Brain Scans of Dying Man Suggest Life Flashes Before Our Eyes Upon Death


An elderly epilepsy patient unexpectedly died during a brain scan, revealing bursts of activity associated with memory recall, meditation, and dreamin


A man's head with many wires and electrodes attached to his scalp
Doctors were performing an electroencephalogram (EEG) on a patient with epilepsy when he unexpectedly passed away.

New research is revealing what happens in the brain during our final moments of life. When scientists recorded the brainwaves of a dying man, he appeared to go through a sudden flash of memories seconds before and after his heart stopped beating. This first-of-its-kind study suggests we may experience a flood of memories when we die.

In the research published last week in Frontiers in Aging Neuroscience, doctors took brain scans of an 87-year-old Canadian patient with epilepsy. The team was performing a test that detects electrical activity in the brain, called an electroencephalogram (EEG), to learn more about what was happening during his seizures.

The elderly man had an unexpected heart attack and died during the procedure and, in accordance with the patient’s Do-Not-Resuscitate status, the doctors did not attempt any further treatment and the man soon passed away, reports Ed Cara for Gizmodo

Because the EEG machine kept running, doctors got a glimpse into the man’s brain activity at the end of his life. Such scans had never before been captured on a dying individual.

“This is why it’s so rare, because you can’t plan this. No healthy human is going to go and have an EEG before they die, and in no sick patient are we going to know when they’re going to die to record these signals,” study author Ajmal Zemmar, a neurosurgeon at the University of Louisville in Kentucky, says to Insider’s Anna Medaris Miller. 

For roughly 30 seconds before and after the man’s heart stopped beating, the scans showed increased acitivy in parts of the brain associated with memory recall, meditation, and dreaming. Different types of neural oscillations, also called brain waves, are involved in different brain functions. Researchers recorded both high-frequency gamma oscillations as well as slower-frequency theta, delta, alpha, and beta oscillations. Scientists say they were particularly intrigued by the presence of gamma waves, which suggest the man’s brain may have been replaying memories from throughout his life.

“Through generating oscillations involved in memory retrieval, the brain may be playing a last recall of important life events just before we die, similar to the ones reported in near-death experiences,” Zemmar says in a news release. And the patient’s brain activity didn’t immediately stop when he was declared dead. “Surprisingly, after the heart stops pumping blood into the brain, these oscillations keep going,” he tells Insider. “So that was extremely surprising for us to see.”

Because this phenomenon has only been observed in a single case so far, Zemmar and his colleagues caution against assuming brain activity is the same for all people upon death. The patient who died had epilepsy, which can alter gamma wave activity, per Live Science’s Harry Baker.

Despite the limitations of studying a single case, the results built on a 2013 study in rats that reported similar brain activity patterns before and after death, leading some to speculate that memory recall could be a universal experience of dying mammals.

“As a neurosurgeon, I deal with loss at times. It is indescribably difficult to deliver the news of death to distraught family members,” says Zemmar in a press release. “Something we may learn from this research is: although our loved ones have their eyes closed and are ready to leave us to rest, their brains may be replaying some of the nicest moments they experienced in their lives.”

An elderly epilepsy patient unexpectedly died during a brain scan, revealing bursts of activity associated with memory recall, meditation, and dreamin


A man's head with many wires and electrodes attached to his scalp
Doctors were performing an electroencephalogram (EEG) on a patient with epilepsy when he unexpectedly passed away.

New research is revealing what happens in the brain during our final moments of life. When scientists recorded the brainwaves of a dying man, he appeared to go through a sudden flash of memories seconds before and after his heart stopped beating. This first-of-its-kind study suggests we may experience a flood of memories when we die.

In the research published last week in Frontiers in Aging Neuroscience, doctors took brain scans of an 87-year-old Canadian patient with epilepsy. The team was performing a test that detects electrical activity in the brain, called an electroencephalogram (EEG), to learn more about what was happening during his seizures.

The elderly man had an unexpected heart attack and died during the procedure and, in accordance with the patient’s Do-Not-Resuscitate status, the doctors did not attempt any further treatment and the man soon passed away, reports Ed Cara for Gizmodo

Because the EEG machine kept running, doctors got a glimpse into the man’s brain activity at the end of his life. Such scans had never before been captured on a dying individual.

“This is why it’s so rare, because you can’t plan this. No healthy human is going to go and have an EEG before they die, and in no sick patient are we going to know when they’re going to die to record these signals,” study author Ajmal Zemmar, a neurosurgeon at the University of Louisville in Kentucky, says to Insider’s Anna Medaris Miller. 

For roughly 30 seconds before and after the man’s heart stopped beating, the scans showed increased acitivy in parts of the brain associated with memory recall, meditation, and dreaming. Different types of neural oscillations, also called brain waves, are involved in different brain functions. Researchers recorded both high-frequency gamma oscillations as well as slower-frequency theta, delta, alpha, and beta oscillations. Scientists say they were particularly intrigued by the presence of gamma waves, which suggest the man’s brain may have been replaying memories from throughout his life.

“Through generating oscillations involved in memory retrieval, the brain may be playing a last recall of important life events just before we die, similar to the ones reported in near-death experiences,” Zemmar says in a news release. And the patient’s brain activity didn’t immediately stop when he was declared dead. “Surprisingly, after the heart stops pumping blood into the brain, these oscillations keep going,” he tells Insider. “So that was extremely surprising for us to see.”

Because this phenomenon has only been observed in a single case so far, Zemmar and his colleagues caution against assuming brain activity is the same for all people upon death. The patient who died had epilepsy, which can alter gamma wave activity, per Live Science’s Harry Baker.

Despite the limitations of studying a single case, the results built on a 2013 study in rats that reported similar brain activity patterns before and after death, leading some to speculate that memory recall could be a universal experience of dying mammals.

