lines from proliferating. The researchers discovered the herb compared favorably to the chemotherapy drug oxaliplatin. Other studies are underway exploring the impact curcumin has on various types of cancer after animal studies showed it could help prevent illnesses like skin, stomach and colon cancer in rats.

Anti-inflammatory medications

Curcumin is also great for inflammation, which is at the root of many chronic illnesses today such as cancer, metabolic syndrome, Alzheimer’s disease, degenerative diseases, and heart disease. A study published in Oncogene identified it as an effective alternative to drugs like ibuprofen, aspirin and naproxen given its strong anti-inflammatory effects, fighting inflammation at the molecular level. Meanwhile, in a study of patients with rheumatoid arthritis, curcumin worked even better than anti-inflammatory drugs.

Curcumin is so effective at addressing such a vast array of conditions that it’s hard to discuss it without sounding like you’re exaggerating. However, turmeric is truly “food gold” and it’s something well worth making a conscious effort to consume more of. You might not be ready to clean out your entire medicine cabinet, but that doesn’t mean you can’t start adding this spice to your food. It pairs well with a variety of dishes, soups, salads, stews, and smoothies; consuming turmeric with fats is ideal, and make sure you add a pinch of pepper to boost its bioavailability.

Sources for this article include:

GreenMedInfo.com

NaturalNews.com

VeryWellHealth.com

Understanding the many benefits of cannabis in cancer treatment


Image: Understanding the many benefits of cannabis in cancer treatment

A cancer diagnosis is both devastating and terrifying. Patients are almost always directed towards conventional cancer treatments like surgery, chemotherapy and radiation, and are made to feel that any other, more “natural” treatments are not only ineffective but dangerous.

The truth is, however, that mainstream cancer treatments wreak havoc on the body, leaving it defenseless against disease and breaking it down at the exact time when it needs to be as strong as possible. With its less than impressive success rate of between 2 and 4 percent, along with its devastating effects on the body, it is unsurprising that three out of every four doctors say they would refuse chemotherapy as a treatment option if they themselves became ill.

While doctors like to promote the idea that there are no treatments scientifically proven to work besides the usual surgery/chemotherapy/radiation regimen, the truth is there is a strong body of evidence that many natural, non-invasive treatments are effective in the fight against cancer. One of the most well-researched and solidly proven of all these natural medicines is cannabis.

The miraculous power of cannabinoids

As noted by Dr. Mark Sircus, writing for Green Med Info, there is no confusion about whether marijuana is an effective cancer treatment. Cannabis has been scientifically proven to kill cancer cells without the devastating and body weakening effects of conventional cancer treatments.

The marijuana plant contains about 113 powerful chemical compounds known as cannabinoids. The most well-known of these compounds are tetrahydrocannabinol (THC) – the chemical that induces marijuana’s “high” – and cannabidiol – a non-psychoactive compound which has been extensively studied as a cure for many diseases.

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These and other cannabinoids are what make marijuana such a potent anti-cancer treatment, as reported by Green Med Info:

Cannabinoids are found to exert their anti-cancer effects in a number of ways and in a variety of tissues.

  • Triggering cell death, through a mechanism called apoptosis
  • Stopping cells from dividing
  • Preventing new blood vessels from growing into tumors
  • Reducing the chances of cancer cells spreading through the body, by stopping cells from moving or invading neighboring tissue
  • Speeding up the cell’s internal ‘waste disposal machine’ – a process known as autophagy – which can lead to cell death

All these effects are thought to be caused by cannabinoids locking onto the CB1 and CB2 cannabinoid receptors. Almost daily we are seeing new or confirming evidence that Cannibinoids can be used to great benefit in cancer treatment of many types.

https://www.brighteon.com/embed/5849729304001

What the science says

Scientific studies published in a host of peer-reviewed journals have confirmed marijuana’s powerful ability to fight breast, lung, ovarian, pancreatic, prostate and other cancers.

A meta-analysis of over 100 published studies, performed by researchers from Germany’s Rostock University Medical Centre, concluded that cannabis both boosts immunity and fights cancer.

The Daily Mail reported:

Scientists are calling for more studies to be done on humans after studying the cancer-fighting effects of chemicals in the drug.

