Plant Based Gel Can Seal Bleeding Wounds Instantaneously


blood-clotting-gel-lives.si

A New York based startup has developed a gel capable of sealing even the most severe bleeding wounds in mere seconds. The plant-based polymer is on the course to save human lives after already being tested in veterinarian use on animals.

Time has been of the essence in trying to save patients suffering from an open flesh wound, because if the bleeding isn’t stopped in time, the patient will die from bleeding out. And while there are various similar gels on the market, they can stop the bleeding in up to 10 minutes, while VetiGel, according the inventors, can get the job done in maximum 20 seconds.

Brooklyn based startup Suneris’s gel works on both skin and organ tissues by binding with components in blood and tissue . The plant cell wall polymers in the gel, when applied to the wound, duplicate the structure of the tissue.

By reassembling onto a wound site, VETIGEL mimics the body’s extracellular matrix and accelerates the production of fibrin, which enables the body to clot rapidly,” Suneris explains on its website.

So basically when the gel is applied part of it transforms on to the internal surface of a bleeding organ, another to broken blood vessel, and the outer part mimics the skin, eventually making the bleeding stop. The gel uses natural polymers to coordinate with the body’s natural cell clotting and accelerate hemostasis. It is applied directly to the source of bleeding and does not require manual pressure during treatment.

watch the video on youtube.URL:http://www.youtube.com/watch?feature=player_embedded&v=dJLxRcU9No4

Scientists convert human skin cells into sensory neurons


A team led by scientists from The Scripps Research Institute (TSRI) has found a simple method to convert human skin cells into the specialized neurons that detect pain, itch, touch and other bodily sensations. These neurons are also affected by spinal cord injury and involved in Friedreich’s ataxia, a devastating and currently incurable neurodegenerative disease that largely strikes children.

The discovery allows this broad class of human neurons and their sensory mechanisms to be studied relatively easily in the laboratory. The “induced sensory neurons” generated by this method should also be useful in the testing of potential new therapies for pain, itch and related conditions.

“Following on the work of TSRI Professor Ardem Patapoutian, who has identified many of the genes that endow these neurons with selective responses to temperature, pain and pressure, we have found a way to produce induced sensory neurons from humans where these genes can be expressed in their ‘normal’ cellular environment,” said Associate Professor Kristin K. Baldwin, an investigator in TSRI’s Dorris Neuroscience Center. “This method is rapid, robust and scalable. Therefore we hope that these induced sensory neurons will allow our group and others to identify new compounds that block pain and itch and to better understand and treat neurodegenerative disease and spinal cord injury.”

The report by Baldwin’s team appears as an advance online publication in Nature Neuroscience on November 24, 2014.

In Search of a Better Mode

The neurons that can be made with the new technique normally reside in clusters called dorsal root ganglia (DRG) along the outer spine. DRG sensory neurons extend their nerve fibers into the skin, muscle and joints all over the body, where they variously detect gentle touch, painful touch, heat, cold, wounds and inflammation, itch-inducing substances, chemical irritants, vibrations, the fullness of the bladder and colon, and even information about how the body and its limbs are positioned. Recently these neurons have also been linked to aging and to autoimmune disease.

Because of the difficulties involved in harvesting and culturing adult human neurons, most research on DRG neurons has been done in mice. But mice are of limited use in understanding the human version of this broad “somatosensory” system.

“Mouse models don’t represent the full diversity of the human response,” said Joel W. Blanchard, a PhD candidate in the Baldwin laboratory who was co-lead author of the study with Research Associate Kevin T. Eade.

A New Identity

For the new study, the team used a cell-reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG-type sensory neurons from ordinary skin cells called fibroblasts.

To start, the scientists examined previous experiments and identified several transcription factors—managerial proteins that switch on the activity of large sets of genes—that seemed crucial to the ability of immature neurons to develop into adult sensory neurons. They found that the combination of the transcription factors Brn3a plus Ngn1, or Brn3a plus Ngn2, reprogrammed a significant percentage of the embryonic mouse fibroblasts into what looked—and acted—like mature DRG-type sensory neurons.

“We added compounds including capsaicin, which activates pain receptors on DRG neurons, and menthol, which activates cold receptors, and saw subsets of our induced neurons light up with activity just as real DRG neurons would,” said Eade.

Remarkably, although mouse studies had indicated that different transcription factors were differently important for generating pain- and itch-sensing neurons versus pressure- and limb- position neurons, in the dish these factors produced equal numbers of each of the three main subtypes.

A Step Toward ‘Personalized Medicine’

Using the same recipes of transcription factors, the team was able to convert adult human fibroblasts, which are harder to reprogram, into DRG neurons. The conversion rate was lower, but the induced neurons seemed just as much like their natural counterparts as those produced from embryonic mouse fibroblasts.

“We can definitely scale up of the numbers of these induced as needed,” Blanchard said.

The feat means that scientists now can relatively easily study DRG derived from many different people to better understand the diversity of human sensory responses and sensory disorders and advance a “personalized medicine” approach. “We can start to understand how individuals respond uniquely to pain, cold, itch and so on,” said Blanchard.

Know Your Honey: Different types of honey and their health benefits


There are over 300 types of honey – and different honeys are good for different health issues…In general, we have the following:

1. Honey is antibacterial and antiseptic:  raw honey contains hydrogen peroxide, released when it comes into contact with moisture. Hydrogen peroxide is both antibacterial and fungicidal. Honey was originally used for therapeutic purposes, as it has antibacterial properties, but was replaced by antibiotics, such as penicillin and synthetic drugs in the 1940s and 1950s. Honey is also gyroscopic, which means that it naturally attracts moisture. Most bacteria breed in moist conditions and honey dries out wounds, preventing wounds becoming infected.
Know Your Honey  Different types of honey and their health benefits

2. Honey as a sweetener:   raw honey doesn’t cause the blood sugar to spike.  It allows a much healthier gradual increase in blood sugar levels. And we only a need a teaspoon to make a difference.

3. Dark honeys are high in antioxidants:   The darker the honey, the more antioxidant which eliminate free radicals.  HOney has a unique anti0oxidant:  pinocembrin, an antioxidant associated with improved brain functioning.

4. Honey can help you digest food better. Honey contains natural enzymes that assist the digestive process.

5. Honey is said to aid sleeping. The theory indicates that a spoonful of honey before sleep provides the body with enough glucose to ‘feed’ the brain during the night. This prevents or limits the early morning release of cortisol and adrenalin (stress hormones) which disturb sleep; stabilises blood sugar levels; contributes to the release of melatonin, the hormone required for recovery and rebuilding of body tissues during rest. (According to a recent study in Hershey, Penn, USA.)

6. Honey is good for your skin. Because honey attracts moisture, it helps to nourish the skin – that is why it is often used in skin care products. Also, honey’s antioxidants compounds help to fight free radicals, which can damage skin. Some people find honey is very effective for conditions such as sunburn, acne and eczema.

There are also different ways of processing honey…what you are looking for is:

• Not pasteurised (which degrades the enzymes, minerals and vitamins).
• Not ultra filtered – which removes the pollen and its benefits.
• Not a blend of different honeys from different countries (which almost all supermarket honey is, even when it is organic).
• The bees aren’t given antibiotics.
• The bees are fed honey not sugar (many beekeepers feed their bees sugar in the winter).

let’s take a look at what different honeys are recognized for:

The color and flavor of honeys differ depending on the nectar source (the blossoms) visited by the honey bees. In fact, there are more than 300 unique types of honey available in the United States, each originating from a different floral source. Honey color ranges from nearly colorless to dark brown, and its flavor varies from delectably mild to distinctively bold, depending on where the honey bees buzzed. As a general rule, light-colored honey is milder in taste and dark-colored honey is stronger….

Following is a look at some of the most common U.S. honey floral varieties. To learn more about available types of honey in your area, contact a local beekeeper, beekeeping association or honey packer. For help finding a honey packer or a specific floral source, visit the Honey Locator.

Know Your Honey  Different types of honey and their health benefits

ALFALFA

Alfalfa honey, produced extensively throughout Canada and the United States from the purple blossoms, is light in color with a pleasingly mild flavor and aroma.

Alfalfa is good for cardio issues…arteriosclerosis in addition to the anti-inflammatory, anti-oxidant and anti-bacterial properties.

AVOCADO

Avocado honey is gathered from California avocado blossoms. Avocado honey is dark in color, with a rich, buttery taste.

Avocado honey is rich with vitamins, minerals, anti-oxidants and offers many of the same medicinal properties as an aloe vera plant.

BLUEBERRY

Taken from the tiny white flowers of the blueberry bush, the nectar makes a honey which is typically light amber in color and with a full, well-rounded flavor. Blueberry honey is produced in New England and in Michigan.

According to the Brock University Blueberry and Buckwheat honeys have the highest antibacterial anti-oxidants

BUCKWHEAT

Buckwheat honey is dark and full-bodied. It is produced in Minnesota, New York, Ohio, Pennsylvania and Wisconsin as well as in eastern Canada. Buckwheat honey has been found to contain more antioxidant compounds than some lighter honeys.