“As a neurosurgeon, I deal with loss at times. It is indescribably difficult to deliver the news of death to distraught family members,” says Zemmar in a press release. “Something we may learn from this research is: although our loved ones have their eyes closed and are ready to leave us to rest, their brains may be replaying some of the nicest moments they experienced in their lives.”

Using Brain Scans and Lifestyle to Resolve Mental Illness


For those facing mental health issues, there are powerful remedies besides the one-size fits all drug treatments

Brain SPECT imaging of Type 6 ADHD/ADD also known as "Ring of Fire" is characterized by abnormally increased activity in multiple brain regions. (Photo courtesy of Amen Clinic)

Brain SPECT imaging of Type 6 ADHD/ADD also known as “Ring of Fire” is characterized by abnormally increased activity in multiple brain regions.

When people ask me how brain imaging can impact mental health care, I tell them about one of my favorite patients named Jarrett. As a little boy, he was hyperactive, restless, impulsive, highly vocal, and wouldn’t pay attention. His behavior was so disruptive that other kids didn’t want to play with him, and he didn’t have a single friend. Diagnosed with ADHD as a preschooler, Jarrett seemed to be on a bad path, and his parents were distraught.

Jarrett’s parents took him to five different doctors who prescribed five types of stimulant medications for ADHD. But none of them worked. In fact, they made things worse by triggering extreme mood swings and severe rages that frightened his siblings. Jarrett’s conduct got so out of control that one physician suggested antipsychotic medication. That was the last straw for his mother, who decided to bring Jarrett to see us at Amen Clinics, which I founded over 30 years ago.

In the past three decades, we have been using brain SPECT (single-photon emission computed tomography) imaging—a well-researched tool that measures blood flow and activity in the brain—on tens of thousands of patients with emotional, behavioral, learning, and cognitive problems. Our database of over 225,000 brain scans relating to behavior shows us that as psychiatrists, we are not dealing with “mental” health issues but rather brain health issues that steal people’s minds. And this one idea changes everything.

When we scanned Jarrett’s brain, it clearly showed significant overactivity in a pattern we call the “Ring of Fire.” His brain was working way too hard. It’s no surprise that the stimulant medications weren’t working. Using stimulants on an overactive brain is like pouring gasoline on a fire. Our published research shows that stimulants make this brain pattern worse 80 percent of the time.

We took a very different approach to treating Jarrett. Combining nutritional supplements to calm his overactive brain with a host of brain-healthy daily lifestyle habits and parent training led to significant improvements in Jarrett’s behavior. At school, his grades went up and he started making the honor roll. The rages disappeared. And he finally started making friends. Today, Jarrett is doing well in college and training to be a firefighter because, as he says, “On somebody’s worst day, I want to make it better.” If no one had ever looked at his brain, Jarrett could have been doomed to stay on a very unhealthy path.

How Do You Know Unless You Look?

Did you know that psychiatry remains the only medical specialty that virtually never looks at the organ it treats? Cardiologists look at the heart, oncologists scan the body for cancerous tumors, and orthopedists take x-rays of bones. Psychiatrists guess. If you’re struggling with anxiety, depression, ADHD, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), or other issues, no one will look at your brain.

That’s insane!

The repercussions of “brainless psychiatry” have contributed to alarming statistics:

  • 25 percent of Americans are taking at least one prescription mental health medication
  • More than 337 million antidepressant prescriptions were given in 2021
  • 27 percent of doctor visits result in a prescription for benzodiazepines (anxiety medication)
  • According to a large epidemiological study in Archives of General Psychiatry, 51 percent of the U.S. population will struggle with a mental health issue at some point in their lives.

Things have only gotten worse due to the pandemic. These statistics seem dire, but there is hope.

What Brain Imaging Reveals About Mental Health

Brain imaging is changing the way we think about mental health. There is a growing understanding in the field of psychiatry that mental health is really brain health. And experts, such as the journal Radiology, have validated the use of brain imaging in psychiatry. In 2021 the Canadian Association of Nuclear Medicine endorsed brain SPECT imaging for the assessment of:

  • Neuropsychiatric disorders, such as ADHD, bipolar disorder, depression, OCD, and PTSD
  • Suspected dementia, such as Alzheimer’s disease, frontal temporal lobe dementia, vascular dementia, and mild cognitive impairment
  • Traumatic brain injury
  • Substance abuse
  • Strokes

To clarify, brain imaging is not used as a stand-alone diagnostic tool. The data must be analyzed in conjunction with other elements of a comprehensive psychiatric evaluation, such as a person’s history, neuropsychological testing, and more.

Some of the ways brain SPECT imaging can be beneficial is by helping identify the root causes of psychiatric symptoms, and by prompting psychiatrists to ask better questions to get to the source of a person’s symptoms.

To put it simply, SPECT scans reveal 3 important things:

  • Regions of the brain that work well
  • Regions of the brain that are working too hard, indicating abnormally high blood flow
  • Regions of the brain that are not working hard enough, indicating low blood flow

In general, when the brain is working too hard or not working hard enough, it is associated with a wide range of emotional, behavioral, and cognitive health problems.

Our brain-imaging work at Amen Clinics has also shown that mental health problems are not single or simple disorders. They all have multiple types and each require targeted treatment plans. Giving everyone with ADHD, for example, the same treatment may help some people, but can make others worse. Think of how the standard ADHD treatment exacerbated Jarrett’s symptoms. Knowing which type you have can help find the most effective treatment.

You Can Change Your Brain and Change Your Life

One of the most exciting things we have learned from our brain-imaging work is that you’re not stuck with the brain you have. You can make it better. You can literally change your brain and change your life for the better.

Every day, your brain is changing. Either it is getting healthier and helping you think, feel, and act better, or it is getting unhealthier and making you feel sad, mad, anxious, forgetful, or stressed. In large part, it depends on your daily thoughts, decisions, diet, supplements, and habits.

11 Risk Factors That Harm The Brain

Based on our brain imaging work and more than 30 years of clinical practice, we have identified the 11 major risk factors that harm the brain and steal your mind. We developed the mnemonic BRIGHT MINDS to help you remember them.

