Dementia, despite its prevalence, remains largely a mystery to doctors and scientists, who have yet to find a foolproof way to prevent or treat the illness. We’ve all heard that foods like blueberries and those containing omega 3s can reduce your risk to a degree, but one of the more exciting developments in the fight against dementia in recent years is the ability of coenzyme Q10, or coQ10, to significantly lower your risk.
A study that was published in the Atherosclerosis journal highlighted this ability after looking at adults aged between 40 and 69. They compared those who developed dementia with control subjects who were the same age but did not develop the disease, measuring the serum CoQ10 levels of everyone involved.
They discovered that those individuals whose levels of CoQ10 were within the top 25 percent of all those measured enjoyed a remarkable 77 percent lower chance of developing dementia than those who fell into the lowest quarter of CoQ10 levels. In addition, those with the highest levels of CoQ10 also had healthier levels of cholesterol.
Why is CoQ10 so useful in this regard? According to experts, it lowers oxidative stress in the brain, along with amyloid plaque. It also helps to heal the mitochondrial impairment that stands in the way of energy production.
Could you use more CoQ10?
Your body naturally produces the antioxidant CoQ10, which is also known as ubiquinone. Its main job is helping your body convert the food you eat into the energy needed to power your brain and your body in general, but it also serves other purposes, such as preventing blood clots.
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As you age, your CoQ10 levels will decrease naturally, and they also drop very low if you have heart disease, dementia, Parkinson’s, HIV/AIDS, or cancer. Deficiencies can also be seen in those who take statins. Unfortunately, having low levels of CoQ10 has been linked to a host of illnesses like cancer progression and melanoma metastasis.
Because nearly every cell in your body depends on CoQ10, it’s important to ensure you are getting enough of it – especially if you are hoping to reduce your chances of developing dementia later in life, along with other brain diseases like Parkinson’s.
You can find CoQ10 in oily fish like salmon, sardines, mackerel and tuna, which also have the benefit of containing lots of healthy fats. It can also be found in soybeans, peanuts, spinach, cauliflower, and broccoli.
It’s difficult to get enough CoQ10 from your diet, so many people enlist the help of supplements to ensure their levels are adequate. In fact, CoQ10 supplements have proven useful in lowering cancer risk and helping to heal heart disease. The supplements can also help those suffering from high blood sugar and even diabetes.
Because it’s made naturally by your body, it is considered generally quite safe to take as a supplement, as long as you are getting a pure product from a trustworthy source. Studies haven’t found any serious side effects, although some people may experience mild effects like nausea, heartburn, headaches or insomnia. Some people might want to steer clear, however, such as those who are pregnant or taking blood thinners, chemotherapy medications, or beta blockers.
Although we are still only scratching the surface when it comes to understanding this puzzling disease, it’s encouraging to know that there are safe and natural ways you can reduce the chances you’ll develop dementia.
Following your doctor prescribed cholesterol-lowering regimen that may include eating healthy, exercising regularly, and taking cholesterol medication such as statins can help keep your cholesterol in check.
However, it’s a bit of a double-edged sword. While statins help to keep your cholesterol levels under control, they can also deplete your body of essential compounds and chemicals that keep the body running smoothly.
More importantly, if you have high cholesterol and are currently taking statin medication, you run the risk of significantly lowering your normal CoQ10 levels, something that could compromise your normal body functions.
According to the University of Maryland Medical Center (UMMC), there is no doubt that statins will “reduce the natural levels of CoQ10 in the body.” In fact, it has been shown that statins can lower CoQ10 levels by up to 40%. This could potentially complicate other health issues and leave you vulnerable to side effects from your prescribed statins.
There is some good news, however. The UMMC reports that “taking CoQ10 supplements might help increase levels in the body and reduce problems.” It further suggests that CoQ10 may support healthy cardiovascular function – something worth considering, especially if you have a history of heart disease in your family.
What is CoQ10?
The term may look like something off the molecular chart from your high school science class, but coenzyme Q10 is the only name we have to describe this essential antioxidant.
What does it actually do, though?
You could say that CoQ10 is a bright spark in the tinderbox, as it gets everything fired up. From vital organs to muscles, you’ll find CoQ10 in every cell (did you know that the highest concentrations can be found in your heart, liver, and kidneys?), balancing electrons, producing energy and fighting off free radicals. It’s the life of the party! In essence, it’s an energy-producing coenzyme that keeps your engine running on all cylinders.