While strong and dark, it has a high level of anti-oxidants.  It is considered one of the most valuable honeys native to Europe.  In comparison to other bright honeys, it contains more magnesium, iron, copper, zinc, phosphorus, nickel, bohrium, iodine and cobalt. If buckwheat honey is freshly extracted, it has: 51.6% fructose, 46.59% glucose and 0.27% sucrose.  There has been established that there is a lot of vitamin C (2.9 – 11.9mg %), B1, B2 and PP.  When it comes to the enzymes, content of the buckwheat honey is the richest among other Polish honeys. It has very high antibiotic qualities. According to research, its antibiotic characteristic is slightly better than Manuka honey’s 

It is recognized to have an impact on:

  • artherosclerosis
  • bacterial infection
  • diabetes (type 2)
  • liver (detox)
  • microcytic anemia (iron deficiency)

Clover honey has a pleasing, mild taste. Clovers contribute more to honey production in the United States than any other group of plants. Red clover, Alsike clover and the white and yellow sweet clovers are most important for honey production. Depending on the location and type of source clover, clover honey varies in color from water white to light amber to amber.

Again, there are many different types of clover and thus clover honey…but in general, clover honey is known for:

  • promoting wound healing and treating burns
  • regulating blood pressure
  • control liver issues
  • regulating cholesterol
  • providing anti-oxidants
  • mucus thinner and thus eliminates coughing

EUCALYPTUS HONEY

Eucalyptus honey comes from one of the larger plant genera, containing over 500 distinct species and many hybrids. As may be expected with a diverse group of plants, eucalyptus honey varies greatly in color and flavor but tends to be a stronger flavored honey with a slight medicinal scent. It is produced in California.

Eucalyptus honey is good for:  respiratory, anti-inflammatory, anti-spasmodic, decongestant, deodorant, antiseptic, antibacterial and stimulating health benefits – not bad for a teaspoon of honey…but you have to take it regularly.

FIREWEED HONEY

Fireweed honey is light in color and comes from a perennial herb that creates wonderful bee pasture in the Northern and Pacific states and Canada. Fireweed grows in the open woods, reaching a height of three to five feet and spikes attractive pinkish flowers.

There are over 50 types of Fireweed but they do apparently help to strengthen the immune system, respiratory system and improve the condition of the body.

MANUKA HONEY

Manuka honey, primarily produced in New Zealand, is used as a natural product both internally and topically on the skin. The bees gather nectar from the flowers of the Manuka bush, which is indigenous only to New Zealand. The honey making process is enriched by the pollution free environment of New Zealand.

Manuka honey has been found to be effective against Helicobacter pylori, which is pathogenic to the stomach and intestines and is involved in the formation of gastric ulcers and 12-duodenal ulcer, and gastric cancer. Helicobacter pylori taken from the ulcer with biopsies was sensitive to a 20% solution of Manuka honey. The growth of these bacteria was completely discontinued with 5-% solution of Manuka honey. 

NEEM

Neem honey is not in this list but I will put it in anyways.  Neem is a well recognized Ayurvedic plant utilized to treat:  allergies, diabetes, high blood pressure, dental & throat infections, skin conditions

ORANGE BLOSSOM HONEY

Orange blossom honey, often a combination of citrus sources, is usually light in color and mild in flavor with a fresh scent and light citrus taste. Orange blossom honey is produced in Florida, Southern California and parts of Texas.

Orange blossom honey contains:  quercetin, hesperitin, luteolin, kaempferol,  galangin, naringenin and isorhamnetin — antioxidants with anti-inflammatory,  anti-allergy, anti-cancer and immune supporting effects in the body

SAGE HONEY

Sage honey, primarily produced in California, is light in color, heavy bodied and has a mild but delightful flavor. It is extremely slow to granulate, making it a favorite among honey packers for blending with other honeys to slow down granulation.

Sage honey is a very pale honey and has less than 20% of the anti-oxidants of its darker cousins…but it still maintains all the other benefits of honey:  enzymes, antibacterial, antifungal, etc

TUPELO HONEY

Tupelo honey is a premium honey produced in northwest Florida. It is heavy bodied and is usually light golden amber with a greenish cast and has a mild, distinctive taste. Because of the high fructose content in Tupelo honey, it granulates very slowly.

As with most plants, there are a wide variety of Tupelos – the best for honey is said to be the pure white tupelo.  Along with antibacterial and anti-fungal benefits, tupelo honey to soothe coughs, sore throats, burns and as an anti-inflammatory,  but research about its health effects is inconclusive.  But it does contain: ” 25.95 percent dextrose, 43.27 percent fructose, 1.21 percent sucrose, 7.97  percent maltose and 1.1 percent higher sugars. It also contains thiamine,  riboflavin, ascorbic acid, nicotinic acid, sodium, potassium, magnesium,  manganese, iron, copper, calcium and phosphorous” 

WILDFLOWER HONEY

Wildflower honey is often used to describe honey from miscellaneous and undefined flower sources.

HONEY BLENDS

While different types of honey are available, most honey, especially honey supplied in bulk, is blended to create a unique and consistent taste and color.

10 Ways Vitamin E Can Bring The Glow Back To Your Skin And Hair


Vitamin E is a nutrient full of miraculous wonders that can rejuvenate our health and beauty. Taking Vitamin E capsules is considered good for health benefits. But very few are aware that this nutrient is amazing for skin and hair health when it is directly applied on the affected areas. You can either buy pure Vitamin E oil or get Vitamin E capsules (the purest form of the nutrient available in market, other than natural sources, of course), cut them, and use the serum inside for application. Here are 10 amazing hacks that will tell you how Vitamin E can bring that glow back to your skin and keep your hair shining and healthy.

1. Treats stubborn scars

Apply Vitamin E serum right out of the capsules to fight stubborn scars. Whether the scar is new or an old one, Vitamin E can work really well to ensure it fades away soon, leaving your skin much more beautiful. Gently apply the liquid from the capsules (or use Vitamin E oil) on the scar and massage it softly for a minute. In that way, Vitamin E will go deep into the skin layers and start working on the skin tissues of the affected areas. Make sure you apply it daily for better and faster results.

2. Deals with stubborn stretch marks

Most people will tell you those stubborn stretch marks are likely to stay for life. But you need not believe them. Just apply some Vitamin E liquid on those and the marks will fade soon. Take the liquid out of the Vitamin E capsules and mix it well with lemon juice. Now massage gently on the stretch marks for a while and leave it for about 30 minutes. Wash it off with water and you will immediately notice a difference. Apply the solution daily, for a month or so, for significant difference.

3. Treats eczema and psoriasis

Tough skin problems like eczema and psoriasis can also be cured by Vitamin E. Just apply Vitamin E oil on the affected skin every day and you will see improvement in skin conditions within a few weeks.

4. Get healthy nails

You can get those lustrous, beautiful, and long nails with the help of Vitamin E oil. It is a simple, easy, and effective solution for cracking and splitting nails. Even the dry cuticles that trouble you can be taken care of, with the help of Vitamin E. Just pour some Vitamin E serum from the capsules or put Vitamin E oil in a deep dish filled with water. Dip your fingers in it for 10 minutes and take them out. Do it for at least five times a week and see the magic for yourself. You can also apply the Vitamin E oil or serum directly on the nails.

5. Get soft and supple lips

Vitamin E is a great solution for chapped and dry lips. Applied directly on the lips, Vitamin E liquid (from the capsule) or Vitamin E oil works well as lip moisturizer and makes them smooth. Apply it regularly to make your lips supple and pink in color.

6. Great moisturizer for the skin

Mix a little Vitamin E liquid with your body lotion before applying it and it will keep your skin moisturized for a longer period of time. It will also even out any brown mark or dry skin patch. You can also pour some Vitamin E oil straight into your moisturizer bottle, shake it well, and apply the mixture daily.

7. Heals sunburns

Vitamin E can be a great healing agent for sunburns. Applying it on the skin helps the epidermis to absorb this nutrient directly and work on reversing the damage done by the harsh rays of the sun. Apply it twice a day to cure the burns faster.

8. Fights signs of aging

Vitamin E oil helps the skin make collagen that effectively slows down the process of skin aging. Incidentally, aging of the skin happens due to less collagen production in it. Applying Vitamin E directly on the skin stimulates skin cells and the production of collagen makes the fine lines disappear. Regular application will also prevent new wrinkles and lines appearing on your skin, thanks to the antioxidants found in the Vitamin E oil.

9. Battles premature graying of hair

Vitamin E also has the capability to slow down aging and rejuvenate your hair. Premature graying of hair is basically caused by oxidation of the tissues. Vitamin E application helps prevent the corrosion of tissues, which in turn stops the premature graying of your hair.

10. Smoothens split ends

Split ends steal the beauty away from your lovely locks. Usually, too much application of chemicals like hair colors or overstyling (blow drying, curling, straightening, etc.) cause severe damage to the hair and one of the biggest impacts will be split ends. But this can be treated easily with the help of Vitamin E and other oils. Mix equal parts of Vitamin E, olive oil, and coconut oil, and apply it on the split ends. Leave it on for an hour and shampoo it. Do this at least thrice a week and you will see the difference.

The Best Science Books of 2014.