  • B is for blood flow. Blood flow delivers oxygen and other nutrients to your body and brain and carries away waste products. Low blood flow seen on brain SPECT imaging is associated with many psychiatric symptoms and is the #1 brain imaging predictor of Alzheimer’s disease.
  • R is for retirement and aging. When you stop learning, your brain starts dying.
  • I is for inflammation. Chronic inflammation is like a constant internal fire that harms your organs and can destroy your brain.
  • G is for genetics. Brain health issues clearly run in families, but genes are not a death sentence. They should be a wake-up call to take brain health seriously.
  • H is for head trauma. Mild traumatic brain injuries—even bumps or blows to the head that don’t cause you to black out—are a major cause of psychiatric symptoms, but few people know it because psychiatrists don’t look at the brain.
  • T is for toxins. Exposure to environmental toxins—such as alcohol or marijuana, or those found in household cleaners and personal care products—has been linked to numerous psychiatric symptoms.
  • M is for mental health. Having untreated ADHD, depression, or other conditions can be devastating and is associated with increased risk of divorce, job failure, and general unhappiness.
  • I is for infections. Infectious illnesses, such as COVID-19, Lyme disease, and streptococcus (strep throat), are a major cause of psychiatric and cognitive problems that few medical professionals recognize. A 2022 study in BMJ found that people who have had COVID—even mild cases—are 60 percent more likely to struggle with mental health problems. And one of the study’s authors said that more than 2.8 million new cases of psychiatric illness can be linked to COVID infections.
  • N is for neurohormone issues. When hormones are imbalanced, it can lead to a host of psychiatric symptoms. For example, research shows that hypothyroidism is associated with depression, memory loss, attention problems, and mental sluggishness.
  • D is for diabesity. The word “diabesity” combines diabetes and obesity, both of which decrease the size and function of your brain, according to research. One study found that obesity is also associated with greater risk of depression, bipolar disorder, addictions, and more.
  • S is for sleep. Your brain needs sleep to stay healthy, but 60 million Americans aren’t getting adequate shut-eye. Research shows that over time, sleep problems can lead to a higher risk of depression, ADHD, panic attacks, brain fog, memory problems, and dementia.

11 Daily Habits That Boost Brain Power

The exciting news is that you can boost your brain health and mental well-being by adopting the following daily habits.

Boost blood flow. Engaging in regular exercise (anything you love that gets your heart pumping) and practicing meditation or prayer have been shown to improve blood flow.

Engage in new learning. To keep your brain active, learn something new. Take piano lessons, play a new sport, or learn a foreign language. And don’t retire! A 2021 study found that holding off on retirement decreases the rate of cognitive decline.

Reduce inflammation. Avoid pro-inflammatory foods (such as sugar, refined carbohydrates, trans fats, artificial sweeteners, and gluten). Instead, consume prebiotics (apples, beans, cabbage, psyllium, artichokes, onions, leeks, asparagus, and root veggies) and probiotics (fermented foods like kefir, kombucha, and unsweetened yogurt, or supplements).

Know your family history. Find out if any of your relatives have had any emotional, behavioral, or cognitive problems. You may also want to consider genetic testing.

Protect your head. Wear a helmet while biking or skiing, hold the handrail when you walk downstairs, and don’t text while you’re walking or driving. If you’ve had a head injury, consider hyperbaric oxygen therapy (HBOT), which uses pure oxygen to accelerate the healing process. A brain SPECT imaging study in Plos One involving 56 people with mild traumatic brain injuries found that treatment with HBOT resulted in improved brain activity levels as well as significant improvements in cognitive function and quality of life.

Limit exposure to toxins. To avoid toxins, quit smoking and limit alcohol consumption. Use an app like Think Dirty to check if your personal care products or household cleaners contain toxins and eliminate those items from your home.

Seek treatment for mental health issues. Seeking treatment is not a sign of weakness, it is a sign of strength. Look for a professional who understands that brain health is the key to mental health and uses the least toxic, most effective treatments.

For example, neurofeedback is a non-invasive, interactive treatment that allows you to strengthen and retrain your brain to enhance emotional, behavioral, and cognitive health. A 2016 review of scientific studies on neurofeedback shows its benefits include better memory, improved focus, decreased anxiety, enhanced mood, less anger, reduced stress, and more.

If you’re struggling with the effects of past emotional trauma, a psychotherapeutic technique called EMDR (eye movement desensitization and reprocessing) can have a powerful effect. A 2014 review of 24 randomized controlled trials found that EMDR can be beneficial in the treatment of emotional trauma and adverse life experiences. What makes this therapy even more appealing is that some evidence shows it is more effective and produces results more rapidly than traditional psychotherapy.

Shore up your immune system and treat infections. Boost your vitamin D level and lower your stress. One of my favorite evidence-based immunity-boosting stress-management techniques is laughter. Watch a comedy on TV.

If you’re struggling with fatigue, brain fog, and other issues related to long COVID, you may want to consider HBOT, which was described earlier. A 2021 study on 10 people with long COVID found that 10 sessions of HBOT produced improvements in fatigue, cognition, attention, executive function, information processing, and verbal function. Other clinical trials are underway to assess the benefits of HBOT for long COVID.

Support your hormones. To promote healthy hormones, avoid smoking, chronic stress, processed food, caffeine, and alcohol.

Eat a brain-healthy diet. Eat organic colorful fruits and vegetables (especially berries and leafy greens), sustainably raised fish and meat, low-glycemic foods, high-fiber foods, nuts and seeds, and healthy fats (avocados, coconut oil, olive oil). As I like to tell my patients, only love foods that love you back!

In addition, it’s critical to take nutritional supplements to support optimal brain health. I recommend that everyone take a multivitamin, omega-3 fatty acids, probiotics for gut health, and vitamin D (if your levels are low). Other supplements with scientific evidence include GABA to help calm anxious brains; saffron to boost moods; rhodiola, ashwagandha, and green tea extract to support focus and energy; and phosphatidylserine to support memory.

