Systems biology research study reveals benefits of vacation, meditation


Scientists used a rigorous study design to assess the biological impact of meditation compared to vacation. The researchers found that a resort vacation provides a strong and immediate impact on molecular networks associated with stress and immune pathways, in addition to short-term improvements in well-being, as measured by feelings of vitality and distress. A meditation retreat, for those who already used meditation regularly, was associated with molecular networks characterized by antiviral activity. The molecular signature of long-term meditators was distinct from the non-meditating vacationers.

A resort vacation provides a strong and immediate impact on molecular networks associated with stress and immune pathways, in addition to short-term improvements in well-being, as measured by feelings of vitality and distress, say researchers.

Scientists from the Icahn School of Medicine at Mount Sinai, the University of California, San Francisco, and Harvard Medical School used a rigorous study design to assess the biological impact of meditation compared to vacation. They examined the effect of meditation on gene expression patterns in both novice and regular meditators. The researchers found that a resort vacation provides a strong and immediate impact on molecular networks associated with stress and immune pathways, in addition to short- term improvements in well-being, as measured by feelings of vitality and distress. A meditation retreat, for those who already used meditation regularly, was associated with molecular networks characterized by antiviral activity. The molecular signature of long-term meditators was distinct from the non-meditating vacationers. The study was published in Springer Nature’s journal Translational Psychiatry.

The study involved 94 healthy women, aged 30-60. Sixty-four women were recruited who were not regular meditators. Participants stayed at the same resort in California for six days, and randomized so that half were simply on vacation while the other half joined a meditation training program run by the Chopra Center for Well Being. The meditation program included training in mantra meditation, yoga, and self reflection exercises. It was designed by Deepak Chopra, MD, who did not participate in data collection or analysis.

For greater insight into the long-term effects of what scientists dubbed the “meditation effect” compared to the “vacation effect,” the team also studied a group of 30 experienced meditators who were already enrolled in the retreat that week. Researchers collected blood samples, and surveys, from all participants immediately before and after their stay, as well as surveys one month and ten months later.

“In the spirit of other research efforts we have pioneered with other groups, this work underscores the importance of studies focused on healthy people,” said Eric Schadt, PhD, senior author on the paper and the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai, and Founding Director of the Icahn Institute for Genomics and Multiscale Biology. “By combining an interrogation of gene networks with advanced data analysis and statistics, we have generated clinically meaningful information about stress and aging that is relevant to the broader population.”

The research team examined the changes in 20,000 genes to determine which types of genes were changing before and after the resort experience. Scientists performed an integrative transcriptomic analysis, comparing gene expression networks across all three groups of participants and finding unique molecular profiles and pathway enrichment patterns. Study results show that all groups — novice meditators, experienced meditators, and vacationers — had significant changes in molecular network patterns after the week at the resort, with a clear signature distinguishing baseline from post-vacation biology. The most notable changes in gene activity were related to stress response and immune function.

Researchers assessed self-reported measures of well being. While all groups showed improvements up to one month later, the novice meditators had fewer symptoms of depression and less stress much longer than the non-meditating vacationers. The psychological effects appear to be enduring and it is unknown how much of this longer lasting benefit may be due to continued practice or lasting changes in how people view events in their lives.

“It’s intuitive that taking a vacation reduces biological processes related to stress, but it was still impressive to see the large changes in gene expression from being away from the busy pace of life, in a relaxing environment, in such a short period of time. These findings will have to be replicated to see if the changes are reliably invoked under the same circumstances, in future studies, and compared to an at-home control group,” said Elissa S. Epel, PhD, Professor of Psychiatry at University of California, San Francisco and first author of the study.

“Based on our results, the benefit we experience from meditation isn’t strictly psychological; there is a clear and quantifiable change in how our bodies function,” said Rudolph Tanzi, PhD, the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard University, and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital. “Meditation is one of the ways to engage in restorative activities that may provide relief for our immune systems, easing the day-to-day stress of a body constantly trying to protect itself. The prediction is that this would then lead to healthier aging.”

4 Ways to Be Happy All the Time


ou only have one life and it is important that you make the most out of the time you have. This is done by making your happiness a priority. There are many things in life that can cause you to be stressed out and overwhelmed, but there are easy ways to bring back your happiness overnight. Here are the key takeaways from this infographic to make sure you stay happy and healthy.

1) Be Social

One of the biggest ways to make sure that you are happy is making an effort to be social. Staying in contact with friends can be a great way to make sure that you are fulfilled and feel like yourself. When you do not have time to stay connected to the people that matter most to you, this is when unhappiness can be the strongest. This means that if you make an effort to stay social, you should be able to keep your smile each day.