The Power Plant of Every Living Cell
It’s hard to imagine our cells busy at work, rushing through our bloodstream to every organ and muscle in the body, repairing, building, and fighting off intruders. It’s a beehive of industry and this requires a lot of energy. This energy is produced by a complex series of biochemical reactions that results in the production of Adenosine triphosphate (ATP), which is the energy currency of the cell. CoQ10 is essential to this process due to its electron transfer characteristics and is in fact a vital factor for 95% of the overall energy production at the cellular level.
Thanks to CoQ10, this energy breathes life into your body and keeps it functioning optimally. However, when you’re taking statins, CoQ10 levels are significantly lowered.
What Happens When There’s a Shortage of CoQ10?
As you get older, CoQ10 levels naturally decline and researchers have identified CoQ10 deficiency as a contributing factor to many health conditions. Heart disease is probably the most common condition that can be affected by a CoQ10 deficiency, and this includes heart failure, angina, high blood pressure, high cholesterol, and cardiovascular disease. CoQ10 is often recommended by general practitioners and cardiologists alike as a dietary supplement to help assure adequate levels of this coenzyme, especially if you’ve been prescribed statins. It’s has also proven to be an effective after-care supplement for heart failure, heart surgery, and chemotherapy.
CoQ10 is found in a bunch of foods like meat, fish, and whole grains. In a healthy, balanced diet, it should be in adequate supply. However, certain diseases like diabetes, Parkinson’s, and heart disease, as well as drugs like statins can diminish your natural CoQ10 levels considerably. In these instances, the best way to return to normal levels is for you to supplement your diet with CoQ10.
Your organs require huge amounts of CoQ10 to carry out their daily functions. So you can understand how vital this antioxidant is to ensure their health. It’s also a critical component in regulating blood sugar levels and is often also recommended to diabetic patients. Because of how essential it is for energy production and its characteristics as a powerful antioxidant, CoQ10 supplementation is regularly recommended for people with cancer, muscular dystrophy, and periodontal disease.
Is CoQ10 Good for Muscle Pain Caused by Statins?
CoQ10 is in hot demand by the body, as its role is critical in maintaining the overall health of your body. Your organs rely on it, and so too do your muscles. In fact, they can’t function without it.
During any given day, your muscle fibers break down and rebuild in order to get stronger. It’s a bit like housekeeping. Old muscle cells are swept away, with the arrival of fresh cells that are brimming with life.
Deep inside these muscle fibers, you’ll find CoQ10 delivering fresh energy stores to cells in need, as well as warding off intruders. But when levels of CoQ10 are compromised by statins, proper muscle function can be impaired, and the whole process begins to collapse. The result is muscle pain and joint stiffness – one of the common side effects of statins. Muscle soreness can seriously affect your mobility, not to mention, your quality of life. It also increases your risk of falling, as it leaves you unsteady on your feet.
According to a study published in the American Journal of Cardiology, CoQ10 can help alleviate muscle pain and joint discomfort brought on by statin drugs:
“Results suggest that coenzyme Q10 supplementation may decrease muscle pain associated with statin treatment. Thus, coenzyme Q10 supplementation may offer an alternative to stopping treatment with these vital drugs” – American Journal of Cardiology
Not only is CoQ10 essential in maintaining heart and organ health, it is also instrumental in the proper functioning of your muscles. And one of the secrets to longevity and quality of life is strong muscles.
CoQ10 And Statins – It Makes Sense to Supplement with CoQ10
This vital coenzyme is so essential to the body that you’ll notice immediately if you’re in short supply. Because statins can rob your body of this vital component, it makes sense to supplement your diet with CoQ10. There’s also the added health benefit of its anti-aging, antioxidant properties that help to prevent free radicals from damaging your tissues.
Talk to your doctor to see if CoQ10 is right for you, especially if you’re currently taking statins. It’ll make all the difference to your quality of life.
Following your doctor prescribed cholesterol-lowering regimen that may include eating healthy, exercising regularly, and taking cholesterol medication such as statins can help keep your cholesterol in check.
However, it’s a bit of a double-edged sword. While statins help to keep your cholesterol levels under control, they can also deplete your body of essential compounds and chemicals that keep the body running smoothly.