Studies suggest chemicals called phytocannabinoids could stop cancer cells multiplying and spreading, block the blood supply to tumors, and reduce cancer’s ability to survive chemotherapy. …

The new research review admits cannabis has ‘anti-cancer effects’ and says more research needs to be done in real patients to confirm the findings.

It takes real courage to receive a cancer diagnosis and decide not to follow mainstream advice but seek alternative treatments. But even for those who choose to receive conventional cancer treatments like radiation and chemotherapy, cannabis can still be an important part of their overall wellness plan. As Dr. Sircus admonishes, “Every cancer patient and every oncologist should put medical marijuana on their treatment maps.”

Scientists study Canadian medicinal plants to explore natural cures for diabetes


Image: Scientists study Canadian medicinal plants to explore natural cures for diabetes

Diabetes is a complex disease that leads to a wide variety of complications, one of the most common of which is diabetic nephropathy (DN) or kidney damage. A team of researchers from Canada sought to identify natural extracts, found in the eastern James Bay area, with potent anti-apoptotic properties that can prevent kidney cell death characteristic of DN. Their study was published in BMC Complementary and Alternative Medicine.

When it was first recorded in ancient Egypt, diabetes was considered mainly a rare disease. Today, it has exploded into a worldwide epidemic, with about 422 million sufferers on the planet in 2014. The prevalence of the disease is known to be spreading steadily, particularly in mid- to low-income countries.

One of the most dangerous complications of diabetes is DN, which is usually a precursor to kidney failure when left unaddressed. It is just one of the many results of the abnormal apoptotic process that occurs as a result of diabetes.

Apoptosis or cellular death is a natural process that’s essential to the continued balance of the human body. Because of it, old, dysfunctional cells are replaced by new ones. A proof of its importance is how its absence can cause the development of severe diseases, such as cancer.

But as with everything, too much apoptosis is hardly a good thing. In diabetes, the cells go through apoptosis at an abnormal rate. It usually starts with the death of the pancreatic beta cells, the cells responsible for producing the hormone insulin. The insufficiency in insulin results in a jump in blood glucose levels, which leads to more cellular death. Apart from kidney cells, those in the liver and the nervous system are also at a considerable risk.

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DN is one of the most common offshoots of diabetes among the people of the Cree nation in Canada, according to the study’s authors. This has prompted them to look into potential natural treatments that are readily available in the area. They compiled a list of 17 plant species:

  • Balsam fir – Abies balsamea (L.) Mill.
  • Speckled alder – Alnus incana subsp. rugosa (Du Roi) R.T. Clausen
  • Creeping snowberry – Gaultheria hispidula (L.) Muhl.
  • Ground juniper – Juniperus communis L.
  • Sheep Laurel – Kalmia angustifolia L.
  • Tamarack – Larix laricina Du Roi (K. Koch)
  • Common clubmoss – Lycopodium clavatum L.
  • White spruce – Picea glauca (Moench) Voss
  • Black spruce – Picea mariana (P. Mill.) BSP
  • Jack pine – Pinus banksiana Lamb.
  • Balsam poplar – Populus balsamifera L.
  • Labrador tea – Rhododendron groenlandicum (Oeder) Kron and Judd
  • Northern Labrador tea – Rhododendron tomentosum (Stokes) Harmaja subsp. subarcticum (Harmaja) G. Wallace
  • Tealeaf willow – Salix planifolia Pursh
  • Pitcher plant – Sarracenia purpurea L.
  • Showy mountain ash – Sorbus decora (Sarg.) C.K. Schneid.
  • Mountain cranberry – Vaccinium vitis-idaea L.

Extracts were obtained from specific parts of the different plants. The researchers then took cultures of Madin-Darby Canine Kidney (MDCK) cells, which are cells from a cocker spaniel that are used for biological studies involving the kidneys. They induced damage on the MDCK cells by the administration of a hypertonic medium. This particular step was performed in the presence or absence of each of the 17 plant extracts’ maximal nontoxic concentrations. After 18 hours of treatment, the cells were examined to determine the cytoprotective and anti-apoptotic effects of the extracts. The researchers then looked at the effect of the treatment on the activity of caspases-3, -8, and -9, all of which play an important role in apoptosis.

