100,000 British invited to post their genomes online.


A hundred thousand British volunteers could have their genetic information available to anyone in the world. Some scientists warn the Personal Genome Project may be a step too far for confidentiality.

The project is US-based and allows people to find out more about their genetic profiles, plus contribute to advances in medical science. Volunteers from America and Canada have already joined the project.

To participate, people have to be at least 18 years old and understand the risks and benefits when they apply online. They fill out a detailed health history and complete a 19-page consent form.

They will later get their genome analysis and have a four-week “cooling off” period before deciding if they want their data to go online, Reuters reported.

Discovering the role of the genetic code may help to battle complex diseases like cancer, or discover why some people have special traits like perfect musical pitch, according to Stephan Beck, professor of medical genomics at the UCL Cancer Institute and director of the British project.

The project aims to sequence 50 people’s genomes, the 3 billion chemical pairings that make up human DNA, in the first year of the project.

The volunteers will be warned of possible implications, as there are a few challenges that the project faces, and the main one is ethical.

The genome gives a person’s entire genetic information, and revealing the data could also disclose the presence of yet undetected illnesses or elevated risks of developing conditions like Alzheimer’s.

Another controversy is that an open-access DNA database could trigger fraudulent use of people’s information.
Scientists are also cautious about the project.

“GeneWatch UK’s view is that people should think twice before agreeing to share their genome openly. Remember your DNA contains a unique genetic code which can be used to track you and identify your relatives. Stored online it will be accessible to police, security and border agencies based in any country,” Helen Wallace, of GeneWatch British non-profit group specializing in genetics, told The Guardian.

The UK is the first country to join the research which was launched by George Church of Harvard Medical School in 2005. He believes breakthroughs in medicine aren’t possible without “big datasets about individuals and that is what the Personal Genome Project offers.”

In the US, Church managed to find 3,000 volunteers for his project, and several hundred more in Canada, of those only 200 genomes have been sequenced.

The scientist also forecast that genome sequencing will speed up as the cost continues to fall dramatically – it has come down from $1 billion 20 years ago to a few thousand dollars nowadays.

A total of 25,000 human genomes were sequenced around the world in various projects, but just fractions are available to the public.

Help Stop These Thousands Of Genetically Modified Insects From Being Released.


Thousands of Genetically Modified (GM) insects developed by British scientists are set to be released into fields across Europe as an alternative to chemical pesticides. Granted, pesticides have been responsible for jeopardizing human health, damaging the environment and killing millions of bees and other insects, but is the proper solution manufacturing genetically modified insects?

The idea is to release a large number of GM olive flies that will be used to kill off wild pests that damage the crop. The company responsible for their manufacture and release is Oxitec.  They plan to release GM male olive flies that would naturally mate with the females, ultimately resulting in the death of female offspring at the larvae or maggot stage. The thought is that this would lead to a reduction in the olive fly population, which would allow the trees to produce fruit without the need for chemical sprays.

Oxitec has applied to Spanish regulatory authorities for permission to carry out a netted field trial of its GM insects. If the trial is successful, more trials will be carried out in Greece and Italy- the company also eventually hopes to be able to use the GM insects in British fields as well.

Our approach is aimed not only at controlling the olive fly, but also to avoid harming other species. By using our form of genetic sterility our flies are designed to eliminate the pest and not to stay in the environment. – Oxitec’s Dr Martha Koukidou (1)

In my view the use of GM insects to eradicate this pest is a necessary step towards achieving zero pesticide use. Critics of this technology who warn of danger to health and environment are scaremongering. European agriculture is facing some severe challenges. The burden of agricultural pests is ever present while the number of control approaches is shrinking in the face of insecticide resistance and de-registration of existing chemical treatments. To survive and prosper, European farming will need to evaluate and embrace new solutions and new technologies which are effective, sustainable and safe. If approved, this evaluation will be an important step to brining an exciting new approach to the farmers who need it- Hadyn Parry, Oxitec chief executive  (1)

Supporters of the GM insects, like Oxitec, claim that those who oppose the idea are simply fear mongering. This is currently the same response from the big biotech giants to opposers of genetically modified foods. Recently, we have found out that opponents of genetically modified foods have been correct with their concerns, as multiple studies have surfaced over the past couple of years that indicated GMOs can be very harmful to the environment, as well as pose multiple risks to human health.