More importantly, if you have high cholesterol and are currently taking statin medication, you run the risk of significantly lowering your normal CoQ10 levels, something that could compromise your normal body functions.
According to the University of Maryland Medical Center (UMMC), there is no doubt that statins will “reduce the natural levels of CoQ10 in the body.” In fact, it has been shown that statins can lower CoQ10 levels by up to 40%. This could potentially complicate other health issues and leave you vulnerable to side effects from your prescribed statins.
There is some good news, however. The UMMC reports that “taking CoQ10 supplements might help increase levels in the body and reduce problems.” It further suggests that CoQ10 may support healthy cardiovascular function – something worth considering, especially if you have a history of heart disease in your family.
What is CoQ10?
The term may look like something off the molecular chart from your high school science class, but coenzyme Q10 is the only name we have to describe this essential antioxidant.
What does it actually do, though?
You could say that CoQ10 is a bright spark in the tinderbox, as it gets everything fired up. From vital organs to muscles, you’ll find CoQ10 in every cell (did you know that the highest concentrations can be found in your heart, liver, and kidneys?), balancing electrons, producing energy and fighting off free radicals. It’s the life of the party! In essence, it’s an energy-producing coenzyme that keeps your engine running on all cylinders.
The Power Plant of Every Living Cell
It’s hard to imagine our cells busy at work, rushing through our bloodstream to every organ and muscle in the body, repairing, building, and fighting off intruders. It’s a beehive of industry and this requires a lot of energy. This energy is produced by a complex series of biochemical reactions that results in the production of Adenosine triphosphate (ATP), which is the energy currency of the cell. CoQ10 is essential to this process due to its electron transfer characteristics and is in fact a vital factor for 95% of the overall energy production at the cellular level.
Thanks to CoQ10, this energy breathes life into your body and keeps it functioning optimally. However, when you’re taking statins, CoQ10 levels are significantly lowered.
What Happens When There’s a Shortage of CoQ10?
As you get older, CoQ10 levels naturally decline and researchers have identified CoQ10 deficiency as a contributing factor to many health conditions. Heart disease is probably the most common condition that can be affected by a CoQ10 deficiency, and this includes heart failure, angina, high blood pressure, high cholesterol, and cardiovascular disease. CoQ10 is often recommended by general practitioners and cardiologists alike as a dietary supplement to help assure adequate levels of this coenzyme, especially if you’ve been prescribed statins. It’s has also proven to be an effective after-care supplement for heart failure, heart surgery, and chemotherapy.
CoQ10 is found in a bunch of foods like meat, fish, and whole grains. In a healthy, balanced diet, it should be in adequate supply. However, certain diseases like diabetes, Parkinson’s, and heart disease, as well as drugs like statins can diminish your natural CoQ10 levels considerably. In these instances, the best way to return to normal levels is for you to supplement your diet with CoQ10.
Your organs require huge amounts of CoQ10 to carry out their daily functions. So you can understand how vital this antioxidant is to ensure their health. It’s also a critical component in regulating blood sugar levels and is often also recommended to diabetic patients. Because of how essential it is for energy production and its characteristics as a powerful antioxidant, CoQ10 supplementation is regularly recommended for people with cancer, muscular dystrophy, and periodontal disease.
Is CoQ10 Good for Muscle Pain Caused by Statins?
CoQ10 is in hot demand by the body, as its role is critical in maintaining the overall health of your body. Your organs rely on it, and so too do your muscles. In fact, they can’t function without it.
During any given day, your muscle fibers break down and rebuild in order to get stronger. It’s a bit like housekeeping. Old muscle cells are swept away, with the arrival of fresh cells that are brimming with life.
Deep inside these muscle fibers, you’ll find CoQ10 delivering fresh energy stores to cells in need, as well as warding off intruders. But when levels of CoQ10 are compromised by statins, proper muscle function can be impaired, and the whole process begins to collapse. The result is muscle pain and joint stiffness – one of the common side effects of statins. Muscle soreness can seriously affect your mobility, not to mention, your quality of life. It also increases your risk of falling, as it leaves you unsteady on your feet.