Make sleep a priority. Adopt a good sleep hygiene program—such as keeping your bedroom dark, cool, and quiet, and try hypnosis to promote more restful sleep.

When you learn to love and care for your brain every day, it helps you boost your mood, memory, focus, mental clarity, and sense of calm. Are you ready to make brain and mental health a daily practice?

Brain scans of one-handed people are completely changing our understanding of the brain.


“The implications, if this interpretation is correct, are massive.”

 Scans taken of people born with only one hand have revealed areas of the brain typically associated with the ‘missing hand’ are taken over by other parts of the body, radically changing our thinking on how our brain operates.

Whether it’s an arm or a foot, other limbs seem to fill in for the missing hand. In other words, rather than being responsible for specific parts of the body, as previously thought, different sections of the brain could be responsible for specific functions.

 The team of researchers say their findings could prompt a fundamental shift in our understanding of the brain and the way it’s able to manage certain tasks with different parts of the body.

“Scientifically, I think one way to put our results in context is to say, what if the hand area is not the hand area per se, but just the part of the brain in charge of function ‘normally’ carried by that hand?” says one of the researchers, Tamar Makin from University College London in the UK.

The study looked at 17 people born with just one hand and 24 two-handed controls, who were video recorded while carrying out five everyday tasks, including handling money and wrapping presents.

Participants were also asked to move different parts of their body, and all the while their brains were being scanned via MRI.

The researchers found that when congenital one-handers used something to replace their missing hand in a task – like an elbow or a foot – that body part lit up the same part of the brain as the missing hand would in a two-handed person.

We should point out that this is just a small sample of people, and the scientists aren’t certain why this is happening, but they have a hypothesis: that areas of the brain aren’t organised by body parts, but by what those body parts are doing.

 “If true, this means we’ve been misinterpreting brain organisation based on body part, rather than based on function,” says Makin.

“It’s kind of mind-blowing for me to think we could have been getting this wrong for so long. The implications, if this interpretation is correct, are massive.”

For now, it’s still just a hypothesis, but it’s a hypothesis that could lead to a rethink on how our brain is organised. Maybe the brain is more flexible and adaptable than we thought.

There are already studies that indicate people with missing senses, such as sight, can recruit parts of the brain usually responsible for other tasks, such as performing calculations or processing language.

We have understood for some time that the brain can rewire itself following a limb amputation to make use of the real estate, sometimes causing painful ‘phantom sensations‘, but this new discovery could potentially cast existing research in a new light.

With about 86 billion neurons firing in all directions, the brain is an incredibly complex organ that scientists are still trying to properly understand.

While we’re making progress in smarter AI, working out the fundamentals of copying human movement in robots continues to prove tricky – by the age of two, humans can control their hands better than the most advanced robots.

With that in mind, the findings could eventually help us to understand how the brain compensates for the loss of a limb, and improve prosthetic replacements which could be attached to the right part of the brain and controlled with our minds.

This new research could help push all those efforts further forward.

“If we, as neuroscientists, could harness this process, we could provide a really powerful tool to better healthcare and society,” adds Makin.

“By learning how this occurs spontaneously in one-handers, we can get a handle on what we might be able to achieve.”

Source: Current Biology.

How Machine Learning May Help Tackle Depression


By detecting trends that humans are unable to spot, researchers hope to treat the disorder more effectively.

Depression is a simple-sounding condition with complex origins that aren’t fully understood. Now, machine learning may enable scientists to unpick some of its mysteries in order to provide better treatment.For patients to be diagnosed with Major Depressive Disorder, which is thought to be the result of a blend of genetic, environmental, and psychological factors, they have to display several of a long list of symptoms, such as fatigue or lack of concentration. Once diagnosed, they may receive cognitive behavioral therapy or medication to help ease their condition. But not every treatment works for every patient, as symptoms can vary widely.

Recently, many artificial intelligence researchers have begun to develop ways to apply machine learning to medical situations. Such approaches are able to spot trends and details across huge data sets that humans would never be able to, teasing out results that can be used to diagnose other patients. The New Yorker recently ran a particularly interesting essay about using the technique to make diagnoses from medical scans.

Similar approaches are being used to shed light on depression. A study published in Psychiatry Research earlier this year showed that MRI scans can be analyzed by machine-learning algorithms to establish the likelihood of someone suffering from the condition. By identifying subtle differences in scans of people who were and were not sufferers, the team found that they were able to identify which unseen patients were suffering with major depressive disorder from MRI scans with roughly 75 percent accuracy.

Perhaps more interestingly, Vox reports that researchers from Weill Cornell Medical College are following a similar tack to identify different types of depression. By having machine-learning algorithms interrogate data captured when the brain is in a resting state, the scientists have been able to categorize four different subtypes of the condition that manifest as different mixtures of anxiety and lack of pleasure.

Not all attempts to infer such fine-grained diagnoses from MRI scans have been successful in the past, of course. But the use of AI does provide much better odds of spotting a signal than when individual doctors pore over scans. At the very least, the experiments lend weight to the notion that there are different types of depression.

The approach could be just one part of a broader effort to use machine learning to spot subtle clues related to the condition. Researchers at New York University’s Langone Medical Center, for instance, are using machine-learning techniques to pick out vocal patterns that are particular to people with depression, as well as conditions like PTSD.

And the idea that there may be many types of depression could prove useful, according to Vox. It notes another recent study carried out by researchers at Emory University that found that machine learning was able to identify different patterns of brain activity in fMRI scans that correlated with the effectiveness of different forms of treatment.

In other words, it may be possible not just to use AI to identify unique types of depression, but also to establish how best to treat them. Such approaches are still a long way from providing clinically relevant results, but they do show that it may be possible to identify better ways to help sufferers in the future.

