News and commentary from the world of neurology and neuroscience

Researchers studied over 700 first-person descriptions of brain fogopens in a new tab or window on social media to better understand its phenomenology. (Journal of Neurology, Neurosurgery, and Psychiatry)

A combination of guanfacine and the supplement N-acetylcysteineopens in a new tab or window appeared to help eight people with long COVID brain fog symptoms. (Neuroimmunology Reports)

Amyloid PET changes were similar between people with autosomal dominant Alzheimer’s disease and Down syndrome.opens in a new tab or window (Lancet Neurology)

The most common neurologic complaints seen in emergency departmentsopens in a new tab or window included headache, vertigo or dizziness, and general weakness, with a serious condition suspected in 10.1% of patients. (JAMA Neurology)

Anti-dementia drugs, including acetylcholinesterase inhibitors and memantine, were tied to shorter hospital stays and decreased mortality risk in people who had dementia with Lewy bodiesopens in a new tab or window. (PLoS Medicine)

Soluble phosphorylated tau (p-tau) biomarkers in cerebrospinal fluidopens in a new tab or window were more closely associated with cerebral amyloid-beta than with tau tangles, data from two observational cohorts showed. (JAMA Neurology)

Policy makers and funders need to support more inclusive research opens in a new tab or windowif the burden of dementia is to be tackled effectively, the editors of Lancet Neurology argued.

Starting disease-modifying treatment earlier was associated with better patient-reported physical symptomsopens in a new tab or window in multiple sclerosis, but not overall quality of life. (Journal of Neurology, Neurosurgery, and Psychiatry)

Satralizumab (Enspryng) reduced the risk of relapse in patients with aquaporin-4-immunoglobulin G-seropositive (AQP4-IgG+) neuromyelitis optica spectrum disorderopens in a new tab or window beyond the first 96 weeks of treatment, open-label extension data showed. (Neurology: Neuroimmunology & Neuroinflammation)