According to a study published in the American Journal of Cardiology, CoQ10 can help alleviate muscle pain and joint discomfort brought on by statin drugs:
“Results suggest that coenzyme Q10 supplementation may decrease muscle pain associated with statin treatment. Thus, coenzyme Q10 supplementation may offer an alternative to stopping treatment with these vital drugs” – American Journal of Cardiology
Not only is CoQ10 essential in maintaining heart and organ health, it is also instrumental in the proper functioning of your muscles. And one of the secrets to longevity and quality of life is strong muscles.
CoQ10 And Statins – It Makes Sense to Supplement with CoQ10
This vital coenzyme is so essential to the body that you’ll notice immediately if you’re in short supply. Because statins can rob your body of this vital component, it makes sense to supplement your diet with CoQ10. There’s also the added health benefit of its anti-aging, antioxidant properties that help to prevent free radicals from damaging your tissues.
Talk to your doctor to see if CoQ10 is right for you, especially if you’re currently taking statins. It’ll make all the difference to your quality of life.
CoQ10 by itself is also known as ubiquinone. To benefit from the form of the nutrient needed to produce cellular energy and help you reduce the typical signs of aging, your body must convert the ubiquinone to ubiquinol.
Ubiquinol exists everywhere there is life… it’s ubiquitous!
The challenge you face as you age is this — your body levels of CoQ10 continue to diminish.
In addition, your capability to convert CoQ10 to ubiquinol also declines. It becomes more and more difficult for you to produce the ubiquinol you need due to:
If you take statin drugsCritical CoQ10 levels decline as you age. So I believe this is a must-have supplement!
Increased metabolic demand
Oxidative stress
Insufficient dietary CoQ10 intake
Deficiency of factors required for biosynthesis and ubiquinol conversion
Potential effects from illness and disease
Age-related changes in your genes
And any combination of these factors
Some reports say your CoQ10 level decline becomes apparent as early as your 20’s.
The good news is with the Mercola Advanced Nutrition supplement, you now can have the ubiquinol formula direct… the active form of the CoQ10 nutrient*.
Your added benefits from the ubiquinol formula can be significant as you…
Potentially absorb more CoQ10 — as shown in studies by enhanced blood plasma levels*
Become less dependent on your body to convert ubiquinone to ubiquinol… In the plasma of healthy humans, more than 90% of CoQ10 exists in the reduced form (ubiquinol).*
Absorb CoQ10 that’s already in the active state your body needs*
Receive the reduced (unoxidized) form of CoQ10 for added cellular energy*
Get a strong first stage defense against oxygen free radicals to help you reduce the typical signs of aging and optimize your health*
However, not everyone needs the ubiquinol formula. If you’re younger than 25, your body should absorb regular CoQ10 just fine.
In fact, research studies show that younger people don’t absorb ubiquinol as well as older folks. So if you’re young, sticking to a regular formula makes more sense.
That’s why I decided to offer both regular CoQ10 and ubiquinol-based CoQ10 in my line of Mercola Advanced Nutrition supplements.
Plus, I’m so convinced of the reduced aging and energy-boosting capabilities, I personally recommend Mercola Advanced Nutrition Ubiquinol to family and friends over 25.
And let me show you more on…
How to Help Turn Your Declining CoQ10 Levels into a Healthier YOU*
The Mercola Advanced Nutrition CoQ10 and ubiquinol supplements can help you in many different ways to complement your healthy diet and energize your life.