The math of soul mates, the psychology of nothing, the physics of faith, and more illuminating insights on the universe and our place in it.

On the heels of the year’s most intelligent and imaginative children’s bookscome the most stimulating science books published this annum. (Step into the nonfictional time machine by revisiting the selections for 2013, 2012, and2011.)

1. THE ACCIDENTAL UNIVERSE

“If we ever reach the point where we think we thoroughly understand who we are and where we came from,” Carl Sagan wrote in his timeless meditation on science and religion, “we will have failed.” It’s a sentiment that dismisses in one fell Saganesque swoop both the blind dogmatism of religion and the vain certitude of science — a sentiment articulated by some of history’s greatest minds, from Einstein to Ada Lovelace to Isaac Asimov, all the way backGalileo. Yet centuries after Galileo and decades after Sagan, humanity remains profoundly uneasy about reconciling these conflicting frameworks for understanding the universe and our place in it.

That unanswerable question of where we came from is precisely what physicistAlan Lightman — one of the finest essayists writing today and the very first person to receive dual appointments in science and the humanities at MIT — explores from various angles in The Accidental Universe: The World You Thought You Knew (public library | IndieBound).

At the intersection of science and philosophy, the essays in the book explore the possible existence of multiple universes, multiple space-time continuums, more than three dimensions. Lightman writes:

Science does not reveal the meaning of our existence, but it does draw back some of the veils.

[…]

Theoretical physics is the deepest and purest branch of science. It is the outpost of science closest to philosophy, and religion.

In one of the most beautiful essays in the book, titled “The Spiritual Universe,”Lightman explores that intersection of perspectives in making sense of life:

I completely endorse the central doctrine of science. And I do not believe in the existence of a Being who lives beyond matter and energy, even if that Being refrains from entering the fray of the physical world. However, I certainly agree with [scientists who argue] that science is not the only avenue for arriving at knowledge, that there are interesting and vital questions beyond the reach of test tubes and equations. Obviously, vast territories of the arts concern inner experiences that cannot be analyzed by science. The humanities, such as history and philosophy, raise questions that do not have definite or unanimously accepted answers.

[…]

There are things we take on faith, without physical proof and even sometimes without any methodology for proof. We cannot clearly show why the ending of a particular novel haunts us. We cannot prove under what conditions we would sacrifice our own life in order to save the life of our child. We cannot prove whether it is right or wrong to steal in order to feed our family, or even agree on a definition of “right” and “wrong.” We cannot prove the meaning of our life, or whether life has any meaning at all. For these questions, we can gather evidence and debate, but in the end we cannot arrive at any system of analysis akin to the way in which a physicist decides how many seconds it will take a one-foot-long pendulum to make a complete swing. The previous questions are questions of aesthetics, morality, philosophy. These are questions for the arts and the humanities. These are also questions aligned with some of the intangible concerns of traditional religion.

[…]

Faith, in its broadest sense, is about far more than belief in the existence of God or the disregard of scientific evidence. Faith is the willingness to give ourselves over, at times, to things we do not fully understand. Faith is the belief in things larger than ourselves. Faith is the ability to honor stillness at some moments and at others to ride the passion and exuberance that is the artistic impulse, the flight of the imagination, the full engagement with this strange and shimmering world.

Dive deeper with Lightman on science and spirituality, our yearning for immortality in a universe of constant change, and how dark energy explains our accidental origins.

2. THE HUMAN AGE

In the most memorable scene from the cinematic adaptation of Carl Sagan’s novelContact, Jodi Foster’s character — modeled after real-life astronomer and alien hunter Jill Tarter — beholds the uncontainable wonder of the cosmos, which she has been tasked with conveying to humanity, and gasps: “They should’ve sent a poet!”

To tell humanity its own story is a task no less herculean, and at last we have a poet — Sagan’s favorite poet, no less — to marry science and wonder. Science storyteller and historianDiane Ackerman, of course, isn’t only a poet — though Sagan did send her spectacularscientifically accurate verses for the planets to Timothy Leary in prison. For the past four decades, she has been bridging science and the humanities in extraordinary explorations of everything from the science of the senses to thenatural history of love to the slender threads of hope. In The Human Age: The World Shaped By Us (public library | IndieBound), Ackerman traces how we got to where we are — a perpetually forward-leaning species living in a remarkable era full of technological wonders most of which didn’t exist a mere two centuries ago — when “only moments before, in geological time, we were speechless shadows on the savanna.”

With bewitchingly lyrical language, Ackerman paints the backdrop of our explosive evolution and its yin-yang of achievement and annihilation:

Humans have always been hopped-up, restless, busy bodies. During the past 11,700 years, a mere blink of time since the glaciers retreated at the end of the last ice age, we invented the pearls of Agriculture, Writing, and Science. We traveled in all directions, followed the long hands of rivers, crossed snow kingdoms, scaled dizzying clefts and gorges, trekked to remote islands and the poles, plunged to ocean depths haunted by fish lit like luminarias and jellies with golden eyes. Under a worship of stars, we trimmed fires and strung lanterns all across the darkness. We framed Oz-like cities, voyaged off our home planet, and golfed on the moon. We dreamt up a wizardry of industrial and medical marvels. We may not have shuffled the continents, but we’ve erased and redrawn their outlines with cities, agriculture, and climate change. We’ve blocked and rerouted rivers, depositing thick sediments of new land. We’ve leveled forests, scraped and paved the earth. We’ve subdued 75 percent of the land surface — preserving some pockets as “wilderness,” denaturing vast tracts for our businesses and homes, and homogenizing a third of the world’s ice-free land through farming. We’ve lopped off the tops of mountains to dig craters and quarries for mining. It’s as if aliens appeared with megamallets and laser chisels and started resculpting every continent to better suit them. We’ve turned the landscape into another form of architecture; we’ve made the planet our sandbox.

But Ackerman is a techno-utopian at heart. Noting that we’ve altered our relationship with the natural world “radically, irreversibly, but by no means all for the bad,” she adds:

Our relationship with nature is evolving, rapidly but incrementally, and at times so subtly that we don’t perceive the sonic booms, literally or metaphorically. As we’re redefining our perception of the world surrounding us, and the world inside of us, we’re revising our fundamental ideas about exactly what it means to be human, and also what we deem “natural.”

Dive deeper with Ackerman on what the future of artificial intelligence reveals about the human condition.

3. THE BOOK OF TREES

Why is it that when we behold the oldest living trees in the world, primeval awe runs down our spine? We are entwined with trees in an elemental embrace, both biological and symbolic, depending on them for the very air we breathe as well as for our deepest metaphors, millennia in the making. They permeate our mythology and our understanding of evolution. They enchant our greatest poets and rivet our greatest scientists. Even our language reflects that relationship — it’s an idea that has taken “root” in nearly every “branch” of knowledge.

How and why this came to be is what designer and information visualization scholar Manuel Lima explores in The Book of Trees: Visualizing Branches of Knowledge (public library | IndieBound) — a magnificent 800-year history of the tree diagram, from Descartes to data visualization, medieval manuscripts to modern information design, and the follow-up to Lima’s excellent Visual Complexity: Mapping Patterns of Information.

‘Genealogical distribution of the arts and sciences’ by Chrétien Frederic Guillaume Roth from Encyclopédie (1780)

A remarkable tree featured as a foldout frontispiece in a later 1780 edition of the French Encyclopédie by Denis Diderot and Jean le Rond d’Alembert, first published in 1751. The book was a bastion of the French Enlightenment and one of the largest encyclopedias produced at that time. This tree depicts the genealogical structure of knowledge, with its three prominent branches following the classification set forth by Francis Bacon in ‘The Advancement of Learning’ in 1605: memory and history (left), reason and philosophy (center), and imagination and poetry (right). The tree bears fruit in the form of roundels of varying sizes, representing the domains of science known to man and featured in the encyclopedia.

‘Tree of virtues’ by Lambert of Saint-Omer, ca. 1250

Palm tree illustration from the ‘Liber floridus (Book of flowers),’ one of the oldest, most beautiful, and best-known encyclopedias of the Middle Ages. Compiled between the years 1090 and 1120 by Lambert, a canon of the Church of Our Lady in Saint-Omer, the work gathers extracts from 192 different texts and manuscripts to portray a universal history or chronological record of the most significant events up to the year 1119. This mystical palm tree, also known as the ‘palm of the church,’ depicts a set of virtues (fronds) sprouting from a central bulb. The palm tree was a popular early Christian motif, rich in moral and symbolic associations, often used to represent the heavens or paradise.

‘Plan of Organization of New York and Erie Railroad’ by Daniel Craig McCallum (1855)

Diagram viewed by economists as one of the first organizational charts. The plan represents the division of administrative duties and the number and class of employees engaged in each department of the New York and Erie Railroad. Developed by the railroad’s manager, the engineer Daniel Craig McCallum, and his associates, the scheme features a total of 4,715 employees distributed among its five main branches (operating divisions) and remaining boughs (passenger and freight departments). At the roots of the imposing tree, in a circular layout, are the president and the board of directors.

