CKD: Lower Salt Intake May Reduce Heart Risks.


A diet with restricted salt intake may help to reduce the risk for cardiovascular disease in patients with chronic kidney disease (CKD), as well as the risk for CKD progression, according to an article published online November 7 in the Journal of the American Society of Nephrology.

Emma J. McMahon, PhD candidate, University of Queensland, Australia, and colleagues conducted a double-blind, placebo-controlled randomized crossover trial involving 20 adult patients with stage 3 to 4 CKD. In the phase I portion of the LowSALT CKD study, the researchers evaluated the effects of high vs low sodium intake on several physiological measures, including ambulatory blood pressure, protein excretion, and body fluid status.

The researchers counseled patients to eat a low-sodium (1080 – 1440 mg/day) diet during the 1-week run-in period of the 6-week study, they then randomly assigned patients to either a high-sodium or low-sodium diet. Those on the high-sodium diet had a goal of 1080 to 1440 mg/day plus 2160 mg/day from a slow-release tablet. Those on the low-sodium diet had a goal of 1080 to 1440 mg/day plus a placebo capsule. Patients crossed over after an intermediate washout week.

The investigators found a mean reduction of 9.7/3.9 mm Hg in blood pressure in patients on the low-salt diet compared with the high-salt diet. The reductions were consistent during a 24-hour period with no significant difference between daytime and nighttime measurements. Researchers also found that patients had reductions in fluid volume, body weight, and protein in the urine while on the low-salt diet.

“If these findings are transferable to the larger CKD population and shown to be sustainable long-term, this could translate to markedly reduced risk of cardiovascular events and progression to end-stage kidney disease, and it could generate considerable health-care savings,” senior author Katrina J. Campbell, PhD, from Princess Alexandra Hospital, Queensland, said in a news release.

“These are clinically significant findings, with this magnitude of blood pressure reduction being comparable to that expected with the addition of an anti-hypertensive medication and larger than effects usually seen with sodium restriction in people without CKD,” McMahon noted in the release. “If maintained long-term, this could reduce risk of progression to end-stage kidney disease — where dialysis or transplant is required to survive — by 30%.”

“This study is salient because few intervention studies have evaluated dietary sodium reduction in patients with CKD, write Cheryl A.M. Anderson, PhD, MPH, and Joachim H. Ix, MD, both from the University of California San Diego School of Medicine, in an accompanying editorial. “The evaluation of other outcomes in addition to BP is an additional strength of the trial.”

Australia bans sunbeds in every state in a bid to slash deaths from skin cancer.


Australia is to ban all commercial sunbeds in a bid to slash skin cancer rates.

Every state has now either banned or is planning to outlaw commercial sunbeds due to the country having some of the highest skin cancer rates in the world.

The condition is responsible for more than 2,000 deaths and 80 per cent of all new cancer diagnoses.

Every Australian state has now either banned or is planning to outlaw commercial sunbeds due to the country having some of the highest skin cancer rates in the worldEvery Australian state has now either banned or is planning to outlaw commercial sunbeds due to the country having some of the highest skin cancer rates in the world

On Sunday, the Queensland government announced a total ban on commercial sunbeds by December 31 next year.

The state’s 44 solarium operators will be paid $1,000 AUD (£600) in compensation for each tanning bed – a total cost of $160,000 (£9,540), Sky News reported.

The move came after other states – New South Wales, Victoria, South Australia, Tasmania and the ACT all took steps to regulate or ban sunbed use.

Following the Queensland announcement, Dr Kim Hames, health minister of Western Australia – the only remaining state left to act – announced he was also preparing documents to ban sunbeds.

Cases of malignant melanoma - the deadliest skin cancer - have doubled in the last decadeCases of malignant melanoma – the deadliest skin cancer – have doubled in the last decade

He told Fairfax Radio: ‘There is no doubt about the increased risk of cancer – so I think the chances are (a ban in WA) won’t be far away.’

‘I have to take it to cabinet, but if it happens it will happen in the next three months,’ Dr Hames told Fairfax radio.

Research has shown that people who have ever used a sunbed are 20 per cent more likely to  develop melanoma later in life, compared to people who had never used one.

And those who started using sunbeds before the age of 35 were 87 per cent more likely to develop melanoma compared to people who have never used a sunbed.

Cases of malignant melanoma – the deadliest skin cancer – have doubled in the last decade, according to figures from Cancer Research UK.

Around 13,000 Britons are diagnosed with the illness each year and it causes 2,800 deaths.

The Australian crackdown comes after Brazil outlawed tanning beds, along with U.S. states such as Vermont and California. In the UK, people under 18 are banned from using sunbeds.

Tanning beds became increasingly popular among young Australians around 15-20 years ago. But numbers have fallen dramatically since a similar ban for under 18s was introduced.

Sara Osborne, Cancer Research UK’s head of policy, said: ‘It’s encouraging to see the Australian Government tackling this important issue and it will be interesting to see the response in other countries.

The Australian crackdown comes after Brazil outlawed tanning beds, along with U.S. states such as Vermont and California. In the UK, people under 18 are banned from using sunbedsThe Australian crackdown comes after Brazil outlawed tanning beds, along with U.S. states such as Vermont and California. In the UK, people under 18 are banned from using sunbeds

‘The evidence linking sun bed use and skin cancer is very clear. Overexposure to UV rays from the sun or sunbeds is the main cause of skin cancer, including malignant melanoma – the most serious form of the disease – which sadly kills around six people every day in the UK.

‘Cancer Research UK urges people not to use sunbeds for cosmetic reasons. The charity was involved in the successful campaign to introduce a ban on under-18s using them and is now asking the Government to give local authorities the power to license any businesses that provide sunbeds and to inform users of the health risks.

Australian boffins brew up a hydrating beer.


Quenching a hard earned thirst with a big cold beer just got better for you – thanks to the work of some clever Queensland scientists.

Researchers from Griffith University‘s health institute have discovered that it is possible to substantially improve the hydrating effects of the amber ale.

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By adding electrolytes, an ingredient commonly found in sports drinks, and reducing the alcohol content researchers found that beer could become even more refreshing. And the best news for beer drinkers is that the taste of the modified brews didn’t change.

As part of the study, the researchers modified two commercial beers, one regular strength and one light beer. They then gave them to volunteers who had worked up a sweat after exercise to test fluid recovery.

Associate Professor Ben Desbrow said the light beer which had been combined with electrolytes provided the best level of hydration.

“Of the four different beers the subjects consumed, our augmented light beer was by far the most well retained by the body, meaning it was the most effective at re-hydrating the subjects,” he said.

Professor Desbrow said it was more effective to tell people how to minimise dehydration than telling them not to drink.

“If you’re going to live in the real world, you can either spend your time telling people what they shouldn’t do, or you can work on ways of reducing the danger of some of these socialised activities,” he said.

The new super beer paves the way for products to be developed that could reduce the likelihood of the dreaded hangover; so it’s a triumphant day for beer drinkers everywhere.

Source: http://www.smh.com.au