After the test, the researchers identified Gaultheria hispidula and Abies balsamea as having the most potent cytoprotective and anti-apoptotic effects. The said extracts prevented apoptosis by blocking the activity of caspase-9 in the mitochondrial apoptotic signaling pathway.

Curcumin reduces the effects of a high-fat diet


Image: Curcumin reduces the effects of a high-fat diet

Diets high in fat are known as major contributors to many health diseases, such as heart disease, and cancer. Researchers at Jawaharlal Institute of Postgraduate Medical Education and Research in India discovered that taking curcumin supplements minimizes the damage caused by a high-fat diet.

In their study, the researchers looked at the beneficial effects of curcumin on inflammation, oxidative stress, and insulin resistance in high-fat-fed rats. They examined two groups of rats: one group fed with a high-fat diet only and another group given a high-fat diet with 200 milligrams per kilogram (mg/kg) body weight of curcumin every day for 10 weeks.

The researchers measured the rats’ food intake, body weight, and biochemical parameters at the start and the end of the study. After 10 weeks, they also measured the oxidative stress parameters in skeletal muscle and liver triglyceride levels.

The results revealed that the high-fat diet increased the body weight and liver fat. It also increased the levels of plasma glucose, insulin, insulin resistance, total cholesterol, triglycerides, and very low-density lipoprotein cholesterol (VLDL-c), and decreased high-density lipoprotein (HDL) cholesterol.

The high-fat diet also increased inflammation and oxidative stress in skeletal muscles. It also increased liver triglyceride content and caused fat buildup in the liver.

However, the supplementation with curcumin significantly improved these changes. Curcumin supplementation significantly reduced body weight, liver adipose tissue, glucose, insulin, and insulin resistance. In addition, it decreased plasma levels of total cholesterol, triglycerides, VLDL-c, and inflammatory markers, and increased HDL cholesterol. Moreover, it reduced oxidative stress, hepatic triglyceride content, and liver fat deposition.

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With these findings, the researchers concluded that curcumin could improve lipid levels, oxidative stress, inflammation, and insulin resistance caused by a high-fat diet.

Curcumin and turmeric

Curcumin is the active ingredient of the spice called turmeric and is responsible for most of the spice’s health benefits. It takes up about two to eight percent of most turmeric preparations and gives turmeric its distinct color and flavor.  Here are some health benefits of turmeric and curcumin backed up by scientific evidence:

  • Cancer: One of the most notable benefits of turmeric and curcumin is their ability to prevent cancer. Turmeric and curcumin may help prevent cancer by reducing the activity of colon and other cancer cells. A new study published in the Proceedings of the National Academy of Sciences revealed that curcumin inhibits to the DYRK2 enzyme. Inhibiting this enzyme stops protein complexes known as proteasomes that contribute to cancer development. This action interrupts the proliferation of cancer cells, reducing tumors, and slowing cancer’s growth. This is beneficial for preventing proteasome-addicted cancers, such as triple-negative breast cancer and multiple myeloma.
  • Antibacterial: Turmeric and curcumin have powerful antibacterial effects. They have been reported to inhibit the growth of many disease-causing bacteria.
  • Antifungal: Studies have also reported that turmeric and curcumin have antifungal effects. They can disrupt fungal cell membranes and could be used with other fungal medicines for better effect.
  • Diabetes: Turmeric and curcumin can improve blood sugar metabolism and potentially reduce the effects of diabetes in the body.
  • Heart disease: As mentioned in the Indian study, curcumin reduced bad LDL cholesterol and triglycerides. These effects, which were also seen in earlier studies, can cut the risk of heart disease.
  • Liver health: Turmeric and curcumin can also protect the liver from damage caused by oxidative stress.
  • Obesity: Research has shown that turmeric and curcumin may inhibit the inflammatory pathway related to obesity and may help control body fat.
  • Osteoarthritis: Plant compounds in turmeric, including curcumin, can decrease inflammatory markers and relieve osteoarthritis symptoms, such as pain and stiffness.