In the meantime, some researchers are also trying to develop AIs to ensure that depression doesn’t lead to tragic outcomes like self-harm or suicide. Last month, for instance, Wired reported that scientists at Florida State University had developed machine-learning software that analyzes patterns in health records to flag patients that may be at risk of suicidal thoughts. And Facebook claims it can do something similar by analyzing user content—but it remains to be seen how effective its interventions might be.

Source:www.technologyreview.com

Yale Neuroscientists Can Now Determine Human Intelligence Through Brain Scans.


Article Image
The human connectome. By Andreashorn – Own work, CC BY-SA 4.0.

Do you feel like you were born to do something? There is just a certain skill like playing an instrument or sport, or a certain subject, like math, which you naturally excel in? It might have to do with the way your brain is wired. Different people have different aptitudes. The repositories for these lie in different parts of the brain and, as scientists are learning more and more, in the connectome or the connections between regions.

Today, neuroscientists can determine one’s intelligence through a brain scan, as sci-fi as that sounds. Not only that, it’s only a matter of time before they are able to tell each individual’s set of aptitudes and shortcomings, simply from scanning their brain. Researchers at Yale led the study. They interpreted intelligence in this case as abstract reasoning, also known as fluid intelligence. This is the ability to recognize patterns, solve problems, and identify relationships. Fluid intelligence is known to be a consistent predictor of academic performance. Yet, abstract reasoning is difficult to teach, and standardized tests often miss it.

Researchers in this study could accurately predict how a participant would do on a certain test by scanning their brain with an fMRI. 126 participants, all a part of the Human Connectome Project, were recruited. The Human Connectome Project is the mapping of all the connections inside the brain, to get a better understanding of how the wiring works and what it means for things like intellect, the emotions, and more. For this study, researchers at Yale put participants through a series of different tests to assess memory, intelligence, motor skills, and abstract thinking.

They were able to map the connectivity in 268 individual brain regions. Investigators could tell how strong the connections were, how active, and how activity was coordinated between regions. Each person’s connectome was as unique as their fingerprint, scientists found. They could identify one participant from another with 99% accuracy, from their brain scan. Yale researchers could also tell whether the person was engaged in the assessment they were taking or if they were aloof about it.

Emily Finn was a grad student and co-author of this study. She said, “The more certain regions are talking to one another, the better you’re able to process information quickly and make inferences.” Mostly, fluid intelligence had to do with the connections between the frontal and parietal lobes. The stronger and swifter the communication between these two regions, the better one’s score in the abstract thinking test. These are some of the latest regions to have evolved in the brain. They house the higher level functions, such as memory and language, which are essentially what make us human.

Axonal nerve fibers in the real brain, by jgmarcelino from Newcastle upon Tyne, UK

Yale researchers believe that by learning more about the human connectome, they might find novel treatments for psychiatric disorders. Things like schizophrenia vary widely from one patient to the next. By finding what’s unique to a particular patient, a psychiatrist can tailor treatment to suit their needs. Understanding one’s connectome could give insight into how the disease progresses, and if and how the patient might respond to certain therapies or medications. But there are other uses which we may or may not feel comfortable with.

For instance, your child could have their brain scanned to track them at school, according to study author Todd Constable. It might be used to say whether or not a candidate is qualified for a job or should pursue a certain career. Brain scans could tell who might be prone to addiction, or what sort of learning environment a student might flourish in. School curriculum could even be changed on a day-to-day basis to fit student’s needs. And the dreaded SAT might even be shelved too, in favor of a simple brain scan.

Peter Bandettini is the chief of functional imaging methods at the National Institute of Mental Health (NIMH). He told PBS that barring ethical issues, brain scans could someday be used by employers to tell which potential candidate possesses desirable aptitudes or personality traits, be they diligent, hardworking, or what-have-you. Richard Haier, an intelligence researcher at UC Irvine, foresees prison officials using such scans on inmates to tell who might be prone to violence.

We may even someday learn how to augment human intelligence from studies such as this. It’s important to remember that intelligence research is still in its infancy. Yet, according to Yale scientists, we are moving in this direction.

Some fear a Minority Report-like misuse of said technology. Neuroethicist Laura Cabrera at Michigan State University enumerated for WIRED her concerns. What if insurance companies denied coverage based on such a scan, due to a tendency toward addiction or some other predisposition. Of course, just because someone has a higher risk of something, doesn’t mean they will develop it. Without proper guidelines in place and oversight, we could quickly see banks, schools, universities, and other institutions taking part in “neuro-discrimination.” Strong laws will have to be put in place to defend against misuse.

There are limits to what we now know about the human connectome that have yet to be overcome. For instance, we can only look at the connections as they are now. We don’t know how they form or develop over time. And fluid intelligence is merely one type out of several different kinds. We are still far from applying such technology in the real world. But the potential is there.

To learn more about the Human Connectome Project, click here:

Watch the video.URL:

Source:http://bigthink.com

 

Yale Neuroscientists Can Now Determine Human Intelligence Through Brain Scans.


Article Image
The human connectome. By Andreashorn

Do you feel like you were born to do something? There is just a certain skill like playing an instrument or sport, or a certain subject, like math, which you naturally excel in? It might have to do with the way your brain is wired. Different people have different aptitudes. The repositories for these lie in different parts of the brain and, as scientists are learning more and more, in the connectome or the connections between regions.

Today, neuroscientists can determine one’s intelligence through a brain scan, as sci-fi as that sounds. Not only that, it’s only a matter of time before they are able to tell each individual’s set of aptitudes and shortcomings, simply from scanning their brain. Researchers at Yale led the study. They interpreted intelligence in this case as abstract reasoning, also known as fluid intelligence. This is the ability to recognize patterns, solve problems, and identify relationships. Fluid intelligence is known to be a consistent predictor of academic performance. Yet, abstract reasoning is difficult to teach, and standardized tests often miss it.