Help you produce more energy for your cells*
Act as a catalyst in your body’s various chemical reactions, leading to the production of energy.*
Ignite your body’s engine by jump-starting energy production in your cells.*
You’ll enjoy your new-found energy and stamina levels.*
Boost your heart health*
Help strengthen your overall cardiovascular system.*
Help maintain and balance the critical energy level needed in your body’s most vital muscle… your heart.*
Since you’re passionate about life, you need an optimally-functioning heart.*
Act as an antioxidant to help protect you from free radicals*
Provide your body with added defense against oxidation stress to your cells, tissues, and organs.*
Help recharge other antioxidant nutrients to their active states — and keep them working for you.*
You’ll feel good about yourself, knowing you’re taking steps to live a healthy life.*
Help you reduce the signs of normal aging*
Help you potentially feel more alert and responsive.*
By keeping blood levels high in CoQ10, help you maintain your vitality.*
You’re determined to feel young and full of life… don’t let aging get the best of you.*
Help you maintain blood pressure levels within the normal range*
Promote healthy blood circulation in your body and a more efficient heart.*
Research indicates maintaining proper levels of CoQ10 can help you maintain normal blood pressure levels.*
Just by knowing you’re taking more steps to take control of your health, you could feel more relaxed and less stressed out.*
Provide a boost to your immune system*
Help promote your healthy immune system.*
Help support your immune system by providing a defense against free radicals.*
You’ll feel great about yourself knowing you’re taking action to potentially boost your immune system.*
Support your nervous system*
Help promote an active mind.*
Your brain is one of the most active organs in your body and requires uninterrupted energy.*
Nothing beats having an active mind to help you deal with all of life’s challenges — and to help you make healthy decisions for your family.*
By now, you should see the power of CoQ10 and ubiquinol, and understand why I believe they provide you with extraordinary benefits to complement your healthy diet.*
There’s another very strong reason to take CoQ10 supplements…
Why You Should Replenish Your CoQ10 Levels When Taking Statin Drugs
If you or anyone you know is taking a statin drug, I truly believe it is absolutely essential to start taking a CoQ10 or ubiquinol supplement immediately to replenish your CoQ10 levels.
If you take statin drugs to lower cholesterol, I believe it’s essential for you to replenish your CoQ10 levels!
Why?
Statin drugs work to lower your cholesterol in the same pathway your body uses to produce CoQ10.
Now you might ask: “Why would you take a statin drug in the first place?”
Good question.
Normally, I believe well over 99% of people placed on statin drugs do not need them (although you should always consult a physician before stopping any medication).
I believe people should be able to easily optimize their cholesterol levels with simple lifestyle changes.
However, I have been practicing medicine for far too long to know the journey to good health can be long and complex for many. Some people simply require more time to make the transitions in weaning off these dangerous drugs.
So if you or someone you care about is taking a statin, I recommend (based on your age) you start using a high quality CoQ10 or ubiquinol supplement right away.
But not just any CoQ10 supplements.
To be in line with my mission to provide you only the best, you should…
Never, Ever Settle for 2nd Best
As with any supplement I recommend on my site, I established stringent criteria to find you the ultimate CoQ10 and ubiquinol formulas.
This thorough process ensures you can take full advantage of all the benefits the supplements have to offer.
My strict criteria for selecting top-notch CoQ10 and ubiquinol supplements for you?
They must:
Deliver high-absorption formulas regardless of your age*
NOT contain any synthetic ingredients
Come from a highly reputable company with some of the strictest quality control and safety standard practices in place
So far, I believe the Mercola Advanced Nutrition CoQ10 supplements deliver high-absorption formulas*. That’s why I offer both regular CoQ10 for those under 25 years old, and ubiquinol if you’re over 25.
I’ll cover more on my selection criteria later on. But first, here are even more advantages you’ll get from using these supplements and…
Why These Formulas Stand Above the Rest
As you’ve already seen, using a high-quality CoQ10 or ubiquinol supplement provides you great benefits:*
And in my opinion, statin drug users should begin taking the supplement immediately to help replenish their CoQ10 levels.
With my Mercola Advanced Nutrition CoQ10 and ubiquinol supplements, there are even more possible advantages for you in the way they…
Support healthy gums*
Boost your body’s immune system*
Help maintain normal blood sugar levels*
Support muscle recovery from intensive workouts*
Promote normalization of your weight*
It gets even better, as my Mercola Advanced Nutrition CoQ10 supplements are…
Does Not Contain Any Synthetics
Very exclusive processes drive the creation of these supplements. Innovative manufacturing using biological fermentation delivers pure CoQ10 and ubiquinol.
This is right in line with one of my most stringent selection criteria.
These processes ensure you get stabilized, high-absorption formulas.
And when it comes to ubiquinol, one of the biggest challenges faced by any manufacturer is how easily ubiquinol oxidizes in the air. This adds to the instability of the nutrient.
To overcome this issue, the manufacturer of the Mercola Advanced Nutrition Ubiquinol supplement established technology that enables the production of ubiquinol in stable bulk quantities.