Use of alternative medicine is associated with absenteeism


An analysis of the 2012 National Health Interview Survey Data examined the associations between self-reported use of various forms of complementary and alternative medicine (CAM) therapies (dietary supplements, mind-body practices) and the number of days missed from job or business in the past 12 months due to illness or injury. Multivariable Poisson regression was used to determine the association between CAM use and absence from work among individuals with one or more chronic disease (n = 10,196).

Over half (54 %) of the study population reported having one chronic disease, while 19 % had three or more conditions. The three most common chronic diseases were high cholesterol (48 %), arthritis (35 %) and hypertension (31 %). More participants used dietary supplements (72 %) while fewer individuals reported using mind-body practices (17 %) in the past twelve months. Over half of individuals reported missing any number of days from job or business due to illness or injury (53 %). Of those who had missed any days from work, 42 % missed one or two days, 36 % missed three to five days, and 23 % missed six days or more.

The authors concluded: Although nearly all individuals who practiced mind-body therapies reported being in good to excellent health, these individuals had a higher rate of absenteeism compared to non-users. Previous studies have shown that many individuals with chronic illness use CAM with the intent of alleviating the symptoms associated with chronic illness but this body of evidence is limited. Further studies are needed to examine the potential effects of these self-managed CAM therapies on the symptoms associated with chronic disease. Additionally, future studies should explore how managing these symptoms through the integration CAM therapies chronic disease management and employee programs could have a positive effect on absence from work, school, and other responsibilities.

How can these finding be interpreted?

The authors offer two possible explanations: Self-administered CAM practices may be more accessible to individuals with chronic disease regardless of socioeconomic status and other demographic factors. Alternatively, CAM use without the advisement of a practitioner may be harmful due to lack of knowledge on proper technique or dosage.

I am sure there are other ways to make sense of these data. How about this interpretation, for instance: CAM-use and absenteeism have in common that they are the things that the ‘worried well’ tend to do. Thus the two phenomena correlate because they are a characteristic of a certain type of consumer.

Yes, I am just guessing, because the data certainly does not give us anything like a conclusive explanation.

Nonetheless, one thing seems to be fairly clear: CAM-use in this population is not a thing that motivates consumers to go to work.

Accumulating evidence suggests curcumin and turmeric can treat psychiatric disorders


Living with a psychiatric disorder can be devastating for both sufferers and their loved ones. Unfortunately, many of the solutions offered by modern medicine do more harm than good while offering little in the way of relief. Thankfully, researchers have discovered that a compound in the popular Indian spice turmeric has the potential to effectively treat psychiatric disorders like bipolar disorder and depression.

You may have heard the fanfare about turmeric’s anti-inflammatory properties, which it gets from a compound within the spice known as curcumin. It has long been used in traditional Chinese medicine and has been gaining popularity in Western medicine in recent years. This polyphenol is being revered for its protective, anti-inflammatory and antioxidant properties, and is being used to help fight cancer and stop the cognitive decline of neurodegenerative disorders like Alzheimer’s. Non-toxic and affordable, it’s showing a lot of promise in helping deal with many of the health problems facing people today.

Image: Accumulating evidence suggests curcumin and turmeric can treat psychiatric disorders

The same anti-inflammatory qualities that make it so good at addressing issues like arthritis can also extend to mood disorders. Not only does it reduce levels of tumor necrosis factor alpha and inflammatory interleukin-1 beta, but it also reduces salivary cortisol concentrations while raising the levels of plasma brain-derived neurotrophic factor.

A study carried out by researchers at Australia’s Murdoch University found that curcumin extracts reduced people’s anxiety and depression scores. They noted that it was particularly effective at alleviating anxiety. Moreover, even low doses of the spice extract were effective in addressing depression. In addition, the researchers found it worked quite well on those with atypical depression, which is a marker of bipolar depression.

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Growing evidence of curcumin’s usefulness in addressing psychiatric disorders

Curcumin has been found in other studies to be just as effective as one of the most popular SSRI antidepressants on the market, Prozac, making it an excellent option for those who wish to avoid the negative side effects of this psychiatric medication. It works by raising levels of dopamine and serotonin, two vital neurotransmitters related to depression. In addition, because depression is believed to be caused by chronic inflammation, it makes sense that curcumin’s ability to reduce inflammation could alleviate depression.