Researchers in this study could accurately predict how a participant would do on a certain test by scanning their brain with an fMRI. 126 participants, all a part of the Human Connectome Project, were recruited. The Human Connectome Project is the mapping of all the connections inside the brain, to get a better understanding of how the wiring works and what it means for things like intellect, the emotions, and more. For this study, researchers at Yale put participants through a series of different tests to assess memory, intelligence, motor skills, and abstract thinking.

They were able to map the connectivity in 268 individual brain regions. Investigators could tell how strong the connections were, how active, and how activity was coordinated between regions. Each person’s connectome was as unique as their fingerprint, scientists found. They could identify one participant from another with 99% accuracy, from their brain scan. Yale researchers could also tell whether the person was engaged in the assessment they were taking or if they were aloof about it.

Emily Finn was a grad student and co-author of this study. She said, “The more certain regions are talking to one another, the better you’re able to process information quickly and make inferences.” Mostly, fluid intelligence had to do with the connections between the frontal and parietal lobes. The stronger and swifter the communication between these two regions, the better one’s score in the abstract thinking test. These are some of the latest regions to have evolved in the brain. They house the higher level functions, such as memory and language, which are essentially what make us human.

Axonal nerve fibers in the real brain, by jgmarcelino from Newcastle upon Tyne, UK

Yale researchers believe that by learning more about the human connectome, they might find novel treatments for psychiatric disorders. Things like schizophrenia vary widely from one patient to the next. By finding what’s unique to a particular patient, a psychiatrist can tailor treatment to suit their needs. Understanding one’s connectome could give insight into how the disease progresses, and if and how the patient might respond to certain therapies or medications. But there are other uses which we may or may not feel comfortable with.

For instance, your child could have their brain scanned to track them at school, according to study author Todd Constable. It might be used to say whether or not a candidate is qualified for a job or should pursue a certain career. Brain scans could tell who might be prone to addiction, or what sort of learning environment a student might flourish in. School curriculum could even be changed on a day-to-day basis to fit student’s needs. And the dreaded SAT might even be shelved too, in favor of a simple brain scan.

Peter Bandettini is the chief of functional imaging methods at the National Institute of Mental Health (NIMH). He told PBS that barring ethical issues, brain scans could someday be used by employers to tell which potential candidate possesses desirable aptitudes or personality traits, be they diligent, hardworking, or what-have-you. Richard Haier, an intelligence researcher at UC Irvine, foresees prison officials using such scans on inmates to tell who might be prone to violence.

We may even someday learn how to augment human intelligence from studies such as this. It’s important to remember that intelligence research is still in its infancy. Yet, according to Yale scientists, we are moving in this direction.

Some fear a Minority Report-like misuse of said technology. Neuroethicist Laura Cabrera at Michigan State University enumerated for WIRED her concerns. What if insurance companies denied coverage based on such a scan, due to a tendency toward addiction or some other predisposition. Of course, just because someone has a higher risk of something, doesn’t mean they will develop it. Without proper guidelines in place and oversight, we could quickly see banks, schools, universities, and other institutions taking part in “neuro-discrimination.” Strong laws will have to be put in place to defend against misuse.

There are limits to what we now know about the human connectome that have yet to be overcome. For instance, we can only look at the connections as they are now. We don’t know how they form or develop over time. And fluid intelligence is merely one type out of several different kinds. We are still far from applying such technology in the real world. But the potential is there.

Watch the video. URL:https://youtu.be/2nzLxAoUuts

Is Hypnosis All in Your Head? Brain Scans Suggest Otherwise


Hypnosis has become a common medical tool, used to reduce pain, help people stop smoking and cure them of phobias.

The magician Byrne Perkins, left, using hypnosis on Herbert Easley in 1952. Researchers at Stanford have found that some parts of the brain function differently under hypnosis than during normal consciousness.

 But scientists have long argued about whether the hypnotic “trance” is a separate neurophysiological state or simply a product of a hypnotized person’s expectations.
 The study published on Thursday by Stanford researchers offers some evidence for the first explanation, finding that some parts of the brain function differently under hypnosis than during normal consciousness.
The study was conducted with functional magnetic resonance imaging, a scanning method that measures blood flow in the brain. It found changes in activity in brain areas that are thought to be involved in focused attention, the monitoring and control of the body’s functioning, and the awareness and evaluation of a person’s internal and external environments.
“I think we have pretty definitive evidence here that the brain is working differently when a person is in hypnosis,” said Dr. David Spiegel, a professor of psychiatry and behavioral sciences at Stanford who has studied the effectiveness of hypnosis.
 Functional imaging is a blunt instrument and the findings can be difficult to interpret, especially when a study is looking at activity levels in many brain areas.
Still, Dr. Spiegel said, the findings might help explain the intense absorption, lack of self-consciousness and suggestibility that characterize the hypnotic state.
He said one particularly intriguing finding was that hypnotized subjects showed decreased interaction between a region deep in the brain that is active in self-reflection and daydreaming and areas of the prefrontal cortex involved in planning and executing tasks.
That decreased interaction, Dr. Spiegel said, suggested an explanation for the lack of self-consciousness shown by hypnotized subjects.

“That’s why the stage hypnotist can get a football coach to dance like a ballerina without feeling self-conscious about what he’s doing,” Dr. Spiegel said. He added that it might also explain, at least in part, why hypnosis is an effective tool in psychotherapy for getting people to look at a problem in a new way.

 The researchers screened more than 500 potential subjects for susceptibility to hypnosis and then compared brain activity in 36 who scored very highly on tests measuring susceptibility to hypnosis and 21 who had very low scores on those tests.
Brain activity during hypnosis was also compared with activity during resting periods and during a memory task, for both high and low susceptibility groups.

In the hypnosis task, the subjects were guided through two guided procedures for hypnotic inductions: in one, they were instructed to imagine a time when they felt happiness; in the other, they were told to remember or imagine a vacation.

All the subjects were asked in the study to rate how deeply hypnotized they felt during the inductions.