Lima writes in the introduction:

In a time when more than half of the world’s population live in cities, surrounded on a daily basis by asphalt, cement, iron, and glass, it’s hard to conceive of a time when trees were of immense and tangible significance to our existence. But for thousands and thousands of years, trees have provided us with not only shelter, protection, and food, but also seemingly limitless resources for medicine, fire, energy, weaponry, tool building, and construction. It’s only normal that human beings, observing their intricate branching schemas and the seasonal withering and revival of their foliage, would see trees as powerful images of growth, decay, and resurrection. In fact, trees have had such an immense significance to humans that there’s hardly any culture that hasn’t invested them with lofty symbolism and, in many cases, with celestial and religious power. The veneration of trees, known as dendrolatry, is tied to ideas of fertility, immortality, and rebirth and often is expressed by the axis mundi (world axis), world tree, or arbor vitae (tree of life). These motifs, common in mythology and folklore from around the globe, have held cultural and religious significance for social groups throughout history — and indeed still do.

[…]

The omnipresence of these symbols reveals an inherently human connection and fascination with trees that traverse time and space and go well beyond religious devotion. This fascination has seized philosophers, scientists, and artists, who were drawn equally by the tree’s inscrutabilities and its raw, forthright, and resilient beauty. Trees have a remarkably evocative and expressive quality that makes them conducive to all types of depiction. They are easily drawn by children and beginning painters, but they also have been the main subjects of renowned artists throughout the ages.

Dive deeper here.

4. THE MEANING OF HUMAN EXISTENCE

Just as the fracturing of our inner wholenessruptures the soul, a similar fissure rips society asunder and has been for centuries — that between science and the humanities. The former explores how we became human and the latter what it means to be human — a difference at once subtle and monumental, polarizing enough to hinder the answering of both questions. That’s what legendary naturalist, sociobiologist, and Pulitzer-winning writer E.O. Wilson explores with great eloquence and intellectual elegance in The Meaning of Human Existence (public library |IndieBound).

Three decades after Carl Sagan asserted that “if we ever reach the point where we think we thoroughly understand who we are and where we came from, we will have failed,” Wilson — a longtime proponent of bridging the artificial divide between science and the humanities — counters that “we’ve learned enough about the Universe and ourselves to ask these questions in an answerable, testable form.”

And that elusive answer, he argues, has to do with precisely that notion ofmeaning:

In ordinary usage the word “meaning” implies intention, intention implies design, and design implies a designer. Any entity, any process, or definition of any word itself is put into play as a result of an intended consequence in the mind of the designer. This is the heart of the philosophical worldview of organized religions, and in particular their creation stories. Humanity, it assumes, exists for a purpose. Individuals have a purpose in being on Earth. Both humanity and individuals have meaning.

There is a second, broader way the word “meaning” is used and a very different worldview implied. It is that the accidents of history, not the intentions of a designer, are the source of meaning. There is no advance design, but instead overlapping networks of physical cause and effect. The unfolding of history is obedient only to the general laws of the Universe. Each event is random yet alters the probability of later events. During organic evolution, for example, the origin of one adaptation by natural selection makes the origin of certain other adaptations more likely. This concept of meaning, insofar as it illuminates humanity and the rest of life, is the worldview of science.

Whether in the cosmos or in the human condition, the second, more inclusive meaning exists in the evolution of present-day reality amid countless other possible realities.

The idea that we are a cosmic accident is far from new and, to the unexamined existential reflex, far from comforting. And yet, Wilson suggests, there is something enormously gladdening about the notion that out of all possible scenarios, out of the myriad other combinations that would have resulted in not-us, we emerged and made life meaningful. He illustrates this sense of “meaning” with the particular evolutionary miracle of the human brain, the expansion of which was among the most rapid bursts of complex tissue evolution in the known history of the universe:

A spider spinning its web intends, whether conscious of the outcome or not, to catch a fly. That is the meaning of the web. The human brain evolved under the same regimen as the spider’s web. Every decision made by a human being has meaning in the first, intentional sense. But the capacity to decide, and how and why the capacity came into being, and the consequences that followed, are the broader, science-based meaning of human existence.

Premier among the consequences is the capacity to imagine possible futures, and to plan and choose among them. How wisely we use this uniquely human ability depends on the accuracy of our self-understanding. The question of greatest relevant interest is how and why we are the way we are and, from that, the meaning of our many competing visions of the future.

Perched on the precipice of an era when the very question of what it means to be human is continually challenged, we stand to gain that much more from the fruitful cross-pollination of science and the humanities in planting the seeds for the best such possible futures. Like an Emerson of our technoscientific era, Wilson champions the ennobling self-reliance embedded in this proposition:

Humanity … arose entirely on its own through an accumulated series of events during evolution. We are not predestined to reach any goal, nor are we answerable to any power but our own. Only wisdom based on self-understanding, not piety, will save us.

Dive deeper here.

5. THE EDGE OF THE SKY

“If one cannot state a matter clearly enough so that even an intelligent twelve-year-old can understand it,” pioneering anthropologistMargaret Mead wrote in the 1979 volumeSome Personal Views, “one should remain within the cloistered walls of the university and laboratory until one gets a better grasp of one’s subject matter.” Whether or not theoretical cosmologist Roberto Trottaread Mead, he embodies her unambiguous ethos with heartening elegance in The Edge of the Sky: All You Need to Know About the All-There-Is (public library | IndieBound) — an unusual “short story about what we think the All-There-Is is made of, and how it got to be the way it is,” told in the one thousand most common words in the English language. Under such admirable self-imposed restriction — the idea for which was given to Trotta by Randall Munroe, who knows a thing or two about illuminating complexity through simplicity — Trotta composes a poetic primer on the universe by replacing some of the densest terminology of astrophysics with invariably lyrical synonyms constructed from these common English words. The universe becomes the “All-There-Is,” Earth our “Home World,” the planets “Crazy Stars,” our galaxy a “Star-Crowd” — because, really, whoever needs supersymmetric particles when one could simply say “Mirror Drops”?

What emerges is a narrative that explains some of the most complex science in modern astrophysics, told in language that sounds like a translation of ancient storytelling, like the folkloric fables of African mythology, the kinds of tales written before we had the words for phenomena, before we had the understanding that demanded those words. Language, after all, always evolves as a mashup of our most commonly held ideas.

Trotta’s story, which spans from the Big Bang (“Big Flash”) to the invention of the telescope (“Big-Seer”) to the discoveries and unknowns that play out at the Large Hadron Collider (“Big Ring”), also features a thoughtfully equalizing play of gender pronouns, casting both women and men as “student-people” — the protagonist-scientists in the history of cosmology and astrophysics.

The story is peppered with appropriately lyrical illustrations by French artistAntoine Déprez.

DARK MATTER: ‘In the time it takes you to blink, the number of dark matter drops that fly through your hand is two times the number of people living today in the city that never sleeps.’

In a particularly poetic chapter on space-time and the quest to grasp the scale of the universe, Trotta, who works at the astrophysics group of Imperial College London and has held research positions at Oxford and the University of Geneva, chronicles Einstein’s most enduring legacy:

Doctor Einstein was to become one of the most important student-people ever. He had a quick brain and he had been thinking carefully about the building blocks of the All-There-Is. To his surprise, he found that light was the key to understanding how far-away things in the sky — Crazy Stars, our Star-Crowd, and perhaps even the White Shadows — appear to us.

[…]

You could not explain this using the normal idea of space and time. Mr. Einstein then said that space and time had to be married and form a new thing that he called space-time. Thanks to space-time, he found that time slows down if you fly almost as fast as light and that your arm appears shorter in the direction you are going.

He then asked himself what would happen if you put some heavy stuff, as heavy as a star, in the middle of space-time. He was the first to understand that matter pulls in space-time and changes the way it looks. In turn, the form of space-time is what moves matter one way or another.

It followed that light from stars and the White Shadows in the sky would also be dragged around by the form of space-time. Understanding space-time meant understanding where exactly and how far away from us things are in the sky.

[…]

Mr. Einstein then began to wonder what would happen if he used his space-time idea for the entire All-There-Is.

LARGE HADRON COLLIDER: ‘Near that city, student-people have built a large ring under the ground. It would take you over five hours to walk around that Big Ring.’

But Trotta’s greatest feat is the grace with which he addresses the greatest question of cosmology, the one at the heart of the ancient tension betweenscience and religion — the idea that the universe we have seems like amiraculous accident since, despite an infinity of other possible combinations, it somehow cultivated the exact conditions that make life viable. Science rejects the idea of a grand “Creator” who orchestrated these conditions, and religious traditions are predicated on the terror of admitting to such purely accidental origin — a bind with which humanity still tussles vigorously to this day, yet one Trotta untangles with extraordinary intellectual elegance:

Imagine for a minute the following situation.

You enter a room where you find a table with a large number of small, gray, round pieces on it — of the type that you can use to buy a coffee, or a paper, or to pay for parking. The ones with one head on one side and some other picture on the flip side.

Let’s say that there are four hundred of the gray pieces on the table. And they all show heads.

You would not believe for a second that they were all just thrown on the table and happened to land this way. Although this could happen, it would be a hard thing to accept.

It would be easier to imagine that someone had walked into the room before you and had put them all down like this, heads up, all four hundred of them.

The strange thing about the Dark Push is that it is a bit like the four hundred heads-up gray pieces in the room.