It’s no different with these genetically modified insects, mosquitos to be exact, they’ve already been released into the public without a proper risk assessment.

Dr Helen Wallace, director of GeneWatch UK, warned:

Releasing Oxite’s GM fruit flies is a deeply flawed approach to reducing numbers of these pests, because large numbers of their offspring will die as maggots in the fruit. Not only does this fail to protect the crop, millions of GM fruit fly maggots will enter the food chain where they could pose risks to human health and the environment. Oxitec’s experiments should not go ahead until rules for safety testing and plans for labelling and segregation of contaminated fruits have been thoroughly debated and assessed. If these issues are ignored, growers could suffer serious impacts on the market for their crops.(1)

So what does this mean for animals that eat these flies as part of their routine diet? Or what about the humans that then eat these animals? Plans to commercialize GM insects would result in millions of GM insects being released onto field crops, including olives, tomatoes, citrus fruits, cabbages and cotton. Millions of GMO mosquitoes have already been released in experiments intended to reduce transmission of the tropical disease dengue fever, did you know about this? The release of GM insects are covered by laws and regulations that cover the release of genetically modified organisms (GMOs), however, there is no specific regulatory process for GM insects anywhere in the world. (2) (3)

Regulatory decisions on GM insects in Europe and around the world are being biased by corporate interests as the UK biotech company Oxitec has infiltrated decision-making processes around the world. The company has close links to the multinational pesticide and seed company, Syngenta. Oxitec has already made large-scale open releases of GM mosquitoes in the Cayman Islands, Malaysia and Brazil and is developing GM agricultural pests, jointly with Syngenta. (2)(3)

The public will be shocked to learn that GM insects can be released into the environment without any proper oversight. Conflicts of interest should be removed from all decision making processes to ensure the public have a proper say about these plans – Dr Helen Wallace, Director of GeneWatch UK (4)

The use of GM technologies is controversial. Some organizations such as GeneWatch UK and EcoNexus fear that reliance on high-tech solutions like genetic modification detracts from more effective but poorly deployed measures to combat the harm caused by insects. These are the companies we need to hear more about because they are the ones that directly monitor the use of genetic technologies. Environmental NGOs like Greenpeace suggest that GM insects could have unintended and wide ranging impacts on the environment and human health due to the complexity of ecosystems and the high number of unknown factors which make risk assessment difficult. These companies have raised a number of concerns which include (2):

·         New insects or diseases may fill ecological niche left by the insects suppressed or replaced, possibly resulting in new public health or agricultural problems

·         The new genes engineered into the insects may jump into other species, a process called horizontal transfer, causing unintended consequences to the ecosystem

·         Releases would be impossible to monitor and irreversible, as would any damage done to the environment

A briefing done by these organizations also shows that Oxitec is trying to influence regulatory processes for GM insects, that they (3):

·         Don’t want to be liable for any complications

·         Try to avoid any regulation of GM agricultural pests on crops appearing in the food chain

·         Excludes important issues from risk assessments, like the impact on human health

·         Release of large amounts of GM insects prior to regulations

·         Undermining the requirement to obtain informed consent for experiments involving insect species which transmit disease

The list of concerns go on and on. This is something that you don’t hear in corporate media, despite the importance of dialogue, it seems developments within this field are sneaking by very quietly. Should we not discuss this? Should there not be a proper risk assessment done? Concerning ourselves with our food, health and our environment is something we need to take very seriously. Developments that should attract a great deal of concern are happening without anybody knowing about them. These are some of the most important issues that our world faces today and some of the most important issues that will contribute in shaping the near future of our planet and the path we choose to take.

Sources:

 

http://www.collective-evolution.com/2013/09/10/thousands-of-genetically-modified-insects-are-set-for-release/

http://www.scientificamerican.com/article.cfm?id=genetically-engineered-mosquitoes

http://www.nature.com/nbt/journal/v29/n11/full/nbt.2019.html

(3)http://www.testbiotech.de/sites/default/files/Briefing%20genetically%20engineered%20Insects.pdf

(2)http://www.inasp.info/uploads/filer_public/2013/04/03/3_handout_1.pdf

(1)http://www.dailymail.co.uk/sciencetech/article-2410484/Scientists-launch-thousands-GM-insects-fields-alternative-chemicals.html

(4)http://farmwars.info/?p=9457