Medical ultrasonography

Comparing methods for evaluating Mullerian structures.

Posted by

0


Disorders of sex development (DSD) are a group of congenital conditions with atypical development of chromosomal, gonadal, or anatomic sex [, ]. It is estimated that the incidence of genital anomaly is 2 in 10,000 live births [, ], although some degree of male undervirilization or female…

Abstract

Purpose   The diagnosis of children with disorders of sex development (DSD) requires a karyotype, different biochemical and radiological investigations in the context of a multidisciplinary team. The aim of this study was to compare the diagnostic accuracy of laparoscopy (L) versus ultrasonography (US) in the assessment of children with complex DSD.
Methods   We retrospectively examined the theatre database searching for children with DSD who underwent laparoscopic surgery from 1999 to 2011. The medical and radiological records were reviewed.
Results   Eighteen patients were identified. Age at diagnosis ranged from birth to 14 years (mean 2.5 years). There were seven patients with 46XY dysgenetic testicular DSD (4 mosaic Turner, 3 mixed gonadal dysgenesis), seven patients with 46XY non-dysgenetic testicular DSD (4 persistent Mullerian duct syndrome, 2 complete androgen insensitivity syndrome, one unknown), two patients with ovotesticular DSD, one patient with 46XX DSD (congenital adrenal hyperplasia) and one patient with 46XY DSD complete sex reversal. Fifteen underwent ultrasonography prior to laparoscopy. Both modalities identified Mullerian structures in seven (47 %) patients, in one (7 %) patient US and L confirmed the absence of Mullerian structures, while in six (40 %) patients there was discordance, with US failing to visualize pelvic Mullerian structures. In the last patient with 46XY non-dysgenetic testicular DSD, the rectum was thought to be a dilated uterus on ultrasonography.
Conclusions   Pelvic ultrasonography failed to identify Mullerian structures in 40 % of patients with complex DSD. On the contrary, laparoscopy allowed excellent visualization of pelvic structures and gonads in children with complex DSD.

Source: http://www.getinsidehealth.com

 

First Ultrasound Imaging System Approved for Dense Breast Tissue .

Posted by

0


The FDA approved the first ultrasound system for imaging dense breast tissue on Tuesday. The somo-v Automated Breast Ultrasound System (ABUS) is intended for use in women with dense tissue who’ve had a negative mammogram and no symptoms of breast cancer.

In a clinical study of some 200 women with dense breast tissue, cancer was detected significantly more often when board-certified radiologists reviewed mammograms along with somo-v ABUS images than when they reviewed mammograms alone.

Source: FDA