This results in a formula that achieves higher elevations of circulating CoQ10 in your bloodstream.*
Plus, there’s more terrific news about ubiquinol…
Licaps® — New and Exciting Delivery Technology
Ubiquinol is now delivered in a “Licaps®” capsule instead of a softgel or caplique. Licaps use innovative “Fusion Technology” to seal a 2-piece capsule without the use of banding.
This extraordinary liquid capsule technology can provide many beneficial advantages over others because it…
Reduces oxidation potential by flushing the liquid formulation with nitrogen during the capsule-filling process – Creates a ‘freshness bubble’
Ensures 2-piece capsules are hermetically sealed to significantly reduce the potential for leakage – Yields a precisely tight, one-piece capsule
Enhances shelf-life through exemplary filling and sealing processes
The bottom line with Licaps… the possibility of leakage is virtually reduced to zero while absorption is enhanced.
Over a Year Spent Selecting Just the Right Manufacturer
My team and I spent over 18 months doing our due diligence with the Licaps’ manufacturer Capsugel, before agreeing to any sort of partnership.
And I wasn’t just satisfied to read and hear about Capsugel’s incredible innovation and quality processes, I personally traveled there myself to witness them first-hand.
Just as you look at credentials when you’re hiring a contractor or an employee, it’s wise to highly scrutinize the credentials of the company making your supplements… and that’s exactly what I did with this manufacturer.
In choosing Capsugel to produce my ubiquinol formula, careful attention was paid to their quality processes… so you would have the very best ubiquinol product I could find to enhance your health.
Here is just some of the history behind this innovative company…
Developed the concept of sealing a capsule without ‘banding’ in response to consumer safety concerns in the late 1980s (called ‘Licaps’)
Spent more than 15 years developing the Licaps capsule design and processes
Successfully received cGMP certification for its facility in France in 2003
Has been a world-leader in capsule manufacturing for more than a century – Has 10 manufacturing sites running 24/7 in the Americas, Asia, and Europe
Produces over 50% of all two-piece capsules out there today – more than 180 billion capsules on an annual basis
You can rest assured knowing that my team and I have made a well thought-out and investigated choice in providing you a high-quality product.
Have Trouble Swallowing Capsules or Pills?
According to a Harris interactive survey…
At one time or another, an astonishing 40% of American adults experience pill-swallowing difficulties…
Almost twice as many women as men (51% vs. 27%) have difficulty swallowing pills…
Shockingly… only 14% inform their doctors of this difficulty…
And surprisingly, the ‘40% statistic’ also applies to people who don’t usually have difficulty swallowing food.
Perhaps you’ve had problems swallowing capsules or pills at one time or another… or, maybe it’s become a constant challenge in your life.
To help with this issue and for folks who simply don’t want to take capsules or pills, I’ve come up with the perfect alternative for my ubiquinol supplement in the—Mercola Advanced Nutrition Ubiquinol Liquid Pump.
The key to the Ubiquinol Liquid Pump supplement is the airless pump technology my team uncovered while searching for a healthful tea to go on the site as well.
The airless pump technology helps preserve the ubiquinol from oxygen intrusion – One of the biggest factors that may cause ubiquinol to go oxidize is the air itself.
To use, simply pump it into a drink or onto your favorite salad… no more capsules and pills if you want to avoid them. And it tastes similar to olive oil.
Why Would You Settle for Inferior Quality?
Just as my team and I performed thorough ‘due diligence’ with the ubiquinol supplements, the same holds true for my regular CoQ10 formula… Advanced Nutrition CoQ10
It was a must that the developer and manufacturer of regular CoQ10 could demonstrate proven quality practices.
There are literally hundreds, if not thousands, of CoQ10 supplements on the market today… but there are only a few great ones out there.
When I first started my investigation, the low quality demonstrated by so many companies absolutely shocked me.
But after many long months researching CoQ10 manufacturers, I believe the manufacturer of choice for my regular formula is one of the top CoQ10 supplement producers in the U.S. today.
Here’s why I firmly believe the manufacturer of Mercola Advanced Nutrition CoQ10 clearly stands apart in it’s quality standard practices…
Follows strict Pharmaceutical GMP standards in its manufacturing processes
Awarded and filed applications on at least 24 US and international patents — including 10 for its manufacturing processes
Announced self-affirmed GRAS (Generally Recognized as Safe) status–performed all necessary research and provided supporting materials regarding production methods, quality assurance, and safety (no objection letter was issued)
You should clearly see why I chose this manufacturer to provide you with the highest quality Mercola Advanced Nutrition CoQ10 supplement.