Interestingly, studies have also found that when curcumin is taken either alone or with saffron, it reduces the symptoms of anxiety and depression in those suffering from major depressive disorder. When taken alongside the herb fenugreek, meanwhile, it can reduce fatigue, stress and anxiety in those with extreme occupational stress. Curcumin supplementation has also been shown to significantly improve compulsiveness and memory loss in those with obsessive-compulsive disorder.

It’s also worth noting that curcumin can be taken alongside antidepressants safely; studies have even shown taking the two together can enhance their effectiveness. However, it’s important to keep in mind that antidepressants carry a lot of risks, so it’s worth exploring whether curcumin alone could be enough to alleviate an individual’s depression.

The idea of curcumin helping with mood is supported by a study that was published in the American Journal of Geriatric Psychiatry earlier this year. In that study, researchers found that participants who took curcumin supplements noted mood improvements, and they plan to explore this connection in a study of patients with depression. The researchers expressed optimism that curcumin could be a safe way to provide people with cognitive benefits; they also discovered the spice can improve memory.

Now, researchers are looking for ways to increase curcumin’s bioavailability so that people can enjoy the benefits of this all-star natural treatment. In the meantime, be sure to add black pepper to your dishes when cooking with turmeric or look for curcumin supplements that contain piperine, a black pepper extract, as this boosts its bioavailability.

Yoga reduces pain in people with chronic non-specific lower back pain


Image: Yoga reduces pain in people with chronic non-specific lower back pain

Chronic non-specific lower back pain, a condition affecting thousands of people, is often treated using over-the-counter medicines that can do more harm than good. But did you know that there are safer and more effective natural treatments available for this condition? Studies have suggested that yoga is an effective way to treat chronic non-specific lower back pain.

To evaluate the effects of yoga on chronic lower back pain, researchers from Cochrane conducted a review of yoga and chronic non-specific lower back pain studies. The studies included in the review involved 1,080 participants aged between 24 and 48 who had chronic non-specific lower back pain. The trials were carried out in various parts of the world, including India, the U.K., and the U.S. The researchers also compared the effects of yoga classes that involve back exercises to non-back exercises.

The findings of the review showed that yoga practice may improve symptoms of lower back pain and enhance back-related function compared to other exercises. The researchers also noted that practicing yoga for three months may reduce pain and practicing it for over six months may improve back-related function.

“Our findings suggest that yoga exercise may lead to reducing the symptoms of lower back pain by a small amount, but the results have come from studies with a short follow-up,” said Susan Wieland, lead author of the study from the University of Maryland School of Medicine.

The researchers concluded that practicing yoga may help reduce pain and improve back function in people with chronic non-specific lower back pain. They added that their findings will help people make better choices about their treatment options in the future. (Related: Treating chronic lower back pain with yoga and physical therapy.)

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Other natural treatments for lower back pain that you may have overlooked

There are many natural treatments for lower back pain. However, some of them, like the following, are often overlooked:

  • Release your feel-good hormones: Endorphins, one of the feel-good hormones, can be as effective as any synthetic pain medication. When the body releases these hormones, pain signals are blocked from registering with the brain. They also help relieve stress, anxiety, and depression – all of which are associated with chronic back pain and which often worsen the pain. Aerobic exercise, massage therapy, and meditation are some ways to promote the release of endorphins in the body.
  • Get adequate sleep: Although most people with chronic back pain suffer from sleeping problems, the lack of quality sleep also makes the pain worse. Thus, it is important to address sleeping problems, too.
  • Use cold therapy: Applying cold compress can help reduce lower back pain. It works by reducing inflammation, which is a common cause of back pain. It also acts as a local anesthetic by decelerating nerve impulses, which prevents the nerves from causing pain and spasms.
  • Use heat therapy: Like cold therapy, heat therapy can relieve lower back pain. It works by stimulating blood flow and inhibiting the pain messages being sent to the brain. You can take a hot bath or shower or use a heating pad or hot water bottle.
  • Stretch your hamstrings: Tight hamstrings also contribute to lower back pain as they stress the lower back and sacroiliac joints which, in turn, cause more pain. Try to gently stretch your hamstrings at least twice a day to relieve lower back pain.

 

Sources include:

Cochrane.org

Spine-Health.com