If the Dark Push were only a tiny bit larger than it is, then everything we see around us would be very different.

It is as if changing only one of the heads in the four hundred would make the entire world change.

Change the Dark Push by a little bit, and Star-Crowds could not form; none of the stars we see in the sky would be there; the Sun would not be there; our Home-World would not be there; and life, as we know it, could not be here.

We wouldn’t be here to talk about this in the first place.

So the question is: Who or what put down all four hundred heads exactly this way?

MULTIVERSE THEORY: ‘Let’s say that there are four hundred of the gray pieces on the table. And they all show heads.’

Trotta offers an answer through a remarkably succinct explanation of the concept of the multiverse and the notion of parallel universes:

Some student-people came to believe that they could understand this by imagining more rooms. A very large number of rooms.

In each of them, the four hundred gray pieces are all thrown up in the air and flipped. And they land in some way, however they may.

In most of the rooms, some of pieces will land heads, and some won’t.

But if you have enough rooms, in the end you’ll find one room where all of the pieces have landed heads-up. Just like that.

There is no need to imagine anyone setting them up in this way.

It’s only a question of having enough rooms and trying them all.

And so the idea is that perhaps the All-There-Is is not all there is.

Dive deeper here.

6. THE SCIENCE OF SHAKESPEARE

William Shakespeare — to the extent that he existed at all — lived during a remarkable period in human history. Born the same year asGalileo, a founding father of the Scientific Revolution, and shortly before Montaigne, the Bard witnessed an unprecedented intersection of science and philosophy as humanity sought to make sense of its existence. One of the era’s most compelling sensemaking mechanisms was the burgeoning field of astronomy, which brought to the ancient quest to order the heavens a new spirit of scientific ambition.

In The Science of Shakespeare: A New Look at the Playwright’s Universe (public library |IndieBound), science journalist Dan Falk explores the curious connection between the legendary playwright and the spirit of the Scientific Revolution, arguing that the Bard was significantly influenced by science, especially by observational astronomy.

Of particular interest is what Falk calls “one of the most intriguing plays (and one of the most overlooked works) in the entire canon” — the romantic tragedyCymbeline. Pointing to a strange and highly symbolic scene in the play’s final act, where the hero sees in a dream the ghosts of his four dead family members circling around him as he sleeps, Falk writes:

Shakespeare’s plays cover a lot of ground, and employ many theatrical tricks — but as for gods descending from the heavens, this episode is unique; there is nothing else like it in the entire canon. Martin Butler calls the Jupiter scene the play’s “spectacular high point,” as it surely is. But the scene is also bizarre, unexpected, and extravagant — so much so that some have wondered if it represents Shakespeare’s own work.

[…]

If anything in Shakespeare’s late plays points to Galileo, this is it: Jupiter, so often invoked by characters in so many of the plays, never actually makes a personal appearance — until this point in Cymbeline. And of course Jupiter is not alone in the scene: Just below him, we see four ghosts moving in a circle. . . . Could the four ghosts represent the four moons of Jupiter, newly discovered by Galileo?

First atlas of the moon, 1647, from ‘Ordering the Heavens.’ Click image for more.

The timeline, Falk points out, is right — Cymbeline is believed to have been written in the summer or fall of 1610, mere months after the publication of Galileo’s short but seminal treatise on his initial telescopic observations,Sidereus Nuncius (Starry Messenger). Examining a specific passage from the play for evidence, Falk writes:

The passage seems to allude, at least in part, to the sights one might see in the heavens; at the very least, it has something to do with distinguishing different kinds of objects (including, it would seem, stars) from one another. But the context is crucial: The first line is spoken to Imogen; the remaining lines are clearly an aside, spoken only to the audience. He seems to be saying, My story is unbelievable; why would Posthumus stoop so low, when his own wife is so beautiful? After all, he reasons, the eye gives one the power to tell the stars apart, and even to distinguish one stone on the beach from another; can’t Posthumus see the difference between his wife and a common whore? [Penn State University astronomer Peter] Usher passes over the sexual aspect of these lines, however, and focuses on the astronomical: The “vaulted arch” is surely the sky; the “fiery orbs above” must be the stars. Could the precious “spectacles” be a reference to a telescope-like device?

Dive deeper here.

7. A STING IN THE TALE

The great E.O. Wilson is credited with having once said, “If all mankind were to disappear, the world would regenerate back to the rich state of equilibrium that existed ten thousand years ago. If insects were to vanish, the environment would collapse into chaos.” But while the one million or so named species of insects make up about 70% of all known species on Earth, one type of insect is more vital to our planet’s survival — as well as our own — than any other: the humble, mighty bee. In A Sting in the Tale: My Adventures with Bumblebees (public library |IndieBound), British biologist, lifelong wildlife enthusiast and Bumblebee Conservation Trustfounder Dave Goulson explores how bees gave our cosmic home not only its beauty but also its bounty of nourishment, and what responsibility we have — as Jane Goodall once eloquently urged — in repaying that existential gesture.

Inviting us into his evolutionary time machine, Goulson takes us back to the Cretaceous period, between 145.5 and 65.5 million years ago, when Earth was covered in lush forests of giant greenery. The dinosaurs had just taken to the air as newly evolved feathers produced the first birds. Our own ancestors at the time were small and unseemly rat-like creatures lurking under the ferns and feeding on insects and fallen fruit. Goulson writes:

If we could travel to this ancient land, we might be too concerned with the dangers posed by the larger wildlife to notice that there were no flowers; no orchids, buttercups or daisies, no cherry blossoms, no foxgloves in the wooded glades. And no matter how hard we listened, we would not hear the distinctive drone of bees. But all that was about to change.

So why did it change? It turns out that sex does indeed rule the world — two hundred million years after the first ejaculation in Earth’s recorded history, bees stepped in to perform a vital function in our planet’s blossoming into maturity:

Sex has always been difficult for plants, because they cannot move. If one cannot move, then finding a suitable partner and exchanging sex cells with them poses something of an obstacle. The plant equivalent of sperm is pollen, and the challenge facing a plant is how to get its pollen to the female reproductive parts of another plant; not easy if one is rooted to the ground. The early solution, and one still used by some plants to this day, is to use the wind. One hundred and thirty-five million years ago almost all plants scattered their pollen on the wind and hoped against hope that a tiny proportion of it would, by chance, land on a female flower. This is, as you might imagine, a very inefficient and wasteful system, with perhaps 99.99 per cent of the pollen going to waste – falling on the ground or blowing out to sea. As a result they had to produce an awful lot.

Nature abhors waste, and it was only a matter of time before the blind stumbling of evolution arrived at a better solution in the form of insects. Pollen is very nutritious. Some winged insects now began to feed upon it and before long some became specialists in eating pollen. Flying from plant to plant in search of their food, these insects accidentally carried pollen grains upon their bodies, trapped amongst hairs or in the joints between their segments. When the occasional pollen grain fell off the insect on to the female parts of a flower, that flower was pollinated, and so insects became the first pollinators, sex facilitators for plants. A mutualistic relationship had begun which was to change the appearance of the earth. Although much of the pollen was consumed by the insects, this was still a vast improvement for the plants compared to scattering their pollen to the wind.

But this system presented our proto-bees with a serious wayfinding problem: Because flowers were as drably brownish-green as the surrounding vegetation, spotting them was no small task. In order to attract insects, they had to get better at standing out over the competition and “advertising” their delicious pollen.

Dive deeper into how that happened here.

8. THE UNIVERSE

“The mystery of being is a permanent mystery,”John Updike once observed in pondering why the universe exists, and yet of equal permanence is the allure this mystery exerts upon the scientists, philosophers, and artists of any given era. The Universe: Leading Scientists Explore the Origin, Mysteries, and Future of the Cosmos (public library | IndieBound) collects twenty-one illuminating, mind-expanding meditations on various aspects of that mystery, from multiple dimensions to quantum monkeys to why the universe looks the way it does, by some of the greatest scientific thinkers of our time. It is the fourth installment in an ongoing series by Edgeeditor John Brockman, following Thinking (2013), Culture (2011), and The Mind(2011).

In one of the essays, theoretical physicist Leonard Suskind marvels at the unique precipice we’re fortunate to witness:

The beginning of the 21st century is a watershed in modern science, a time that will forever change our understanding of the universe. Something is happening which is far more than the discovery of new facts or new equations. This is one of those rare moments when our entire outlook, our framework for thinking, and the whole epistemology of physics and cosmology are suddenly undergoing real upheaval. The narrow 20th-century view of a unique universe, about 10 billion years old and 10 billion light years across with a unique set of physical laws, is giving way to something far bigger and pregnant with new possibilities.

Gradually physicists and cosmologists are coming to see our ten billion light years as an infinitesimal pocket of a stupendous megaverse.

Dive deeper with Harvard physicist Lisa Randall on “branes” and the science of multiple dimensions and some thoughts on gender in science publishing.

9. NEUROCOMIC

Scientists are only just beginning to understand how the brain works — from what transpires in it while we sleep to how to optimize its memoryto what love does to it to how music affects it — and the rest of us fall somewhere on the spectrum between fascinated and confused when it comes to the intricate inner workings of our master-controller.