Don’t ever settle for a supplement unless it is solidly backed by a manufacturer practicing the highest quality standards.
To you, quality means a consistent top-of-the-line product every time you use it.
How High-Quality Means Exceptional Value You Can Rely On
The scientific community continues to conduct many research studies using CoQ10 in both ubiquinone and ubiquinol forms.
To date, the safety and reliability reports on these supplements remain solid.
This should always be important to you when considering taking any supplement… I know it is for me.
From the American Cancer Society: “Few serious reactions to CoQ10 have been reported.”
From the University of Maryland Medical Center: “Coenzyme Q10 appears to be generally safe with no significant side effects…”
From the National Center for Complementary and Alternative Medicine (NCCAM) at the National Institutes of Health (NIH): “No serious side effects have been reported from the use of coenzyme Q10.”
I bet you agree — this is excellent feedback on CoQ10 safety.
With the superior high-quality practices in place for the entire family of Mercola Advanced Nutrition CoQ10 supplements, I feel these are true winners.
And here are…
5 Clear-Cut Reasons For You to Act Now
Now you should understand why I’m so excited to bring you these extraordinary CoQ10 supplements. They passed all of my stringent selection criteria for supplements to be offered on my site.
Let me quickly summarize all this for you with 5 clear-cut reasons why you should take action and order these supplements without delay.
The Mercola Advanced Nutrition CoQ10 supplements can:
Boost your energy and stamina levels*
Support the health of your cardiovascular system*
Help you feel younger and reduce the normal signs of aging*
Enhance the support of your immune and nervous systems*
Replenish your CoQ10 levels if you’re taking a statin drug*
Before you jump in and place your order, there’s some real important information I want you to have in…
How Two Different Types of Antioxidants Work Together
to Neutralize Free Radicals*
Antioxidants are generally classified into two broad categories…water soluble (hydrophilic) and lipid soluble (hydrophobic).
Your body needs both types of antioxidants because each one targets different types of cells and tissues for free radical scavenging…
Water soluble antioxidants – These are present in aqueous fluids, such as blood and intracellular and extracellular fluids. They react with oxidants in the cell cytosol (fluid portion of cytoplasm) and the blood plasma. Examples of water soluble antioxidants include… vitamin C, glutathione, and catechins.
Lipid soluble antioxidants – These are localized to cellular membranes and lipoproteins. They protect cell membranes from lipid peroxidation.* Examples of lipid-soluble antioxidants include… vitamins E, A, and beta carotene.
The bottom line… to fight and help neutralize pesky free radicals, you need both types of antioxidants from as many sources as possible.* When taken together, the efficacy of water- and lipid-soluble antioxidants is enhanced even more.
The antioxidants found in Purple Defense (anthocyanins, polyphenols, resveratrol) are water-soluble antioxidants. Both Astaxanthin and Ubiquinol contain lipid-soluble antioxidants.
Each type of antioxidant has its own special function in helping repair and protect your cells from free radical damage.* Water-soluble Purple Defense helps repair the interior of cells… Lipid-soluble Astaxanthin helps repair fat/cell membranes… Lipid-soluble Ubiquinol acts as an antioxidant recycler for vitamins C and E.*
OBJECTIVE: To evaluate the efficacy of coenzyme Q10 (CoQ10) supplementation on statin-induced myopathy. PARTICIPANTS AND
METHODS: We searched the MEDLINE, Cochrane Library, Scopus, and EMBASE databases (November 1, 1987, to May 1, 2014) to identify randomized controlled trials investigating the impact of CoQ10 on muscle pain and plasma creatine kinase (CK) activity as 2 measures of statin-induced myalgia. Two independent reviewers extracted data on study characteristics, methods, and outcomes.