Although some researchers continue to argue that hypnosis is a state produced by people’s expectations, not by biology, Dr. Spiegel said, “At some point, I just think it becomes a kind of self-fulfilling word game.”

“I see hypnosis as a kind of app you haven’t used on your cellphone,” he said. “It’s got all kinds of capacity that people are just figuring out how to use, but if you haven’t used it the phone doesn’t do that.”

Brain scans of microcephalic babies suggest Zika disrupts development.


Brain scans of 23 Brazilian infants with the birth defect microcephaly showed widespread and severe abnormalities suggesting that Zika may invade fetal nerve cells and disrupt brain development.

The findings, published on Wednesday in a letter to the New England Journal of Medicine, are based on a large trove of computed tomography, or CT images, done in infants whose mothers are believed to have had Zika infections during pregnancy.

Therapist Rozely Fontoura holds Juan Pedro, who has microcephaly, in Recife, Brazil March 26, 2016. REUTERS/Paulo Whitaker

The study included researchers from Brazil’s Northeastern state of Pernambuco, such as Dr. Ana van der Linden of the Instituto de Medicina Integral, who were among the first to sound the alarm about increasing cases of microcephaly in Brazil thought to be linked with Zika infections.

Microcephaly is a typically rare birth defect marked by unusually small head size, signaling a problem with brain development. Brazil is investigating thousands of cases of microcephaly and has confirmed more than 940 cases to be related to Zika infections in the mothers.

Scientists in the study ran several tests on the mothers to try to rule out other possible causes of microcephaly, including toxoplasmosis, cytomegalovirus, parovirus, HIV and rubella. All were all negative. All of the mothers had symptoms during their pregnancies – such as fever and rash – that were consistent with Zika infections. Testing on spinal fluid from seven of the infants was positive for Zika antibodies.

The researchers did CT scans when the babies were between three days and five months old. All showed signs of brain calcification, which is suggestive of brain inflammation. Many of the babies had other abnormalities, including brain swelling, disruptions in brain folds, underdeveloped brain structures and abnormalities in myelin, which forms protective sheaths on nerve fibers.

Researchers said the findings were consistent with a study published last month testing lab dishes full of nerve stem cells similar to those in the brains of human fetuses. They showed that the Zika virus was able to easily infect these cells, stunting their growth.

Researchers said evidence from the brain scans suggests the abnormalities occurred from a disruption of brain development, rather than a destruction of brain cells.

According to the World Health Organization, there is a strong scientific consensus that Zika can cause microcephaly, although conclusive proof may take months or years.

Brain Scans Finally Prove That Dogs Choose Humans As Their Family Over Their Own Breed


Dogs love their human friends as much as we love our pooches. The phrase “a dog is a man’s best friend” has been used, since time immemorial, to exemplify the relationship the two share. And now justifying this claim, and proving exactly why dogs choose humans as their own over other dogs, is a new study that scanned the dogs’ brains with MRI machines.

Dogs get MRI scans

Borbala Ferenczy

Scientists who study animal cognition at Emory University, trained dogs to lie still while their brains could be mapped. Since dogs navigate the world through their noses, they were presented with smells of humans and other dogs (known and unknown), to gain an insight into how exactly humans excite these mutts more than their own canine family.

Dogs get MRI scans

Borbala Ferenczy

1. Dogs and smells

Dogs

wonderfulmachine

Aroma of their owners activate the very ‘reward center’ of the dogs’ brains, also known as the caudate nucleus. Keeping aside all other smells, the dogs always prioritize the waft of their humans over anyone or anything else.

2. Dogs and sounds

Dogs

themes.com

Validating an earlier experiment done in Budapest, the recent studies also establish how dogs become excited when they hear joyful sounds. The reward center of their brains gets activated, making them feel excited and happy.

3. Dogs and hugs

Dogs

flickr

Dogs are also the only “non-primate” beings to look directly into their human’s eyes. Not only this, dogs are the “only domesticated animals” to seek protection from humans when they are down. Their running straight into our arms is a proof of that.

4. Dogs and emotions

Dogs

zoozoo

The emotional attachment that dogs develop with humans is reciprocated in equal measures by the humans. When scientists mapped the brain activity of mothers who have both had a baby and a dog for over two years, they found the same response from their reward centers – one of love and bonding.

5. Dogs and instincts

Dogs

mrwallpaper

While humans often misread the ‘hangdog look’ as a signifier of a dog’s guilt, most of the times our intuition about what’s really going on inside our pet’s head turns out to be correct. We can also agree that it holds true for all the times when our dogs sense our inner thoughts to perfection.

Science is the best. I am running off to give my little furry best friend a tight hug. 🙂

Criminal Minds Are Different From Yours, Brain Scans Reveal


The latest neuroscience research is presenting intriguing evidence that the brains of certain kinds of criminals are different from those of the rest of the population.

While these findings could improve our understanding of criminal behavior, they also raise moral quandaries about whether and how society should use this knowledge to combat crime.

The criminal mind

In one recent study, scientists examined 21 people with antisocial personality disorder – a condition that characterizes many convicted criminals. Those with the disorder “typically have no regard for right and wrong. They may often violate the law and the rights of others,” according to the Mayo Clinic.

Brain scans of the antisocial people, compared with a control group of individuals without any mental disorders, showed on average an 18-percent reduction in the volume of the brain’s middle frontal gyrus, and a 9 percent reduction in the volume of the orbital frontal gyrus – two sections in the brain’s frontal lobe.

Another brain study, published in the September 2009 Archives of General Psychiatry, compared 27 psychopaths — people with severe antisocial personality disorder — to 32 non-psychopaths. In the psychopaths, the researchers observed deformations in another part of the brain called the amygdala, with the psychopaths showing a thinning of the outer layer of that region called the cortex and, on average, an 18-percent volume reduction in this part of brain.