From British indie press Nobrow — who also brought us Freud’s graphic biography and Blexbolex’s magnificent No Man’s Land — comes Neurocomic (public library | IndieBound), a graphic novel about how the brain works. This remarkable collaboration between neuroscientist Dr. Hana Roš and neuroscience-PhD-turned-illustrator Dr. Matteo Farinella, with support from the Wellcome Trust, explains the inner workings of the brain in delightful and illuminating black-and-white illustrations, covering everything from perception and hallucinations to memory and emotional recall to consciousness and the difference between the mind and the brain.

We take a stroll through a forest of neurons, then learn about neuroplasticity. (“This is the great power of the brain, it’s plastic!” they tell us in one of the most heartening and reassuring parts. “Once you learn something it is not set in stone, it’s continuously shaped by experience.”) We meet Pavlov and his famous studies of memory in 1897 Russia. We visit the haunting memory caves and the convoluted castles of deception.

This wonderful trailer for the film about the project, directed by Richard Wyllie, takes us behind the scenes of the duo’s marvelous collaboration and creative process:

See more here.

10. THE TALE OF THE DUELING NEUROSURGEONS

“In both writing and sleeping,” Stephen King wrote in his meditation on “creative sleep” and the art of wakeful dreaming, “we learn to be physically still at the same time we are encouraging our minds to unlock from the humdrum rational thinking of our daytime lives.”But while he was exploring the creative process from a metaphorical angle, he was inadvertently describing one of the greatest neurological nightmares that could befall us. Due to the sheer enormity of what happens in the brain while we sleep, there is also a sizable possibility that things would go wrong; when they do, things can get scary. And few sleep-related brain glitches can be scarier than what is known as “sleep paralysis” — the evil twin of lucid dreaming.

Four years after The Disappearing Spoon, his wonderful chronicle of crazy tales from the periodic table, science writer Sam Kean returns with The Tale of the Dueling Neurosurgeons: The History of the Human Brain as Revealed by True Stories of Trauma, Madness, and Recovery (public library | IndieBound) — a mind-bending tour of the mind, which Kean opens with a fascinating example, at once very personal and powerfully illustrative of the brain’s humbling complexity:

I can’t fall asleep on my back — or rather, I don’t dare to. In that position I often slip into a fugue state where my mind wakes up from a dream, but my body remains immobile. In this limbo I can still sense things around me: sunlight trickling through the curtains, passersby on the street below, the blanket tented on my upturned feet. But when I tell my body to yawn and stretch and get on with the day, nothing happens. I’ll recite the command again — Move, you — and the message echoes back, unheeded. I fight, I struggle, I strain to twiddle a toe or flex a nostril, and it does no good. It’s what being reincarnated as a statue would feel like. It’s the opposite of sleepwalking — it’s sleep paralysis.

The worst part is the panic. Being awake, my mind expects my lungs to take full, hearty breaths — to feel my throat expanding and my sternum rising a good six inches. But my body — still asleep, physiologically — takes mere sips of air. I feel I’m suffocating, bit by bit, and panic begins to smolder in my chest.

Dive deeper with Kean’s explanation of how this Rube Goldberg machine of neurological disaster sheds light on how the healthy brain works.

11. WHAT IF?

For years, NASA-roboticist-turned-comic-creator Randall Munroe has been delighting the world with his popular xkcd webcomic, often answering readers’ questions about various aspects of how the world works with equal parts visual wit and scientific rigor. The best of these, as well as a number of never-before-answered ones, are now collected inWhat If?: Serious Scientific Answers to Absurd Hypothetical Questions (public library| IndieBound) — questions like what would happen if a submarine was hit by lightning to what it would actually take to eradicate the common cold to the physics of trying to hit a baseball pitched at the speed of light.

Munroe writes in the introduction:

I’ve been using math to try to answer weird questions for as long as I can remember. When I was five years old, my mother had a conversation with me that she wrote down and saved in a photo album. When she heard I was writing this book, she found the transcript and sent it to me. Here it is, reproduced verbatim from her 25-year-old sheet of paper:

Randall: Are there more soft things or hard things in our house?

Julie: I don’t know.Randall: How about in the world?

Julie: I don’t know.

Randall: Well, each house has three or four pillows, right?

Julie: Right.

Randall: And each house has about 15 magnets, right?

Julie: I guess.

Randall: So 15 plus 3 or 4, let’s say 4, is 19, right?

Julie: Right.

Randall: So there are probably about 3 billion soft things, and . . . 5 billion hard things. Well, which one wins?

Julie: I guess hard things.

To this day I have no idea where I got “3 billion” and “5 billion” from. Clearly, I didn’t really get how numbers worked.

My math has gotten a little better over the years, but my reason for doing math is the same as it was when I was five: I want to answer questions.

They say there are no stupid questions. That’s obviously wrong; I think my question about hard and soft things, for example, is pretty stupid. But it turns out that trying to thoroughly answer a stupid question can take you to some pretty interesting places.

Dive deeper with Munroe exploration of the math of finding your soul mate.

12. NOTHING

In 2013, Neil deGrasse Tyson hosted a mind-bending debate on the nature of “nothing” — an inquiry that has occupied thinkers since the dawn of recorded thought and permeates everything from Hamlet’s iconic question to the boldest frontiers of quantum physics. That’s precisely what New Scientist editor-in-chief Jeremy Webb explores with a kaleidoscopic lens in Nothing: Surprising Insights Everywhere from Zero to Oblivion(public library | IndieBound) — a terrific collection of essays and articles exploring everything from vacuum to the birth and death of the universe to how the concept of zero gained wide acceptance in the 17th century after being shunned as a dangerous innovation for 400 years. Webb writes:

You might think a book about nothing sounds suspiciously like an oxymoron. But fortunately there’s plenty to explore, because nothing has been a topic of discussion for more than 2,000 years: indeed, the ancient Greeks had a lively disagreement about it. And such have been the changing fortunes of nothing that you can pretty much tell where you are in history just by finding out the prevailing views on nothing.

Take zero, for example, the symbol for the absence of things. Part of it came into being in Babylonia around 300 bc. The rest of it emerged 1,000 years later when the Indians fused that idea with an ancient symbol for nothingness. Another 400 years passed before it arrived in Europe where it was initially shunned as a dangerous innovation. By the 17th century it had gained acceptance, and today it is critical to the definition of every number you use.

[…]

Nothing becomes a lens through which we can explore the universe around us and even what it is to be human. It reveals past attitudes and present thinking.

[…]

Nothings can be difficult to attain: we haven’t reached absolute zero and most likely never will . Nothings can also be messy: what is described as the vacuum of space turns out to be not one, but many. And nothings can be powerful: sick people can get better after talking with a doctor even though nothing material passes between them.

Dive deeper with Jo Marchant’s mind-bending account of the latter power of nothingness — a look at the new science of the placebo effect and how our minds actually affect our bodies.

13. 30 DAYS

“The ideal scientist thinks like a poet and works like a bookkeeper,” the influential biologist E.O. Wilson said in his spectacular recent conversation with the former Poet Laureate Robert Hass, exploring the shared creative wellspring of poetry and science. A beautiful embodiment of it comes from 30 Days, an unusual and bewitching series of “quantum poetry” by xYz — the pseudonym of British biologist and poet Joanna Tilsley, who began writing poetry at the age of eight and continued, for her own pleasure, until she graduated college with a degree in biology. In April of 2013, while undergoing an emotional breakdown, Tilsley took a friend up on a dare and decided to participate in NaPoWriMo — an annual creative writing project inviting participants to write a poem a day for a month. Immersed in cosmology and quantum physics at the time, she found herself enchanted by the scientific poetics of nature as she strolled around her home in North London. Translating that enchantment in lyrical form, she produced a series of thirty poems on everything from DNA to the exoplanet Keppler-62F, a “super-Earth-sized planet orbiting a star smaller and cooler than the sun,” to holometabolism, the process by which the caterpillar metamorphoses into a butterfly, to the Soviet cosmonaut Yuri Gagarin, the first human being to see Earth from space.

Tilsley’s choice of pseudonym is itself remarkably poetic — besides the scientific sensibility, XYZ was the pen name of her grandfather, the late British novelist and war correspondent Frank Tilsley.

Tilsley wrote and illustrated her quantum poems simultaneously, using her vast collection of scanned vintage paper ephemera, old typewriter fonts, and 19th-century artwork (I recognize Benjamin Betts’s “geometrical psychology” illustrations), which she manipulated digitally into beautiful backdrops for her verses. Not unlike the work of William Blake, text and image work together to channel a cohesive atmosphere.

It’s also interesting that Tilsley chose to capitalize nouns and pronouns in the style of religious texts — a poignant juxtaposition with the scientific sensibility of the poems, hinting, consciously or not, at the spiritual element of science.

14. DATACLYSM

In Dataclysm: Who We Are (When We Think No One’s Looking) (public library | IndieBound), writer, musician, and entrepreneur Christian Rudder takes a remarkable look at how person-to-person interaction from just about every major online data source of our time reveal human truths “deeper and more varied than anything held by any other private individual,” and how the tension “between the continuity of the human condition and the fracture of the database” actually sheds light on some of humanity’s most immutable mysteries.