RESULTS: We included 6 studies with 302 patients receiving statin therapy: 5 studies with 226 participants evaluated the effect of CoQ10 supplementation on plasma CK activity, and 5 studies (4 used in the CK analysis and 1 other study) with 253 participants were included to assess the effect of CoQ10 supplementation on muscle pain. Compared with the control group, plasma CK activity was increased after CoQ10 supplementation, but this change was not significant (mean difference, 11.69 U/L [to convert to mukat/L, multiply by 0.0167]; 95% CI, -14.25 to 37.63 U/L; P=.38). Likewise, CoQ10 supplementation had no significant effect on muscle pain despite a trend toward a decrease (standardized mean difference, -0.53; 95% CI, -1.33 to 0.28; P=.20). No dose-effect association between changes in plasma CK activity (slope, -0.001; 95% CI, -0.004 to 0.001; P=.33) or in the indices of muscle pain (slope, 0.002; 95% CI, -0.005 to 0.010; P=.67) and administered doses of CoQ10 were observed.
CONCLUSION: The results of this meta-analysis of available randomized controlled trials do not suggest any significant benefit of CoQ10 supplementation in improving statin-induced myopathy. Larger, well-designed trials are necessary to confirm the findings from this meta-analysis.
True health begins at the cellular level and our body contains roughly 75 trillion cells. The mitochondria is the key organelle within the cell that produces the majority of the energy. Coenzyme Q10 is a vital enzyme anti-oxidant within the mitochondria that is commonly deficient in many individuals.
Coenzyme Q10 is an anti-oxidant enzyme within the mitochondria. This anti-oxidant regenerates other antioxidants such as vitamin E. Its major role is helping the mitochondria harvest energy producing adenosine triphosphate (ATP) from the foods we eat. More than 75% of our energy is produced through the use of CoQ10 (1).
There are two major factors that lead to deficiency ofCoQ10 in human beings:
1. Reduced biosynthesis
2. Increased Utilization by the body.
Biosynthesis is the major source of CoQ10. Biosynthesis requires at least 12 genes and mutations in many of them cause CoQ10 deficiency. A few other genetic defects such as mutations of mitochondrial DNA can also influence. Some chronic diseases such as cancer, heart disease, etc., may also reduce the biosynthesis and increase the demand for CoQ10 in the body (2).
Poor lifestyle habits such as a diet rich in sugar and processed foods, smoking, poor sleeping habits, sedentary habits or overtraining all increase coQ10 utilization and thus deplete coQ10 levels. Chronic infections, environmental toxicity and high amounts of emotional stress all deplete coQ10 levels as well.
Aging and statin medication usage on CoQ10 levels:
CoQ10 is found in every cell of the body but is present in higher concentrations in organs that have higher energy requirements such as the kidneys, liver and heart. As we age, we lose our supply of CoQ10, particularly in the heart. By the time we are 80 years old our CoQ10 production is said to be about half of a 20 year olds. CoQ10 plays a huge role in energy supply in the heart and the vascular walls (3).
The most popularly prescribed cholesterol lowering medications, statins, have been shown to lower CoQ10 production by up to 40% (4). Unfortunately, many physicians remain unaware of this and they continue to prescribe statin cholesterol lowering medications without supplementing with CoQ10.
Low CoQ10 and chronic disease:
Cancer patients have been found to have low CoQ10 levels. This limits their ability to prevent against oxidative stress targeted at their DNA which leads to altered cellular function and abnormal cell development. CoQ10 supplementation has also been shown to be effective at slowing cancer growth and preventing its development (5, 6, 7).
CoQ10 has also been shown to improve brain health and reduce the severity and frequency of migraine headaches. Additionally, low CoQ10 is linked to degenerative neurological diseases such as Alzheimer’s, dementia and Parkinson’s. Supplemental coQ10 has been shown to strengthen the neuronal cell mitochondria and be a potent defense against neurological degeneration (8, 9).
Major studies have demonstrated that CoQ10 reduced oxidation and DNA double-strand breaks. This means that CoQ10 powerfully reduces stress on our DNA which is a key factor for anti-aging. It protects against damage to the arterial lining and keeps blood vessels strong and supple (10).
Best food sources of CoQ10:
The best food sources of CoQ10 are organ meats such as liver, heart and kidney. Wild-caught fish, grass-fed beef, wild game such as bison and venison and pastured poultry are all fantastic sources. Plant based sources include nuts, seeds and cruciferous veggies but in far smaller quantities than that found in animal foods.
The typical American diet provides about 10mg of CoQ10 daily. For a young individual with a strong and healthy digestive system this could be enough to supply their needs. As we age, our digestive system often gets compromised and we become very deficient in this key nutrient. This is when supplementation is necessary.
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