2) Be Adventurous

If you are looking to add something new to your life, you need to be willing to try something different. Happiness is often tied to be open to new experiences. This means that you need to be willing to get away from you normal routine and switch things up from time to time. It is the mundane tasks in life that can get you down in the dumps.

This means that you need to try new things and add a little adventure into your day in fun ways.

3) Positivity

Having a positive outlook on life and surrounding yourself with only positive people is one of the best ways to make sure that you are happy and fulfilled. Negativity is something that can seep into every part of your life and really weigh you down over time. This means that you need to stay away from negative people whenever possible. You need to be willing to always look for the bright side of a situation and stay away from those people that always see the glass as half empty. As long as you are healthy, you have no reason not to be happy.

4) Fun

You also need to add a little fun to your life if you want to be happy. All work and no play is no way to live. You need to have things in your day that you enjoy to keep you motivated and looking forward. Making time for a little fun is a great way to increase your happiness.

Watch the video. URL:https://youtu.be/5JhRK9zs8Es

Latest ocean warming review reveals extent of impacts on nature and humans.


Ocean warming is affecting humans in direct ways and the impacts are already being felt, including effects on fish stocks and crop yields, more extreme weather events and increased risk from water-borne diseases, according to what has been called the most comprehensive review available on the issue.

Aerial view of Arctic Ocean.

Ocean warming is affecting humans in direct ways and the impacts are already being felt, including effects on fish stocks and crop yields, more extreme weather events and increased risk from water-borne diseases, according to what has been called the most comprehensive review available on the issue, launched today by the International Union for Conservation of Nature (IUCN) at the IUCN World Conservation Congress in Hawai’i.

The report, Explaining ocean warming: Causes, scale, effects and consequences, reviews the effects of ocean warming on species, ecosystems and on the benefits oceans provide to humans. Compiled by 80 scientists from 12 countries, it highlights detectable scientific evidence of impacts on marine life, from microorganisms to mammals, which are likely to increase significantly even under a low emissions scenario.

“Ocean warming is one of this generation’s greatest hidden challenges — and one for which we are completely unprepared,” says IUCN Director General Inger Andersen. “The only way to preserve the rich diversity of marine life, and to safeguard the protection and resources the ocean provides us with, is to cut greenhouse gas emissions rapidly and substantially.”

Ocean warming is already affecting ecosystems from polar to tropical regions, driving entire groups of species such as plankton, jellyfish, turtles and seabirds up to 10 degrees of latitude towards the poles, causing the loss of breeding grounds for turtles and seabirds, and affecting the breeding success of marine mammals, according to the report.

By damaging fish habitats and causing fish species to move to cooler waters, warming oceans are affecting fish stocks in some areas and are expected to lead to reduced catches in tropical regions, the report states.

In East Africa and the Western Indian Ocean, for example, ocean warming has reduced the abundance of some fish species by killing parts of the coral reefs they depend on, adding to losses caused by overfishing and destructive fishing techniques. In South-East Asia, harvests from marine fisheries are expected to fall by between 10% and 30% by 2050 relative to 1970-2000, as the distributions of fish species shift, under a high ‘business as usual’ greenhouse gas emission scenario, the report states.

“Most of the heat from human-induced warming since the 1970s — a staggering 93% — has been absorbed by the ocean, which acts as a buffer against climate change, but this comes at a price. We were astounded by the scale and extent of ocean warming effects on entire ecosystems made clear by this report,” says Dan Laffoley, Marine Vice Chair of the World Commission on Protected Areas at IUCN, and one of the lead authors.

The report also highlights evidence that ocean warming is causing increased disease in plant and animal populations, and impacting human health as pathogens spread more easily in warmer waters, including cholera-bearing bacteria and harmful algal blooms that cause neurological diseases like ciguatera.

Warming oceans are also affecting the weather, with a range of knock-on effects on humans. The number of severe hurricanes has increased at a rate of around 25-30% per degree of global warming, the report states.

Ocean warming has led to increased rainfall in mid-latitudes and monsoon areas, and less rain in various sub-tropical regions. These changes will have impacts on crop yields in important food-producing regions such as North America and India, according to the report.

The protection against climate change offered to us by oceans and their ecosystems — such as absorbing large amounts of CO2 and sheltering us from storms and erosion — is also likely to reduce as the ocean warms, according to the report.

The report’s recommendations include recognising the severity of ocean warming impacts on ocean ecosystems and the benefits they provide to humans, expanding marine protected areas, introducing legal protection for the high seas, better evaluating the social and economic risks associated with warming oceans and continuing to fill gaps in scientific knowledge, as well as cutting greenhouse gas emissions rapidly and substantially.

Ocean conservation is one of the major themes addressed by the ongoing IUCN Congress, where IUCN Members will vote on motions related to protecting the high seas and protected areas in Antarctica among many others.