Rudder is the co-founder of the dating siteOKCupid and the data scientist behind its now-legendary trend analyses, but he is also — as it becomes immediately clear from his elegant writing and wildly cross-disciplinary references — a lover of literature, philosophy, anthropology, and all the other humanities that make us human and that, importantly in this case, enhance and ennoble the hard data with dimensional insight into the richness of the human experience. Rudder writes:

I don’t come here with more hype or reportage on the data phenomenon. I come with the thing itself: the data, phenomenon stripped away. I come with a large store of the actual information that’s being collected, which luck, work, wheedling, and more luck have put me in the unique position to possess and analyze.

For the reflexively skeptical, Rudder offers assurance by way of his own self-professed “luddite sympathies”:

I’ve never been on an online date in my life and neither have any of the other founders, and if it’s not for you, believe me, I get that. Tech evangelism is one of my least favorite things, and I’m not here to trade my blinking digital beads for anyone’s precious island. I still subscribe to magazines. I get the Times on the weekend. Tweeting embarrasses me. I can’t convince you to use, respect, or “believe in” the Internet or social media any more than you already do—or don’t. By all means, keep right on thinking what you’ve been thinking about the online universe. But if there’s one thing I sincerely hope this book might get you to reconsider, it’s what you think about yourself. Because that’s what this book is really about. OkCupid is just how I arrived at the story.

Dive deeper with the data on what it really means to be extraordinary.

15. EVOLUTION

We were once amoebae, and here we are today, singing opera and typing on iPhones with opposable thumbs. That alone is enough marvel to put the petty nuisances of everyday life in perspective and fill our human hearts with humility.

As a lover of unusual coloring books and ofscience-oriented children’s books, especially ones that replace myth with science, I was instantly smitten with Evolution: A Coloring Book (public library | IndieBound) by London-based Finnish illustrator Annu Kilpeläinen — the best thing since Darwin’s graphic biography, and also a fine addition to the best children’s books of the year.

This simple yet imaginative primer on science via art explores natural selection, continental drift, what killed the dinosaurs, how birds descended from them, and all the other processes and phenomena that took us to where we are today. Die-cut delights add an element of interactive playfulness to the classic coloring-book experience.

One particularly apt application of the die-cut technique is a series of pages which, through strategically placed cuts, invite an exploration of how human facial features evolved.

Supplement with Bill Nye’s grownup version, Undeniable: Evolution and the Science of Creation.

Recharge your phone in 30 seconds? Israeli firm says yes


An Israeli company says it has developed technology that can charge a mobile phone in a few seconds and an electric car in minutes — advances that could transform two of the world’s most dynamic consumer industries.

Using nanotechnology to synthesise artificial molecules, Tel Aviv-based StoreDot says it has developed a battery that can store a much higher charge more quickly, in effect acting like a super-dense sponge to soak up power and retain it.

While the prototype is currently far too bulky for a mobile phone, the company believes it will be ready by 2016 to market a slim battery that can absorb and deliver a day’s power for a smart phone in just 30 seconds.

“These are new materials, they have never been developed before,” said Doron Myersdorf, the founder and chief executive of StoreDot, whose investors include Russian billionaire and Chelsea soccer club owner Roman Abramovich.

The innovation is based around the creation of “nanodots,” which StoreDot describes as bio-organic peptide molecules. Nanodots alter the way a battery behaves to allow the rapid absorption and, critically, the retention of power.

The company has raised $48 million from two rounds of funding, including backing from a leading mobile phone maker. Myersdorf declined to name the company, but said it was Asian.

With the number of smart phone users forecast to reach 1.75 billion this year, StoreDot sees a big market, and some experts think that with more work, it could be on to a winner.

“We live in a power hungry world … People are constantly chasing a power outlet. StoreDot has the potential to solve this real big problem,” said Zack Weisfeld, who has worked with and evaluated ventures in the mobile phone sector globally.

“They still have some way to go, to deal with size of battery and power cycle rounds, but if solvable, it’s a very big breakthrough,” he said. A power cycle round refers to the number of times a battery can be re-charged in its lifetime.

Myersdorf said a fast-charge phone would cost $100-$150 more than current models and would ultimately be able to handle 1,500 recharge/discharge cycles, giving it about three years of life.

He hopes to use the same technology to create a car battery that recharges in two or three minutes, rather than current models which commonly need to be charged overnight.

 

Brain’s dementia weak spot found


Conceptual computer artwork depicting neurology. From left to right: MRI brain scans, 3D dsi white matter brain scan, brain, Alzheimer's brain versus normal brain, MRI brain scan

The brain has a weak spot for Alzheimer’s disease and schizophrenia, according to UK scientists who have pinpointed the region using scans.

The brain area involved develops late in adolescence and degenerates early during ageing.

At the moment, it is difficult for doctors to predict which people might develop either condition.

The findings, in the journal PNAS, hint at a potential way to diagnose those at risk earlier, experts say.

Although they caution that “much more research is needed into how to bring these exciting discoveries into the clinic”.

“Start Quote

Early doctors called schizophrenia ‘premature dementia’ but until now we had no clear evidence that the same parts of the brain might be associated with two such different diseases”

Prof Hugh Perry of the MRC

Weak spot

The Medical Research Council team who carried out the study did MRI brain scans on 484 healthy volunteers aged between eight and 85 years.

The researchers, led by Dr Gwenaëlle Douaud of Oxford University, looked at how the brain naturally changes as people age.

The images revealed a common pattern – the parts of the brain that were the last to develop were also the first to show signs of age-related decline.

These brain regions – a network of nerve cells or grey matter – co-ordinate “high order” information coming from the different senses, such as sight and sound.

When the researchers looked at scans of patients with Alzheimer’s disease and scans of patients with schizophrenia they found the same brain regions were affected.

The findings fit with what other experts have suspected – that although distinct, Alzheimer’s and schizophrenia are linked.

Prof Hugh Perry of the MRC said: “Early doctors called schizophrenia ‘premature dementia’ but until now we had no clear evidence that the same parts of the brain might be associated with two such different diseases. This large-scale and detailed study provides an important, and previously missing, link between development, ageing and disease processes in the brain.

“It raises important issues about possible genetic and environmental factors that may occur in early life and then have lifelong consequences. The more we can find out about these very difficult disorders, the closer we will come to helping sufferers and their families.”

Dr Michael Bloomfield of University College London said: “Schizophrenia can be potentially devastating but at the moment it’s very difficult to predict with certainty who is going to have a good prognosis and who might have a poor one.

“This study brings us a step closer to being able to make this prediction, so patients could in the future receive better targeted treatments.”

Armed with this new knowledge, it may also be possible to understand how to prevent the brain changes before they occur, he said

Polar sub gauges sea ice thickness


AUV seen under the Sea Ice
If the ice closes up, there is a risk the AUV may never be recovered

A novel autonomous sub has acquired the first detailed, high-resolution 3D maps of Antarctic sea ice.

Released from a ship, the vehicle criss-crossed the underside of the floes, using upward-looking sonar to measure their shape.

The researchers involved in the project tell the journal Nature Geoscience that the thickness of the pack ice was greater than they had been anticipated.

But they also caution against making generalisations from limited sampling.

Antarctic sea ice at its peak extent can cover 20 million square km; the research team on the other hand looked at just six small boxes some 500m along the square.

Nonetheless, the UK/US/Australia group got its proof-of-principle Autonomous Underwater Vehicle (AUV) into previously hard-to-reach places.

The hope is that this early demonstration will lead in the future to more effective means of assessing the volume of marine ice circling the White Continent.

This topic has become one of the most interesting questions in climate science in recent years as its trend line grows in the face of a warming planet.

Deep-winter sea ice in Antarctica now stands at an all-time high, as measured in the modern satellite record – and researchers are trying to work out why it has not followed the sharp decline seen in the Arctic.

“Antarctic sea has been kind of the poor sister,” says Jeremy Wilkinson from the British Antarctic Survey.

“A lot of effort has gone into measuring Arctic sea ice, and we’re only now just scratching the surface of Antarctic sea ice, especially in respect to thickness,” he told BBC News.

“We want to understand how it is changing and how that integrates with climate and ecosystem changes.

“It’s only by bringing all the processes together that we will be able to model them and say what’s going on in the Antarctic.”

The AUV, known as SeaBED, was developed at the Woods Hole Oceanographic Institution (WHOI) in the US.

It is about 2m in length, weighs nearly 200kg, and sports a twin-hull design that gives it enhanced stability.

SeaBed was released in the Antarctic spring seasons of 2010 and 2012 to sample ice thickness in six locations that included the Bellingshausen and Weddell seas, to the west of the continent, and off Wilkes Land, to the east.

The sub autonomously went about its business, tracking a “lawnmower pattern” under the ice for several hours before returning to the launch ship for recovery.

Sea ice map
A sample from one survey where the shape of the ice draft (that part of the floe below water) runs from zero metres thick (deep blue) to 8m thick (deep red)

That in itself is quite an achievement.

“Here’s the hard part: the ice floes that we want to map are all moving,” explains WHOI’s Hanumant Singh.