“The amygdala is the seat of emotion. Psychopaths lack emotion. They lack empathy, remorse, guilt,” said research team member Adrian Raine, chair of the Department of Criminology at the University of Pennsylvania, at the annual meeting of the American Association for the Advancement of Science in Washington, D.C., last month.

University of Pennsylvania criminologist Adrian Raine
University of Pennsylvania criminologist Adrian Raine
Credit: U Penn

In addition to brain differences, people who end up being convicted for crimes often show behavioral differences compared with the rest of the population. One long-term study that Raine participated in followed 1,795 children born in two towns from ages 3 to 23. The study measured many aspects of these individuals’ growth and development, and found that 137 became criminal offenders.

One test on the participants at age 3 measured their response to fear – called fear conditioning – by associating a stimulus, such as a tone, with a punishment like an electric shock, and then measuring people’s involuntary physical responses through the skin upon hearing the tone.

In this case, the researchers found a distinct lack of fear conditioning in the 3-year-olds who would later become criminals. These findings were published in the January 2010 issue of the American Journal of Psychiatry.

Neurological base of crime

Overall, these studies and many more like them paint a picture of significant biological differences between people who commit serious crimes and people who do not. While not all people with antisocial personality disorder — or even all psychopaths — end up breaking the law, and not all criminals meet the criteria for these disorders, there is a marked correlation.

“There is a neuroscience basis in part to the cause of crime,” Raine said.

What’s more, as the study of 3-year-olds and other research have shown, many of these brain differences can be measured early on in life, long before a person might develop into actual psychopathic tendencies or commit a crime.

Criminologist Nathalie Fontaine of Indiana University studies the tendency toward being callous and unemotional (CU) in children between 7 and 12 years old. Children with these traits have been shown to have a higher risk of becoming psychopaths as adults.

“We’re not suggesting that some children are psychopaths, but CU traits can be used to identify a subgroup of children who are at risk,” Fontaine said.

Yet her research showed that these traits aren’t fixed, and can change in children as they grow. So if psychologists identify children with these risk factors early on, it may not be too late.

“We can still help them,” Fontaine said. “We can implement intervention to support and help children and their families, and we should.”

These brain scans of psychopaths show a deformation in the amygdala compared to non-psychopaths, from a study by Adrian Raine and colleagues.
These brain scans of psychopaths show a deformation in the amygdala compared to non-psychopaths, from a study by Adrian Raine and colleagues.
Credit: Yang et al./Archives of General Psychiatry

Neuroscientists’ understanding of the plasticity, or flexibility, of the brain called neurogenesis supports the idea that many of these brain differences are not fixed. [10 Things You Didn’t Know About the Brain]

“Brain research is showing us that neurogenesis can occur even into adulthood,” said psychologist Patricia Brennan of Emory University in Atlanta. “Biology isn’t destiny. There are many, many places you can intervene along that developmental pathway to change what’s happening in these children.”

Furthermore, criminal behavior is certainly not a fixed behavior.

Psychologist Dustin Pardini of the University of Pittsburgh Medical Center found that about four out of five kids who are delinquents as children do not continue to offend in adulthood.

Pardini has been researching the potential brain differences between people with a past criminal record who have stopped committing crimes, and those who continue criminal behavior. While both groups showed brain differences compared with non-criminals in the study, Pardini and his colleagues uncovered few brain differences between chronic offenders and so-called remitting offenders.

“Both groups showed similar results,” Pardini said. “None of these brain regions distinguish chronic and remitting offenders.”

Ethical quandaries

Yet even the idea of intervening to help children at risk of becoming criminals is ethically fraught.

“Do we put children in compulsory treatment when we’ve uncovered the risk factors?” asked Raine. “Well, who decides that? Will the state mandate compulsory residential treatment?”

What if surgical treatment methods are advanced, and there is an option to operate on children or adults with these brain risk factors? Many experts are extremely hesitant to advocate such an invasive and risky brain intervention — especially in children and in individuals who have not yet committed any crime.

Yet psychologists say such solutions are not the only way to intervene.

“You don’t have to do direct brain surgery to change the way the brain functions,” Brennan said. “You can do social interventions to change that.”

Fontaine’s studies, for example, suggest that kids who display callous and unemotional traits don’t respond as well to traditional parenting and punishment methods such as time-outs. Instead of punishing bad behavior, programs that emphasize rewarding good behavior with positive reinforcement seem to work better.

Raine and his colleagues are also testing whether children who take supplemental pills of omega-3 fatty acids — also known as fish oil — can show improvement. Because this nutrient is thought to be used in cell growth, neuroscientists suspect it can help brain cells grow larger, increase the size of axons (the part of neurons that conducts electrical impulses), and regulate brain cell function.

“We are brain scanning children before and after treatment with omega-3,” Raine said. “We are studying kids to see if it can reduce aggressive behavior and improve impaired brain areas. It’s a biological treatment, but it’s a relatively benign treatment that most people would accept.”

‘Slippery slope to Armageddon’

The field of neurocriminology also raises other philosophical quandaries, such as the question of whether revealing the role of brain abnormalities in crime reduces a person’s responsibility for his or her own actions.

“Psychopaths know right and wrong cognitively, but don’t have a feeling for what’s right and wrong,” Raine said. “Did they ask to have an amygdala that wasn’t as well functioning as other individuals’? Should we be punishing psychopaths as harshly as we do?”

Because the brain of a psychopath is compromised, Raine said, one could argue that they don’t have full responsibility for their actions. That — in effect — it’s not their fault.

In fact, that reasoning has been argued in a court of law. Raine recounted a case he consulted on, of a man named Herbert Weinstein who had killed his wife. Brain scans subsequently revealed a large cyst in the frontal cortex of Weinstein’s brain, showing that his cognitive abilities were significantly compromised.

The scans were used to strike a plea bargain in which Weinstein’s sentence was reduced to only 11 years in prison.

“Imaging was used to reduce his culpability, to reduce his responsibility,” Raine said. “Yet is that not a slippery slope to Armageddon where there’s no responsibility in society?”