“What you do is place transponders in the ice so that the sub can move relative to those and produce a map that is consistent.

“The other big problem is that the ice will close up. In the six to eight hours that it takes to do one of these missions, the ice conditions change dramatically, and the hole you dropped the AUV in may have gone by the time the survey’s finished.

“You then just have to hope that a new hole has opened up next to your ship, which has itself by then also moved.”

The researchers found that, on average, the thickness of the ice beneath sea level was 1.4 to 5.5m, with the thickest sea ice measured at 16m.

They also encountered a lot of highly deformed ice, where one block had ridden over another, increasing the overall draft.

Drilling the sea ice in the Bellingshausen sea to deploy  a navigational transceiver
The research team puts out navigational transceivers to keep track of a moving icescape
Recovery at sunset

Antarctic sea ice measurements in the past have largely been limited to shipboard observations and drill holes – both of which are likely to bias to thinner ice (for example, a ship’s captain prefers to drive a vessel through the thinnest packs to avoid getting stuck).

A more global assessment would use satellites but these have difficulty working in the Antarctic because of the deep snow drifts that can accumulate on top of the floes.

These will hide the true shape of the ice and if the weight of the snow is substantial may even press the floes into the water column.

But Dr Wilkinson is hopeful that this and future sub studies will enable researchers to tease apart such details, to allow satellites to better gauge what they see below them.

“What we can do is take what these subs are showing us and then develop the algorithms that can be used by satellites to get a better synoptic scale,” he told BBC News.

“Another approach is to use longer-range AUVs that can give you a couple of hundred km [along the square] and go after the key areas that are changing, and to monitor those over time,” said Dr Wilkinson.

WHOI continues to develop its sub technology. It plans next to deploy a torpedo-like vehicle that can move faster and cover much wider sampling areas.

“The vehicle that we have now is relatively inexpensive at half a million dollars, but we’d like to get that down to maybe $100,000-150,000, so that when we lose a vehicle – and you will at some point lose one – we won’t cry too much,” said Dr Singh.

Emperor penguin on the sea ice
Antarctic sea ice as a whole has grown in extent in recent years
WHOI's Hanumant Singh
Hanumant Singh and his WHOI colleagues developed the underwater robot

Thai tasting robot tests authenticity


 

Video still of Jay Fai
Chef Jay Fai’s tom yum gung is renowned in Bangkok, but can it pass a robot taste test?

At a small laboratory in a Bangkok suburb, a group of scientists has come up with what they hope is the answer to an old conundrum: how to tell if a Thai dish is authentic or not.

It carries the simple name e-Delicious, and it takes the form of a box about the size of a large printer, containing sensors, and some computer circuitry, which act as an electronic tongue and nose.

It was developed by Thailand’s National Innovation Agency, at a total cost of $1m (£640,000), after former Prime Minister Yingluck Shinwatra complained about the poor versions of Thai food she was subjected to during her overseas trips.

A Thai Delicious committee was formed – a bit like the French Appellation d’Origine Contrôlée for food and wine – and around 200 people were invited to sample different versions of classic Thai dishes like tom yum gung (sour prawn soup) and kaeng khiao wan (green curry).

Whichever version was the consensus winner was taken as the standard, although the designers acknowledge that as the sampling was done in Bangkok, inevitably their standards for now are Bangkok versions.

The e-Delicious machine has nine sensors in it to measure the balance of six Thai flavours – sweet, sour, bitter, salty, savoury and spicy – and the food’s aroma.

There is also a sensor to assess the dish’s visual presentation, which is always very important in Thai cooking.

But can it actually tell you if the dish is any good?

Video still of scientists testing a bowl of tom yum gung
The Thai government sank $1m into developing the e-Delicious machine

“The machine can’t tell you if something is delicious or not,” says Nakah Thawichawatt, an entrepreneur who carries the grand title of Innovation Ambassador.

“The sensors give a taste-reading that we can understand. So if we like a certain taste, but can’t explain what that taste is to someone else, the machine will able to decipher it, and record the data as a standard for other dishes.”

‘Mozart of the Wok’

We decided to give the e-Delicious a test. We had seen it sample low-cost versions of the recipes in its database – only three for now, but soon to reach 10 – and found them all wanting.

But how would it cope with the tom yum gung that is judged by many in Bangkok to be the finest in the city?

You won’t find it in a ritzy restaurant in Bangkok’s upmarket neighbourhoods, where Italian or Japanese cuisine is popular.

Jay Fai, a formidable-looking woman in trademark beanie-hat and fire-engine slash of lipstick, is sometimes called the Mozart of the Wok, for the lightning speed and instinctive flair with which she wields that most essential tool for East Asian cooking.

Her pad kee mao, or drunken noodles, is renowned: thick strips of white rice noodles fried in seconds over a roaring charcoal brazier, the meat, seafood, vegetables and chillies seared, glazed and smoky.

But it is her tom yum gung they queue up for, despite a price tag that reaches $50 for a large bowl.

Jay Fai tells me she learned her recipes from the old women who used to cook for the community on the village where she grew up.

She is meticulous about ingredients, searching for the very freshest jumbo prawns, the most fragrant herbs – and tom yum gung relies a great deal on the galangal, lemon grass and lime leaves that flavour it, along with the fermented fish sauce, tamarind, lime juice, chillies and red onions.

Watching her hurling great handfuls of herbs into the furiously boiling pot, it is hard to see any precision.

And yet, after a couple of minutes she produces a soup of exquisite, overpowering taste and aroma. Once eaten, never forgotten, and for this reviewer, never equalled.

At the Thai Delicious lab we spooned some of Jay Fai’s soup into two glass beakers – one for taste, one for smell – and slid them into the e-Delicious machine.

After a minute’s processing, it delivered its verdict; for taste, 90%. For aroma, 100% – the highest score of any tom yum gung it had assessed.

So perhaps a machine can judge great cooking.

‘Taste is subjective’

For a final view I called the chef at the first Thai restaurant ever to win a Michelin star: David Thompson, a true global culinary celebrity.

His Bangkok restaurant Nahm has repeatedly been voted as one of the world’s finest.

“It’s an impossible dream, to set one standard,” he said. “Taste is so subjective.”

“There are standards, but the art of cooking is the epitome of humanity, with differences in taste, seasoning and technique that express the cook’s character.”

Prime Minister of Thailand, Ms Yingluck Shinawatra and Australian chef David Thompson cook traditional Thai food during a Thai food promotion and cooking demonstration at the Shangri-La Hotel on 27 May 2012 in Sydney, Australia
Mr Thompson, seen here in 2012 with Ms Shinawatra, is known as one of the top Thai chefs in the world

And what about a taste robot?

“It’s a gimmick, a foolish idea,” he said. “Any cook, any sound practitioner or craftsman knows that a robot can never analyse the product of the human hand.”

The developers of the e-Delicious machine are undeterred.

Despite its high cost – at least $18,000 per unit – they hope they can sell a few to each country where Thai food has taken off, to offer at least a consistent standard by which Thai restaurants can come and have their versions of the Thai classics judged.

And if that does not take off, they have also come up with a Thai Delicious app for smartphones

Wireless electronic implants stop staph, then dissolve


Researchers at Tufts University, in collaboration with a team at the University of Illinois at Champaign-Urbana, have demonstrated a resorbable electronic implant that eliminated bacterial infection in mice by delivering heat to infected tissue when triggered by a remote wireless signal. The silk and magnesium devices then harmlessly dissolved in the test animals. The technique had previously been demonstrated only in vitro. The research is published online in the Proceedings of the National Academy of Sciences Early Edition the week of November 24-28, 2014.

“This is an important demonstration step forward for the development of on-demand medical devices that can be turned on remotely to perform a therapeutic function in a patient and then safely disappear after their use, requiring no retrieval,” said senior author Fiorenzo Omenetto, professor of biomedical engineering and Frank C. Doble professor at Tufts School of Engineering. “These wireless strategies could help manage post-surgical infection, for example, or pave the way for eventual ‘wi-fi’ drug delivery.”

Implantable typically use non-degradable materials that have limited operational lifetimes and must eventually be removed or replaced. The new wireless therapy devices are robust enough to survive mechanical handling during surgery but designed to harmlessly dissolve within minutes or weeks depending on how the silk protein was processed, noted the paper’s first author, Hu Tao, Ph.D., a former Tufts post-doctoral associate who is now on the faculty of the Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences.

Each fully dissolvable wireless heating device consisted of a serpentine resistor and a power-receiving coil made of magnesium deposited onto a layer. The magnesium heater was encapsulated in a silk “pocket” that protected the electronics and controlled its dissolution time.

Devices were implanted in vivo in S. aureus infected tissue and activated by a wireless transmitter for two sets of 10-minute heat treatments. Tissue collected from the mice 24 hours after treatment showed no sign of infection, and surrounding tissues were found to be normal. Devices completely dissolved after 15 days, and magnesium levels at the implant site and surrounding areas were comparable to levels typically found in the body.

The researchers also conducted in vitro experiments in which similar remotely controlled devices released the antibiotic ampicillin to kill E. coli and S. aureus bacteria. The wireless activation of the devices was found to enhance antibiotic release without reducing antibiotic activity.